Results 61 to 70 of about 2,333 (148)

The Neural Correlates of Consciousness: A Spectral Exponent Approach to Diagnosing Disorders of Consciousness

Brain Sciences
Background/Objectives: Disorder of consciousness (DoC) poses diagnostic challenges due to behavioral assessment limitations. This study evaluates the spectral exponent (SE)—a neurophysiological biomarker quantifying the decay slope of ...
Ying Zhao, Anqi Wang, Weiqiao Zhao, Nantu Hu, Steven Laureys, Haibo Di   +5 more
doaj   +1 more source

Advances in the neurorehabilitation of severe disorder of consciousness

Annali dell'Istituto Superiore di Sanità, 2014
Introduction. The paper describes the evolution of knowledge concerning severe brain injury which determines the Vegetative State/Unresponsive Wakefulness Syndrome. Background. The term Vegetative State was proposed by Jennet and Plum in 1972.
Giuliano Dolce, Lucia Francesca Lucca, Francesco Riganello, Francesco Arcuri, Maria Quintieri, Maria Daniela Cortese, Loris Pignolo   +6 more
doaj   +1 more source

Fetal Pain Perception: Legislative Assertions and Developmental Neuroscience

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Pain perception is a conscious experience, but neither pain nor consciousness is defined in the developing human fetus. Emergent consciousness may be regarded as a phenomenon that ultimately arises from an essential minimum of functional neuronal connectivity. Proposed U.S.
William D. Graf, Timothy M. Crombleholme, Leon G. Epstein, Dawn Gano, Phillip L. Pearl, Timothy V. Salomons, Mark S. Scher, Elise Turk, Klaus‐Peter Zimmer, Harvey B. Sarnat   +9 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Homeostatic plasticity in patients with disorders of consciousness detected by combined stimulation: a study protocol

Frontiers in Neurology
BackgroundNon-invasive neuromodulation (NIN) techniques have been widely utilized in treating patients with disorders of consciousness (DoC), but their therapeutic effects have been inconsistent.
Jingwen Wang, Jingwen Wang, Fangfang Shou, Qiuyi Yu, Xulan Lu, Yuwen Wan, Yuwen Wan, Wangshan Huang, Nantu Hu, Zhenyi Jin, Xinru Shan, Steven Laureys, Steven Laureys, Haibo Di   +13 more
doaj   +1 more source

Exploring end-of-life decision-making in China for disorders of consciousness

Annals of Medicine
Objectives We aim to investigate the ethical attitudes of the Chinese population toward withdrawal of life-sustaining treatment (WLST) in disorders of consciousness (DoC) patients.Methods A self-administered questionnaire concerning WLST was distributed ...
Meiqi Li, Benedetta Cecconi, Olivia Gosseries, Lijuan Cheng, Yifan Yan, Yan Chen, Yan Li, Steven Laureys, Haibo Di   +8 more
doaj   +1 more source

Global White Matter Damage in Focal Brainstem Injury Patients With Disorders of Consciousness: A Diffusion Tensor Tractography Study

European Journal of Neurology, Volume 33, Issue 1, January 2026.
ABSTRACT Background Disorders of consciousness (DoC) pose significant challenges in clinical diagnosis and treatment. This study aims to investigate the relationship between consciousness levels and the brainstem‐cortical white matter tracts in DoC patients resulting from focal brainstem injury using diffusion tensor imaging (DTI).
Miao Wang, Qiheng He, Sipeng Zhu, Tianqing Cao, Nan Wang, Yitong Jia, Hongbin Wu, Jianfeng Liang, Hongchuan Niu, Zongsheng Xu, Zaixu Cui, Yi Yang, Jizong Zhao   +12 more
wiley   +1 more source

A practical guide to the updated seizure classification 2025

Epileptic Disorders, Volume 27, Issue 6, Page 1087-1104, December 2025.
Abstract This paper provides a practical guide to applying the updated seizure classification in clinical settings. The updated classification, published by the International League Against Epilepsy in 2025, builds on the operational classification introduced in 2017.
Sándor Beniczky, Eugen Trinka, Elaine Wirrell, Mamta Bhushan Singh, Hal Blumenfeld, Alicia Bogacz Fressola, Fernando Cendes, Dana Craiu, Birgit Frauscher, Floor E. Jansen, Philippe Kahane, Veena Kander, Nirmeen Kishk, Ching Soong Khoo, Angelica Lizcano, Luca De Palma, Philippe Ryvlin, Nicola Specchio, Michael R. Sperling, William Tatum, Elza Márcia Yacubian, Jo Wilmshurst, J. Helen Cross   +22 more
wiley   +1 more source

Perception of diagnosis by family caregivers in severe brain injury patients in China

BMC Palliative Care
Objectives Surrogate decision-making by family caregivers for patients with severe brain injury is influenced by the availability and understanding of relevant information and expectations for future rehabilitation. We aimed to compare the consistency of
Yifan Yan, Meiqi Li, Jitka Annen, Wangshan Huang, Tiantian Cai, Xueying Wang, Xiaohua Hu, Steven Laureys, Haibo Di   +8 more
doaj   +1 more source

Heart Rate Variability Response to Therapist‐Selected Music as a Diagnostic Biomarker for Disorders of Consciousness

Sensory Neuroscience, Volume 1, Issue 3, December 2025.
Music modulates autonomic pathways to alter heart rate variability (HRV), with therapist‐selected music (TSM) showing the strongest association with consciousness levels in patients with disorders of consciousness (DOC). ABSTRACT Music, as an auditory stimulus, has long been recognized for its ability to evoke heart rate variability (HRV) responses. In
Jiajia Kang, Haidi Wu, Ling Wang, Xiaodan Tan, Yun Wen, Feng Yang, Qiuyou Xie, Chang'an A. Zhan   +7 more
wiley   +1 more source