Results 181 to 190 of about 36,901 (236)

Comparing Deep Learning Models for Identifying Maxillary Transverse Deficiency from Intraoral Photographs. [PDF]

Int Dent J
Li J, Wang R, Yi Z, Ni J, Zuo Z, Wang Y.
europepmc   +1 more source

The Urokinase Receptor (uPAR, CD87) as a Target for Tumor Therapy: uPA-Silica Particles (SP-uPA) as a New Tool for Assessing Synthetic Peptides to interfere with uPA/uPA-Receptor Interaction

, 2003
Many different processes in the physiology and pathophysiology of human beings are regulated protein/protein interactions such as receptor/ligand interactions. A more detailed knowledge of the nature of receptor/ligand binding sites and mechanisms of interaction is necessary as well in order to understand the process of cancer spread and metastasis ...
Elke, Guthaus, Niko, Schmiedeberg, Markus, Bürgle, Viktor, Magdolen, Horst, Kessler, Manfred, Schmitt   +5 more
openaire   +3 more sources

Inhibition of Human Urokinase-Type Plasminogen Activator (uPA) Enzyme Activity and Receptor Binding by DNA Aptamers as Potential Therapeutics Through Binding to the Different Forms of uPA

International Journal of Molecular Sciences, 2022
Urokinase-type plasminogen activator is widely discussed as a marker for cancer prognosis and diagnosis and as a target for cancer therapies. Together with its receptor, uPA plays an important role in tumorigenesis, tumor progression and metastasis.
Marcus Menger, Wiebke Sabrowski, Nico Dreymann   +2 more
exaly   +2 more sources

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The uPA/uPA receptor system as a target for tumor therapy

Drug News & Perspectives, 2001
Invasiveness of a variety of tumors depends on the regulated expression of proteolytic enzymes that degrade the surrounding extracellular matrix and dissociate cell-cell and/or cell-matrix attachments. The tumor cell surface-associated urokinase-type plasminogen activator (uPA) system plays an especially important role in tumor cell invasion and ...
S, Sperl, M M, Mueller, O G, Wilhelm, M, Schmitt, V, Magdolen, L, Moroder   +5 more
openaire   +2 more sources

uPA/PAI-1 expression and uPA promoter methylation in meningiomas

Journal of Neuro-Oncology, 2010
The extent of resection and the intrinsic biological aggressiveness of the tumor have been repeatedly identified as the primary determinants of meningioma recurrence. Invasive growth limits the resectability of meningiomas. Tumor invasion is mediated by matrix metalloproteases and their inhibitors such as uPA and PAI-1.
Julia Annabel, Kandenwein, Tjoung-Won, Park-Simon, Johannes, Schramm, Matthias, Simon   +3 more
openaire   +2 more sources

Changes of uPA and uPA-R expression in the cornea after alkali burn

Colloids and Surfaces B: Biointerfaces, 2004
To investigate the expression levels of uPA and uPA-R in corneal repair after alkali burn.The corneal alkali burn models were established in vitro and in vivo, then immunocytochemistry (ICC) of uPA/uPA-R and image analysis and statistical evaluation were performed to determine their expression levels both in vitro and in vivo.Compared with control ...
Jun, Yan, Tian, Yang, Guoping, Li, Yi, Zhang, Yijun, Zeng, Jin, Yang   +5 more
openaire   +2 more sources

The UPA score and teenage pregnancy

Public Health, 1993
Teenage motherhood is often said to be the result of deficient contraceptive and abortion services. Using data from the Public Health Common Data Set (PH CDS) we demonstrate two important effects in a Regional Health Authority: higher rates of conception are related to a live birth rather than an abortion pregnancy outcome; District Health Authorities (
R, Garlick, B, Ineichen, F, Hudson
openaire   +2 more sources

UPA Arbeitskreis The Positive X

2019
Als UX Professionals haben wir die Chance zur positiven Neugestaltung von Freizeit-und Arbeitswelten. Der Arbeitskreis „The Positive X“ widmet sich diesem Thema und den Fragen: Was macht das Leben lebenswert? Wie schaffen wir freudvolle und bedeutsame Erlebnisse sowie Wohlbefinden durch Technologie?
Cristina Hermosa Perrino, Katharina M. Zeiner, Michael Burmester 0001   +2 more
openaire   +1 more source

uPA/PAI-1 expression and uPA promoter methylation in meningiomas

2009
Objective: The degree of resection and the intrinsic biological aggressiveness of the tumor have been repeatedly identified as the primary determinants of meningioma recurrence. Invasive growth limits the resectability of meningiomas. Brain invasion has been included as a grading criterion into the [for full text, please go to the a.m. URL]
Kandenwein, J, Park-Simon, TW, Mahlberg, R, Schramm, J, Simon, M   +4 more
openaire   +1 more source