Results 141 to 150 of about 50,051 (221)

Global Health Security in an Era of Explosive Pandemic Potential [PDF]

, 2017
Pandemics pose a significant risk to security, economic stability, and development. Annualized expected losses from pandemics are estimated at $60 billion per year. Despite the certainty and magnitude of the threat, the global community has significantly
Ayala, Ana, Gostin, Lawrence O.
core   +1 more source

Structural mapping of polyclonal IgG responses to HA after influenza virus vaccination or infection

mBio
Cellular and molecular characterization of immune responses elicited by influenza virus infection and seasonal vaccination have informed efforts to improve vaccine efficacy, breadth, and longevity.
André Nicolás León, Alesandra J. Rodriguez, Sara T. Richey, Alba Torrents de la Pena, Rachael M. Wolters, Abigail M. Jackson, Katherine Webb, C. Buddy Creech, Sandra Yoder, Philip A. Mudd, James E. Crowe, Julianna Han, Andrew B. Ward   +12 more
doaj   +1 more source

Universal influenza vaccine [PDF]

Nature Immunology, 2015
openaire   +1 more source

Advances in Nucleic Acid Universal Influenza Vaccines

Vaccines
Currently, vaccination with influenza vaccines is still an effective strategy to prevent infection by seasonal influenza virus in spite of some drawbacks with them. However, due to the rapid evolution of influenza viruses, including seasonal influenza viruses and emerging zoonotic influenza viruses, there is an urgent need to develop broad-spectrum ...
Liang Xu, Weigang Ren, Qin Wang, Junwei Li   +3 more
openaire   +3 more sources

The Development of a Novel Broad-Spectrum Influenza Polypeptide Vaccine Based on Multi-Epitope Tandem Sequences

Vaccines
Background: Polypeptide vaccines have the potential to improve immune responses by targeting conserved and weakly immunogenic regions in antigens. This study aimed to identify and evaluate the efficacy of a novel influenza universal vaccine candidate ...
Song Zhao, Junhao Luo, Wenhui Guo, Li Li, Siyu Pu, Libo Dong, Wenfei Zhu, Rongbao Gao   +7 more
doaj   +1 more source

An In-Depth Look at Recent Influenza Seasons and Vaccine Effectiveness [PDF]

, 2013
This paper aims to present an in-depth exploration of immunology, the influenza virus, vaccination, and vaccination’s effectiveness with respect to influenza.
Ricci, Ariana
core   +1 more source

A "Prime and Deploy" Strategy for Universal Influenza Vaccine Targeting Nucleoprotein Induces Lung-Resident Memory CD8 T cells. [PDF]

Immune Netw, 2021
Chung H, Kim EA, Chang J.
europepmc   +1 more source

Universal influenza vaccine: the holy grail?

Expert Review of Vaccines, 2012
Influenza vaccines have been available since the 1950s and have seen increasingly wide use as public health authorities expanded recommendations. Recent events including shortages and avian influenza outbreaks have renewed interest in influenza vaccines, particularly improved vaccines.
openaire   +2 more sources

Exploring the Potential of T-Cells for a Universal Influenza Vaccine. [PDF]

Vaccines (Basel), 2020
Vijayanand S, Gomes KB, Gala RP, Uddin MN, D'Souza MJ.   +4 more
europepmc   +1 more source

Fusion Protein Consisting of Hemagglutinin Small Subunit and Truncated Nucleoprotein as a Universal Influenza Vaccine Candidate: Starting In-Silico Evaluation Toward In Vitro Expression.

J Pharm Bioallied Sci, 2023
Morshedi F, Nazeri E, Saleh M, Farahmand B.   +3 more
europepmc   +1 more source