Results 1 to 10 of about 162,571 (289)

The ODC 3′-Untranslated Region and 5′-Untranslated Region Contain cis-Regulatory Elements: Implications for Carcinogenesis [PDF]

Medical Sciences, 2017
It has been hypothesized that both the 3′-untranslated region (3′UTR) and the 5′-untranslated region (5′UTR) of the ornithine decarboxylase (ODC) mRNA influence the expression of the ODC protein.
Shannon L. Nowotarski, Lisa M. Shantz
doaj   +3 more sources

Importance of the 5’ untranslated region for recombinant enzyme production in isolated Bacillus subtilis 007 [PDF]

AMB Express
The production of industrial enzymes requires an efficient expression system with a suitable host. This study investigated the isolated Bacillus subtilis 007 as a host for expressing three enzymes with potential application in the food industry. Firstly,
Jana Senger, Adriana Schulz, Ines Seitl, Martin Heider, Lutz Fischer   +4 more
doaj   +2 more sources

Optimization of the 5ʹ untranslated region of mRNA vaccines [PDF]

Scientific Reports
To investigate the impact of different 5ʹ untranslated regions (UTRs) on mRNA vaccine translation efficiency, five dual-reporter gene expression plasmids with different 5ʹUTRs were constructed.
Qi Ma, Xiaoguang Zhang, Jing Yang, Hongxia Li, Yanzhe Hao, Xia Feng   +5 more
doaj   +2 more sources

Mapping the Pax6 3’ untranslated region microRNA regulatory landscape

BMC Genomics, 2018
Background PAX6 is a homeodomain transcription factor that acts in a highly dosage-sensitive manner to regulate the development and function of the eyes, nose, central nervous system, gut, and endocrine pancreas. Several individual microRNAs (miRNA) have
Bridget C. Ryan, Kieran Lowe, Laura Hanson, Talveen Gil, Lauren Braun, Perry L. Howard, Robert L. Chow   +6 more
doaj   +3 more sources

Dissecting the Conformational Heterogeneity of Stem-Loop Substructures of the Fifth Element in the 5'-Untranslated Region of SARS-CoV-2. [PDF]

J Am Chem Soc
Mertinkus KR, Oxenfarth A, Richter C, Wacker A, Mata CP, Carazo JM, Schlundt A, Schwalbe H.   +7 more
europepmc   +3 more sources

Internal ribosomal entry site-mediated translational activity of nitric oxide synthase 2

Animal Cells and Systems, 2023
The internal ribosome entry site (IRES) is a unique structure found in the 5’ untranslated region (5'-UTR) of specific messenger RNAs (mRNAs) that allows ribosomes to bind and initiate translation without the need for a cap structure.
Kyung-Ha Lee
doaj   +1 more source

The 5′ and 3′ Untranslated Regions of the Japanese Encephalitis Virus (JEV): Molecular Genetics and Higher Order Structures

Frontiers in Microbiology, 2021
The untranslated region (UTRs) of viral genome are important for viral replication and immune modulation. Japanese encephalitis virus (JEV) is the most significant cause of epidemic encephalitis worldwide.
Hong Liu, Hong Liu, Jun Zhang, Yuzhen Niu, Guodong Liang   +4 more
doaj   +1 more source

Post-Transcriptional Regulation of Immune Responses and Inflammatory Diseases by RNA-Binding ZFP36 Family Proteins

Frontiers in Immunology, 2021
Post-transcriptional regulation is involved in the regulation of many inflammatory genes. Zinc finger protein 36 (ZFP36) family proteins are RNA-binding proteins involved in messenger RNA (mRNA) metabolism pathways. The ZFP36 family is composed of ZFP36 (
Sohei Makita, Hiroaki Takatori, Hiroaki Takatori, Hiroshi Nakajima   +3 more
doaj   +1 more source

Conserved Sequences in the 5′ and 3′ Untranslated Regions of Jingmenvirus Group Representatives

Viruses, 2023
The Jingmenvirus group (JVG), with members such as Jingmen tick virus (JMTV), Alongshan virus (ALSV), Yanggou tick virus (YGTV), and Takachi virus (TAKV), is drawing attention due to evidence of it causing disease in humans and its unique genome ...
Alexander G. Litov, Egor V. Okhezin, Ivan S. Kholodilov, Oxana A. Belova, Galina G. Karganova   +4 more
doaj   +1 more source

Characterization and optimization of 5´ untranslated region containing poly-adenine tracts in Kluyveromyces marxianus using machine-learning model. [PDF]

Microb Cell Fact
Zeng J, Song K, Wang J, Wen H, Zhou J, Ni T, Lu H, Yu Y.   +7 more
europepmc   +3 more sources