Results 141 to 150 of about 100,487 (260)

Harnessing microbial metabolism and nutrition to target the gut–mammary axis for better livestock production and health

open access: yesiMetaOmics, EarlyView.
The gut–mammary axis integrates intestinal health with mammary function through neural, endocrine, and immune pathways. Nutritional interventions (probiotics, prebiotics, metabolites) improve gut microecology, generating microbial signals that travel via the axis to the mammary gland. There, they relieve inflammation, enhance milk quality and lactation,
Aolong Zhou   +29 more
wiley   +1 more source

Unsaturated Fatty Acids Are Decreased in Aβ Plaques in Alzheimer's Disease. [PDF]

open access: yesJ Neurochem
Röhr D   +5 more
europepmc   +1 more source

Limosilactobacillus reuteri enhances ovarian function and female fertility

open access: yesiMeta, EarlyView.
Limosilactobacillus reuteri Y15 (LRY15)‐derived polyunsaturated fatty acids (PUFAs) restore follicular cell‐cell junctions and fertility. LRY15, isolated from the intestine of alginate oligosaccharides (AOS)‐dosed mice, improves ovarian function and fertility in cisplatin‐induced subfertile mice.
Yongsheng Hao   +22 more
wiley   +1 more source

A Longitudinal Study of the Association of Blood Unsaturated Fatty Acids With Posttraumatic Stress Disorder (PTSD). [PDF]

open access: yesNeuropsychopharmacol Rep
Inoue T   +9 more
europepmc   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

open access: yesInterdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu   +6 more
wiley   +1 more source

Accumulation of long-chain unsaturated fatty acids in the airway inflammatory microenvironment drives eosinophil etosis and corticosteroid resistance. [PDF]

open access: yesCell Commun Signal
Bai Y   +15 more
europepmc   +1 more source

Mitochondria‐targeted nanomedicine for cancer therapy: Targeting strategies, therapeutic mechanisms, and translational challenges

open access: yesInterdisciplinary Medicine, EarlyView.
This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao   +7 more
wiley   +1 more source

On the Origin of Unsaturated Fatty Acids in Clostridia

open access: yesJournal of Biological Chemistry, 1961
H, GOLDFINE, K, BLOCH
openaire   +2 more sources

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