Results 41 to 50 of about 1,307,187 (251)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Localization over complex-analytic groupoids and conformal renormalization
, 2008 We present a higher index theorem for a certain class of etale one-dimensional complex-analytic groupoids. The novelty is the use of the local anomaly formula established in a previous paper, which represents the bivariant Chern character of a ...
Denis Perrot +2 more
core +4 more sources
Statistics of zero crossings in rough interfaces with fractional elasticity [PDF]
, 2017 We study numerically the distribution of zero crossings in one-dimensional elastic interfaces described by an overdamped Langevin dynamics with periodic boundary conditions.
Kolton, Alejandro Benedykt +2 more
core +4 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Convergence in law in the second Wiener/Wigner chaos [PDF]
, 2012 Let L be the class of limiting laws associated with sequences in the second Wiener chaos. We exhibit a large subset L_0 of L satisfying that, for any F_infinity in L_0, the convergence of only a finite number of cumulants suffices to imply the ...
Guillaume Poly +3 more
core +9 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Le marquis de Pombal et la politique scientifique du Portugal
Bulletin du Centre de Recherche du Château de Versailles, 2006 The educational reforms carried out by the Marquess of Pombal (1699–1782) in the middle of the eighteenth century are generally considered as one of the critical moments in the genesis of Portugal’s modern science policy.
Henrique Leitão
doaj +1 more source
Size-assortative mating in simultaneous hermaphrodites: an experimental test and a meta-analysis [PDF]
, 2015 Assortative mating by size has been argued to be widespread in the animal kingdom. However, the strength of size-assortative mating is known to vary considerably between species and the underlying mechanisms promoting this inter-specific variation remain
Alda, Maria del Pilar +8 more
core +4 more sources
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source