Results 71 to 80 of about 1,149,515 (356)
How “Universal” are Universal Precautions?
AMA Journal of Ethics, 2009 Guidelines to improve observance of universal precaution standards and reporting of needlestick injuries by medical students and resident physicians. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.
openaire +2 more sources
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
The Impossible Mission: Global Justice Movement against Transnational Organized Crime [PDF]
, 2012 This article argues that the best counterattack against globally oriented transnational organized crime (TOC) is by a global response. The contribution of participating states and the creation of a collective identity against TOC are both necessary. This
CAYLI, BARIS
core +3 more sources
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
, 2018 In this article, I elucidate two main strands of thought in the Swarthmore Lectures concerning the relationship between Liberal Quakerism, Christianity, and Universalism.
Randazzo, DanChristy
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SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Alien life matters: reflections on cosmopolitanism, otherness, and astrobiology [PDF]
, 2016 This is a synaptic paper that invites the reader to take a stroll on the edges of cross-disciplinary knowledge. We will walk the roads of anthropology, history, philosophy, astronomy and biology.
Novoa, Andre
core +3 more sources
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Is a Growing Middle Class Good for the Poor? Social Policy in a Time of Globalization [PDF]
, 2017 We examine the effect of the rise and evolution of the middle class on extreme poverty, using the World Bank's international poverty line of $1.90 per person per day in 2011 purchasing power parity (PPP)- adjusted terms.
Homi Kharas, Raj M. Desai
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