Results 141 to 150 of about 1,612,376 (366)

Supplementary Figure 1 from Universal Cancer Peptide-Based Therapeutic Vaccine Breaks Tolerance against Telomerase and Eradicates Established Tumor [PDF]

, 2023
Magalie Dosset, Yann Godet, Charline Vauchy, Laurent Beziaud, Yu Chun Lone, Christine Sedlik, Christelle Liard, Émeline Levionnois, Bertrand Clerc, Federico Sandoval, Étienne Daguindau, Simon Wain–Hobson, Éric Tartour, Pierre Langlade‐Demoyen, Christophe Borg, Olivier Adotévi   +15 more
openalex   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

ASSESSMENT OF THE EFFECTIVENESS OF A UNIVERSAL VACCINE AGAINST AGRICULTURAL ANIMAL CHLAMIDIOSIS ON RABBITS

, 2021
В. В. Евстифеев, Ф.М. Хусаинов, S. Yakovlev, Г. И. Хусаинова, I.R. Akbashev, D.D. Morozova, D.D. Morozova   +6 more
openalex   +1 more source

A universal flu vaccine.

Acta Biochimica Polonica, 2014
Influenza is a global health concern. The single most effective way of protecting people against influenza infection and disease is vaccination. However, currently available vaccines against influenza induce only strain-specific immunity, and do not elicit long-lasting serum antibody titers.
Malgorzata, Kesik-Brodacka, Grazyna, Plucienniczak   +1 more
openaire   +3 more sources

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Supplementary Figure 2 from Peptide-Conjugated PAMAM Dendrimer as a Universal DNA Vaccine Platform to Target Antigen-Presenting Cells

, 2023
Pirouz Daftarian, Angel E. Kaifer, Wei Li, Bonnie B. Blomberg, Daniela Frasca, Felix Roth, Raquibul Chowdhury, Eric A. Berg, Jordan B. Fishman, Husain A. Al Sayegh, Patricia Blackwelder, Luca Inverardi, Víctor Pérez, Vance Lemmon, Paolo Serafini   +14 more
openalex   +1 more source

Human Papillomavirus (HPV) Vaccine: Attitudes, Behaviors, and Beliefs of At-Risk Women [PDF]

, 2008
Cervical cancer is primarily caused by human papillomavirus (HPV) and is the second most common cause of cancer-related mortality among women. Female college students may be at risk for contracting HPV based on their sexual behavior.
Caron, Rosemary M, Kispert, Elisabeth, McGrath, Robert J.   +2 more
core   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Manganese Mineralization of Pathogenic Viruses as a Universal Vaccine Platform. [PDF]

Adv Sci (Weinh), 2023
Shi PD, Xu YP, Zhu Z, Zhou C, Wu M, He Y, Zhao H, Liu L, Zhao L, Li XF, Qin CF.   +10 more
europepmc   +1 more source

A highly conserved WDYPKCDRA epitope in the RNA directed RNA polymerase of human coronaviruses can be used as epitope-based universal vaccine design

BMC Bioinformatics, 2014
BackgroundCoronaviruses are the diverse group of RNA virus. From 1960, six strains of human coronaviruses have emerged that includes SARS-CoV and the recent infection by deadly MERS-CoV which is now going to cause another outbreak.
Refat Sharmin, A. B. Islam
semanticscholar   +1 more source