Results 231 to 240 of about 56,044 (294)

Colorectal Precancerous Lesions: Molecular Mechanisms, Research Tools, and Natural Product‐Based Clinical Translation

MedComm – Oncology, Volume 5, Issue 2, June 2026.
This article systematically elucidates the molecular mechanisms of colorectal precancerous lesions, introduces cutting‐edge research tools like multi‐omics and organoids, and highlights the potential and prospects of natural products such as berberine, resveratrol, and curcumin in preventing and intervening in colorectal carcinogenesis by modulating ...
Shunji Liu, Chujuan Cui, Lingdong Kong, Qiang Xu, Haibo Cheng, Lisha Zhou, Yang Sun   +6 more
wiley   +1 more source

A resource to empirically establish drug exposure records directly from untargeted metabolomics data. [PDF]

Nat Commun
Zhao HN, Kvitne KE, Brungs C, Mohan S, Charron-Lamoureux V, Bittremieux W, Tang R, Schmid R, Lamichhane S, Xing S, El Abiead Y, Andalibi MS, Mannochio-Russo H, Ambre M, Avalon NE, Bryant M, Burnett LA, Caraballo-Rodríguez AM, Maya MC, Chin L, Corominas L, Ellis RJ, Franklin D, Girod S, Gomes PWP, Hansen L, Heaton RK, Iudicello JE, Jarmusch AK, Khatib L, Letendre S, Magyari S, McDonald D, Mohanty I, Cumsille A, Moore DJ, Rajkumar P, Ross DH, Sapre H, Shahneh MRZ, Gil-Solsona R, Thomas SP, Tribelhorn C, Tubb HM, Walker C, Wang CX, Zemlin J, Zuffa S, Wishart DS, Gago-Ferrero P, Kaddurah-Daouk R, Wang M, Raffatellu M, Zengler K, Pluskal T, Xu L, Knight R, Tsunoda SM, Dorrestein PC.   +58 more
europepmc   +1 more source

Sensory Assessment of Pressure‐Cooked and Pureed Faba Bean Cultivars: The Contribution of Cotyledon and Seed Coat Constituents Toward the Perception of Sensory Attributes

Sustainable Food Proteins, Volume 4, Issue 2, June 2026.
Whole beans and cotyledons from three faba bean cultivars, Malik, Fabelle, and Snowbird, were processed into purees through a sequence of soaking, blanching, hot filling, pressure cooking, and blending. Purees prepared from whole beans were centrifuged, and the supernatants were collected. A trained sensory panel evaluated the aroma, flavor, taste, and
Claire M. Chigwedere, Lamia L'Hocine, Janitha P. D. Wanasundara, Phyllis J. Shand   +3 more
wiley   +1 more source

Discovery of newborn Wilson disease biomarkers via integrated next-generation sequencing and untargeted metabolomics. [PDF]

Orphanet J Rare Dis
Guan X, Sun Y, Wang Y, Li Y, Zhang Z, Hong D, Yang P, Liang X, Wang X, Yu B.   +9 more
europepmc   +1 more source

Wheat's war against stripe rust: Integrating host immunity, genomics and breeding for durable resistance

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Wheat (Triticum aestivum L.), a foundation of global food security, faces persistent threats from stripe rust caused by Puccinia striiformis f. sp. tritici (Pst). The pathogen thrives in cool and humid environments and regularly causes epidemics that lead to severe yield losses.
Farkhandah Jan, Mukesh Rathore, Dinesh Kumar Saini, Ayushi Singh, Naeela Qureshi, Nikita Aggarwal, Mahpara Bashir, Mehnaz Shakeel, Vikas Gupta, Sundeep Kumar, Rajeev Kumar Varshney, Reyazul Rouf Mir   +11 more
wiley   +1 more source

Hydroxytyrosol Modulates Arachidonic Acid Metabolism and Purine Catabolism in Individuals with Prediabetes: An Untargeted Metabolomics Study in a Randomized Controlled Trial. [PDF]

Antioxidants (Basel)
Moratilla-Rivera I, Fernández-Millán E, Pérez-Jiménez J, Ramos S, Yanes Ó, Capellades J, Mateos R, Martín MÁ.   +7 more
europepmc   +1 more source

Temporal Metabolomics Profiling Reveals Liver Metabolic Control in Single and Repeated Exhaustive Exercise in Murine Models

The FASEB Journal, Volume 40, Issue 9, 15 May 2026.
Temporal metabolomics profiling reveals divergent liver recovery trajectories between single and repeated exhausted exercise stress. Single exhaustive exercise (SEE) demonstrates transient metabolic perturbations resolving within 24 h. In contrast, repeated exhaustive exercise (REE) triggers sustained metabolic remodeling that persists beyond the ...
Jining Yang, Dawei Wang, Hui Shen, Yundong Xia, Hedong Lang, Wenxin Zhou, Long Yi, Mantian Mi   +7 more
wiley   +1 more source

Dissecting Metabolic Rewiring and Gene-Metabolite Interactions by Utilizing Untargeted Metabolomics and Single-Gene Knockouts in the Model Microorganism <i>E. coli</i>. [PDF]

J Am Soc Mass Spectrom
Pang X, Chen L, Zhang H, Zhang S, Zhu J.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, Volume 16, Issue 5, Page 906-920, May 2026.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source