Results 161 to 170 of about 3,744,358 (305)

Comparative metabolomics of high-unsaturated fatty acid oils: exploring volatile and nonvolatile metabolite differences in olive, walnut, flaxseed, and camellia oils. [PDF]

Front Nutr
Zhang B, Chen Z, Qin K, Yang Y, Xu L, Zhang Z.   +5 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Formation of hierarchical supramolecular microstructures from 6-<i>O</i>-alkylated α-cyclodextrin and their application to the selective extraction of long-chain unsaturated fatty acid esters. [PDF]

RSC Adv
Ishida H, Miyakawa S, Shigemitsu H, Fukuzawa K, Kida T.   +4 more
europepmc   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

Opium trade and use during the Late Bronze Age: Organic residue analysis of ceramic vessels from the burials of Tel Yehud, Israel

Archaeometry, EarlyView., 2022
Abstract Organic residue analysis was conducted on various vessels from burials at Tel Yehud, Israel. The analyses led to new reliable evidence for the presence of opioid alkaloids and their decomposition products. This research revitalizes a decades‐old discussion on the presence and function of the opium trade across a cultural region of utmost ...
Vanessa Linares, Eriola Jakoel, Ron Be’eri, Oded Lipschits, Ronny Neumann, Yuval Gadot   +5 more
wiley   +1 more source

Association Between Unsaturated Fatty Acid Levels and Chronic Obstructive Pulmonary Disease: A Bidirectional Mendelian Randomization Study. [PDF]

Clin Respir J
Jiang S, Lu L, Wang X, Zhu X, Chen X, Chang HC, Gu X, Yang F, Liu X, Zhang X, Shen X.   +10 more
europepmc   +1 more source

Biochemical and Molecular Insights Into Monocrotaline‐Induced Hepatotoxicity: An Experimental Mouse Study

Journal of Applied Toxicology, EarlyView.
ABSTRACT Monocrotaline (MCT), a plant‐derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT‐induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemical, molecular, and ...
Ali Şenol, Alparslan Kadir Devrim, Miyase Çinar, Mahmut Sözmen, Fatma Betül Akça   +4 more
wiley   +1 more source

Unsaturated Fatty Acid Metabolic Reprogramming in Psoriatic Skin Drives Inflammation and Predicts Response to Biologic Therapy. [PDF]

Clin Cosmet Investig Dermatol
Miao H, Guan X, Li L, Wang L, Luo Y.
europepmc   +1 more source

Assessing Metabolic and Reproductive Consequences of Prenatal Paracetamol Exposure in Female CD1 Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Paracetamol is a widely used analgesic during pregnancy; however, emerging evidence suggests it may act as an endocrine/metabolism disrupting compound. Using an F1 female CD1 mouse model, this study scrutinized the long‐term metabolic and reproductive consequences linked to intrauterine paracetamol exposure.
Bita Entezari, Deniz Bozdag, Elif İnce‐Erguc, Aylin Buhur, Cansin Sirin Tomruk, Suna Sabuncuoglu, Altug Yavasoglu, Hande Gurer‐Orhan   +7 more
wiley   +1 more source

GuiLingJi ameliorates mild cognitive impairment by targeting unsaturated fatty acid metabolism to inhibit GPR120/NF-κB mediated neuroinflammation. [PDF]

Front Pharmacol
Shi J, Ni L, Yu S, Gao X, Qin X.
europepmc   +1 more source