Results 61 to 70 of about 3,744,358 (305)

Stimulation of OGG1 Enhances Oxidative DNA Damage Repair and Protects Against Acute Liver Failure by Acetaminophen

Advanced Science, EarlyView.
Chemical switching of OGG1 by CMM‐98 accelerates oxidative DNA damage repair and enhances hepatocyte resilience during acetaminophen‐induced acute liver injury. By promoting efficient processing of OGG1‐generated repair intermediates, CMM‐98 reduces oxidative damage, preserves cellular integrity, and protects against acute liver failure, identifying ...
Zhenjun Zhao, Rahul Upadhyay, Alice Eddershaw, Chenchen Wang, Yudong Zhao, Olov Wallner, Jinhye Ryu, Nayere Taebnia, Heather Gildie, Emma Scaletti‐Hutchinson, Jonathan R. Davies, Nicole Ziegler, Andreas Krämer, Samantha C. Robinson, Marek Varga, Karolina Singerova, Zuzanna Szaruga, Elisée Wiita, İrşil Güneş, Sheila S. David, Stefan Knapp, Aimo Kannt, Miguel de Vega, Pål Stenmark, Volker M Lauschke, Maurice Michel   +25 more
wiley   +1 more source

Determination of Fatty Acid in Asparagus by Gas Chromatography

İstanbul Üniversitesi Veteriner Fakültesi Dergisi, 2016
Asparagus contain a lot of macronutrients and micronutrients including folate, dietary fibre (soluble and insoluble) and phenolic compounds. Also asparagus is a good source of unsaturated linoleic and linolenic fatty acids which are precursors for ...
Zehra HAJRULAI-MUSLIU, Risto UZUNOV, Biljana STOJANOVSKA-DIMZOSKA, Elizabeta DIMITRIEVSKA-STOJKOVIC, Aleksandra ANGELEVSKA, elimir STOJKOVSKI   +5 more
doaj   +1 more source

Fatty acid desaturation in lung: inhibition by unsaturated fatty acids

Journal of Lipid Research, 1980
The activity of the enzyme system involved in desaturation of palmitic and stearic acid has been examined in lungs of rats fed fat-free diets supplemented either with 4% safflower oil (controls) or 4% tripalmitin (essential fatty acid (EFA) deficient) both in vivo and in vitro in lung slices.
J A Balint, E C Kyriakides, D A Beeler
openaire   +3 more sources

Determination of chlorinated fatty acids using SPE, XSD and GC/MS [PDF]

, 2004
Chlorinated fatty acids (ClFAs) account for a considerable portion of the extractable, organically bound chlorine (EOCl) in aquatic animals. Because of analytical difficulties little is as of yet known about their behaviour in organisms.
Åkesson-Nilsson, Gunilla
core   +1 more source

Effects of fat source and dietary sodium bicarbonate plus straw on the conjugated linoleic acid content of milk of dairy cows [PDF]

, 2007
The effects of fat source (0.7 kg of fatty acids from extruded soybeans or palmitic acid), of sodium bicarbonate (0.3 kg) plus straw (1 kg) and the interaction of these treatments on the content of conjugated linoleic acid (CLA) in the milk of dairy cows
Troegeler-Meynadier, Annabelle, Nicot, Marie-Claude, Enjalbert, Francis   +2 more
core   +1 more source

Lipid Metabolic Dysregulation Driven by OSMR Mutations Underlies Amyloidogenesis in Primary Localized Cutaneous Amyloidosis

Advanced Science, EarlyView.
OSMR mutations disrupt STAT5 signaling and AKR1B10‐mediated lipid metabolism, leading to lipid accumulation and protein aggregation in keratinocytes. This metabolic reprogramming drives amyloid deposition in primary localized cutaneous amyloidosis, revealing a mechanistic link between lipid dysregulation and amyloidogenesis.
Huiting Liu, Wen Zheng, Chao Yang, Tao Yang, Qiuyu Chen, Ping Lu, Huan Yang, Jun Liu, Bin Yang   +8 more
wiley   +1 more source

Long chain saturated and unsaturated fatty acids exert opposing effects on viability and function of GLP-1-producing cells: Mechanisms of lipotoxicity. [PDF]

PLoS ONE, 2017
BACKGROUND AND AIM:Fatty acids acutely stimulate GLP-1 secretion from L-cells in vivo. However, a high fat diet has been shown to reduce the density of L-cells in the mouse intestine and a positive correlation has been indicated between L-cell number and
Ketan Thombare, Stelia Ntika, Xuan Wang, Camilla Krizhanovskii   +3 more
doaj   +1 more source

Three-year tracking of fatty acid composition of plasma phospholipids in healthy children [PDF]

, 2007
Objectives: The fatty acid composition of plasma phospholipids reflects the dietary fatty acid intake as well as endogenous turnover. We aimed at investigating the potential tracking of plasma phospholipid fatty acid composition in children that ...
Toschke, Andre Michael, Guerra, Antonio, Koletzko, Berthold, Demmelmair, Hans   +3 more
core   +1 more source

A Postbiotic‐Inducing Ganoderma applanatum Polysaccharide Repairs the Intestinal Barrier via a Phocaeicola vulgatus ‐ Tridecylic Acid Axis

Advanced Science, EarlyView.
This study identifies GAP2, a bioactive polysaccharide fraction derived from Ganoderma applanatum, as a postbiotic inducer that repairs intestinal barrier damage in a gut microbiota‐dependent manner. GAP2 enriches Phocaeicola vulgatus, which degrades GAP2 and promotes tridecylic acid production, triggering Rho/CDC42 signaling and tight‐junction ...
Chuan Zhang, Miaoyu Li, Tiantian Li, Xiaojie Zang, Haiyang Shi, Yaru Liu, Chengcheng Zhang, Jianxin Zhao, Qixiao Zhai, Wei Chen, Fengwei Tian   +10 more
wiley   +1 more source

Process For The Production Of Delta5-unsaturated Fatty Acids In Transgenic Organisms (Patent EP 2388332 A1) [PDF]

, 2011
A process for the production of ”5-unsaturated fatty acids in transgenic organisms comprises transforming an organism with nucleic acid encoding a ”5 ...
Zank, T., Sayanova, O. V., Napier, J. A.
core