Results 31 to 40 of about 1,612,376 (366)

Development of a Universal Epitope-Based Influenza Vaccine and Evaluation of Its Effectiveness in Mice

open access: yesVaccines, 2022
Vaccination is an effective and economically viable means of protection against the influenza virus, but due to rapid viral evolution, modern seasonal vaccines are not effective enough.
Ramil R. Mintaev   +4 more
doaj   +1 more source

Effectiveness of a universal vaccination program with an HPV quadrivalent vaccine in young Brazilian women

open access: hybridVaccine, 2021
Eliana Wendland   +7 more
openalex   +2 more sources

Influenza Vaccines toward Universality through Nanoplatforms and Given by Microneedle Patches

open access: yesViruses, 2020
Influenza is one of the top threats to public health. The best strategy to prevent influenza is vaccination. Because of the antigenic changes in the major surface antigens of influenza viruses, current seasonal influenza vaccines need to be updated every
Sijia Tang, Wandi Zhu, Bao-Zhong Wang
doaj   +1 more source

Universal influenza vaccines: Shifting to better vaccines [PDF]

open access: yesVaccine, 2016
Influenza virus causes acute upper and lower respiratory infections and is the most likely, among known pathogens, to cause a large epidemic in humans. Influenza virus mutates rapidly, enabling it to evade natural and vaccine-induced immunity. Furthermore, influenza viruses can cross from animals to humans, generating novel, potentially pandemic ...
Berlanda Scorza, Francesco   +2 more
openaire   +2 more sources

Salmonella enterica serovar Choleraesuis vector delivering a dual-antigen expression cassette provides mouse cross-protection against Streptococcus suis serotypes 2, 7, 9, and 1/2

open access: yesVeterinary Research, 2022
A universal vaccine protecting against multiple serotypes of Streptococcus suis is urgently needed to improve animal welfare and reduce the consumption of antibiotics.
Yu-an Li   +6 more
doaj   +1 more source

In silico design and immunoinformatics analysis of a universal multi-epitope vaccine against monkeypox virus

open access: yesPLoS ONE, 2023
Monkeypox virus (MPXV) outbreaks have been reported in various countries worldwide; however, there is no specific vaccine against MPXV. In this study, therefore, we employed computational approaches to design a multi-epitope vaccine against MPXV ...
Samira Sanami   +8 more
semanticscholar   +1 more source

M2e-Based Influenza Vaccines with Nucleoprotein: A Review

open access: yesVaccines, 2021
Discovery of conserved antigens for universal influenza vaccines warrants solutions to a number of concerns pertinent to the currently licensed influenza vaccines, such as annual reformulation and mismatching with the circulating subtypes.
Mei Peng Tan   +3 more
doaj   +1 more source

Will the public take a universal influenza vaccine?: the need for social and behavioral science research

open access: yesHuman Vaccines & Immunotherapeutics, 2020
Every influenza season, uptake of the flu vaccine falls short of the Healthy People 2020 goal of at least 70% of adults being vaccinated. Mixed methods research finds multiple factors associated with this phenomenon including misconceptions about the ...
Sandra Crouse Quinn, Amelia Jamison
doaj   +1 more source

Flagellin-Fused Protein Targeting M2e and HA2 Induces Innate and T-Cell Responses in Mice of Different Genetic Lines

open access: yesVaccines, 2022
Efficient control of influenza A infection can potentially be achieved through the development of broad-spectrum vaccines. Recombinant proteins incorporating conserved influenza A virus peptides are one of the platforms for the development of cross ...
Liudmila A. Stepanova   +7 more
doaj   +1 more source

Universal selenium nanoadjuvant with immunopotentiating and redox-shaping activities inducing high-quality immunity for SARS-CoV-2 vaccine

open access: yesSignal Transduction and Targeted Therapy, 2023
The COVID-19 pandemic still greatly threatens the public health worldwide and novel vaccines to highly effectively combat SARS- CoV-2 remains an unmet clinical need. However, redox imbalance in immune cells under extra stimulation by vaccine or pathogens
Haoqiang Lai   +7 more
semanticscholar   +1 more source

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