Results 191 to 200 of about 23,528 (221)
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Factors Affecting Responsivity of Unilamellar Liposomes to 20 kHz Ultrasound
Langmuir, 2004Ultrasound is commonly used in the preparation of unilamellar liposome dispersions and is often considered for cell membrane disruption for drug delivery or DNA transfection applications. To better understand the physical and chemical properties of lipid membranes that render them susceptible to ultrasonic permeabilization, the roles of temperature ...
Hung-Yin, Lin, James L, Thomas
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Encapsulation of doxorubicin in thermosensitive small unilamellar vesicle liposomes
European Journal of Cancer and Clinical Oncology, 1991The optimisation of the formulation of thermosensitive, doxorubicin-containing small unilamellar liposomes is described. The liposomes were first strictly defined in terms of size distribution and size stability and a quality level was defined. The suspension contained more than 95% vesicles with a maximal diameter of 50 nm and kept this level for a ...
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Covalent Immobilization of Unilamellar Liposomes in Gel Beads for Chromatography
Analytical Biochemistry, 1999For immobilized (proteo)liposome chromatography, unilamellar liposomes were covalently bound within gel beads that had been activated by CNBr, N-hydroxysuccinimide, tresyl, or chloroformate. Liposomes composed of phosphatidylcholine (PC) and 2 mol% of amino-containing lipid (phosphatidylethanolamine-caproylamine) were immobilized in the activated gels ...
Q, Yang +4 more
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Cholesterol stimulation of penetration of unilamellar liposomes by hydrophobic compounds
The Journal of Membrane Biology, 1977The incorporation of cholesterol into unilamellar liposomes greatly increased the transmembranous movement of hydrophobic ionophores such as nigericin. In reconstituted liposomes containing rhodopsin as the only protein, the presence of cholesterol lowers by 10-fold or more the amount of negericin required to eliminate the light-driven proton gradient.
E F, LaBelle, E, Racker
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TLC Characterization of Small Unilamellar Liposomes Containing D-myo-Inositol Derivatives
Biomedical Chromatography, 1996The thin-layer chromatographic (TLC) behaviour of small unilamellar liposomes containing inositol phosphates (IPs) was studied. The vesicles contained different concentrations of D-myo-inositol 1,4,5-triphosphate (IP3), D-myo-inositol 1,2,6-triphosphate (alpha-trinositol, PP 56, a novel Perstorp Pharma derivative), D-myo-inositol 1,3,4,5-tetraphosphate
E, Brailoiu +7 more
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Freeze-Anneal-Thaw Cycling of Unilamellar Liposomes: Effect on Encapsulation Efficiency
Pharmaceutical Research, 2013Freeze-thaw cycling is an important processing step in the preparation of liposomes that leads to the encapsulation of drug molecules. There is considerable variability in the number of freeze-thaw cycles reported in the literature. This work is designed to aid in liposomal formulation design by gaining an insight into the drug encapsulation process ...
Antonio P, Costa +2 more
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Preparation and Characterization of Glycolipid-Bearing Multilamellar and Unilamellar Liposomes
2003The carbohydrate residues of glycosphingolipids were implicated in many biologic processes such as cell-to-cell interactions; and as receptors for some viruses, bacterial and plant toxins, hormones, and so forth, and invariably for all the lectins (1). However, their receptor functions remained poorly defined for a long time as they form micelles even ...
Satish, PR, Surolia, Avadhesha
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Solubilization of phosphatidylcholine unilamellar liposomes caused by alkyl glucosides
Journal of Surfactants and Detergents, 1998AbstractSolubilizing alterations caused by a series of alkyl glucosides (alkyl chain lengths ranging from C8 to C12) in phosphatidylcholine (PC) unilamellar liposomes were investigated. Surfactant‐to‐phospholipid molar ratios (Re) and bilayer/aqueous phase partition coefficients (K) were determined by monitoring changes in static light scattering (SLS)
A. de la Maza +4 more
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Solubilization of unilamellar liposomes caused by quaternary ammonium surfactants
Journal of Controlled Release, 1995Abstract The mechanisms governing the solubilization of neutral and electrically charged liposomes by a series of quaternary ammonium surfactants (alkyl chain lengths C-12 (DoTAB), C-14 (TeTAB) and C-16 (HeTAB)) were investigated. Solubilization was detected as a decrease in static light scattering of liposome suspensions.
A. de la Maza, J.L. Parra
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