Ultrasonic evidence for structural relaxation in large unilamellar liposomes
The Journal of the Acoustical Society of America, 1983The ultrasonic absorption of large unilamellar vesicles (average diameter 0.2 μm) was determined in the frequency range 0.5–5 MHz. The liposomes were composed of a 4:1 mixture by weight of dipalmitoyl phosphatidylcholine and dipalmitoyl phosphatidylglycerol.
P R, Strom-Jensen, R L, Magin, F, Dunn
openaire +2 more sources
Polyelectrolyte-Coated Unilamellar Nanometer-Sized Magnetic Liposomes
Langmuir, 2009Superparamagnetic nanoparticles were encapsulated in liposomes prior to the stepwise adsorption of polyelectrolytes of opposite charges commonly known as the layer-by-layer (LbL) technique. Magnetic fields allow a fast separation of coated liposomes from unbound polyelectrolytes. The coated particles were characterized by dynamic light scattering (DLS),
Pereira da Silva Gomes, Joana Filipa +5 more
openaire +3 more sources
Cholesterol stimulation of penetration of unilamellar liposomes by hydrophobic compounds
The Journal of Membrane Biology, 1977The incorporation of cholesterol into unilamellar liposomes greatly increased the transmembranous movement of hydrophobic ionophores such as nigericin. In reconstituted liposomes containing rhodopsin as the only protein, the presence of cholesterol lowers by 10-fold or more the amount of negericin required to eliminate the light-driven proton gradient.
E F, LaBelle, E, Racker
openaire +2 more sources
Solubilization of Large Unilamellar Liposomes by Alkyl Glycosides
Journal of Colloid and Interface Science, 1997The study of biological membranes involves the dissociation, characterization and re-assembly of membrane components. The most important aspect of this approach is the use of an appropriate surfactant as solubilizing agent. In this work the solubilization of large unilamellar liposomes by alkyl glycosides has been studied.
, Ribosa +3 more
openaire +2 more sources
Encapsulation of doxorubicin in thermosensitive small unilamellar vesicle liposomes
European Journal of Cancer and Clinical Oncology, 1991The optimisation of the formulation of thermosensitive, doxorubicin-containing small unilamellar liposomes is described. The liposomes were first strictly defined in terms of size distribution and size stability and a quality level was defined. The suspension contained more than 95% vesicles with a maximal diameter of 50 nm and kept this level for a ...
openaire +2 more sources
Reactivity of Mammalian 15-Lipoxygenase with Phospholipids in Large Unilamellar Liposomes
Biochemical and Biophysical Research Communications, 1996The reactivity of rabbit reticulocyte 15-lipoxygenase (15-LOX) with phosphatidylcholine (PC) possessing linoleic acid (LA-PC), arachidonic acid (AA-PC), or docosahexaenoic acid (DHA-PC) was investigated by measuring oxygen uptake in the suspension of large unilamellar liposomes (LUV). The 15-LOX reaction with PC LUV was found to follow Michaelis-Menten
H, Arai, T, Suzuki, K, Takama, J, Terao
openaire +2 more sources
Temperature-Dependent Drug Release from Large Unilamellar Liposomes
Cancer Drug Delivery, 1984The drug-release properties of large unilamellar liposomes were measured at temperatures near the lipid's phase-transition temperature. The liposomes were formed from a mixture of dipalmitoylphosphatidylcholine and dipalmitoylphosphatidylglycerol (4:1 by weight) by the reverse-phase evaporation process.
R L, Magin, M R, Niesman
openaire +2 more sources
Thermodynamic modeling and cryomicroscopy of cell-size, unilamellar, and paucilamellar liposomes
Cryobiology, 1985Cryomicroscope studies of large unilamellar liposomes indicate that liposomes are an excellent model for studying membrane response to freezing and thawing. Liposomes are attractive for such use because they can be custom-manufactured for a particular investigation.
R A, Callow, J J, McGrath
openaire +2 more sources
Factors Affecting Responsivity of Unilamellar Liposomes to 20 kHz Ultrasound
Langmuir, 2004Ultrasound is commonly used in the preparation of unilamellar liposome dispersions and is often considered for cell membrane disruption for drug delivery or DNA transfection applications. To better understand the physical and chemical properties of lipid membranes that render them susceptible to ultrasonic permeabilization, the roles of temperature ...
Hung-Yin, Lin, James L, Thomas
openaire +2 more sources
Incorporation of bacteriorhodopsin into large unilamellar liposomes by reverse phase evaporation
Biochemical and Biophysical Research Communications, 1983The reverse phase evaporation procedure was used to prepare large unilamellar liposomes containing bacteriorhodopsin. Electron microscopy showed that proteoliposomes were unilamellar and fairly uniform in size provided the preparation was extruded through calibrated nucleopore membranes : the vesicles have diameters around 200 nm.
J L, Rigaud, A, Bluzat, S, Buschlen
openaire +2 more sources

