Results 101 to 110 of about 25,321,967 (307)

Prenatal Exposure to Methamphetamine: Up-Regulation of Brain Receptor Genes

open access: yesFrontiers in Neuroscience, 2019
Methamphetamine (METH) is a widespread illicit drug. If it is taken by pregnant women, it passes through the placenta and just as it affects the mother, it can impair the development of the offspring.
Hana Zoubková   +4 more
doaj   +1 more source

Resveratrol induces chemosensitization to 5-fluorouracil through up-regulation of intercellular junctions, Epithelial-to-mesenchymal transition and apoptosis in colorectal cancer.

open access: yesBiochemical Pharmacology, 2015
5-Fluorouracil (5-FU), a common chemotherapeutic agent used for the treatment of colorectal cancer (CRC), by itself has inadequate response rates; highlighting the need for novel and improved treatment regimens for these patients.
Constanze Buhrmann   +5 more
semanticscholar   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Discretionary Investing by ‘Passive’ S&P 500 Funds

open access: yes
This page contains the code and data necessary to replicate the results of "Discretionary Investing by ‘Passive’ S&P 500 Funds" by Peter Molk & Adriana Z. Robertson, published in the Yale Journal on Regulation (2024)
Journal on Regulation, Yale
core   +1 more source

Up-regulation of circulating C19MC microRNAs in pregnancies destined to developed preeclampsia.

open access: yes, 2017
Up-regulation of circulating C19MC microRNAs in pregnancies destined to developed preeclampsia.
Ilona Hromadnikova (674808)   +3 more
core   +1 more source

Up-regulation of CD44 in the development of metastasis, recurrence and drug resistance of ovarian cancer

open access: yesOncoTarget, 2015
The clinical significance of Cluster of Differentiation 44 (CD44) remains controversial in human ovarian cancer. The aim of this study is to evaluate the clinical significance of CD44 expression by using a unique tissue microarray, and then to determine ...
Yan Gao   +8 more
semanticscholar   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Beyond Kyoto. The initial experience with the EU Emission Trading Scheme and the prospects for a global change strategy after 2012 [PDF]

open access: yes, 2007
The Florence School of Regulation organised a workshop on ‘Beyond Kyoto. The initial experience with the EU Emission Trading Scheme and the prospects for a global climate strategy after 2012’ on 20 October 2006 at the European University Institute in ...
Florence School of Regulation
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Regulation of mark-up on medicine prices in Zimbabwe: a pilot survey from 92 community pharmacies in the metropolitan area of Harare

open access: yesHealth Economics Review
Background Medicine pricing in the community pharmacy sector in Zimbabwe significantly influences accessibility to health care. In this pilot survey, we investigated how community pharmacies in Zimbabwe apply various mark-up strategies to essential and ...
Hilma N Nakambale   +2 more
doaj   +1 more source

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