Results 1 to 10 of about 35 (28)
Human uracil DNA N-glycosidase: studies in normal and repair defective cultured fibroblasts [PDF]
Nucleic Acids Research, 1978 Uracil DNA N-glycosidase, an enzyme which participates in the excision of uracil from DNA, was measured in extracts from fibroblasts lines cultured from normal subjects, from several subjects with the genetic disease xeroderma pigmentosum, and from a subject with ataxia telangiectasia.
Urs Kuhnlein, Stuart Linn, Betty Lee
openaire +5 more sources
Enzymes from Micrococcus luteus involved in the initial steps of excision repair of spontaneous DNA lesions: uracil-DNA-glycosidase and apurinic-endonucleases [PDF]
Nucleic Acids Research, 1978 Uracil-DNA-glycosidase that releases free uracil from single-stranded or double-stranded deaminated DNA and poly d(A-U) has been partially purified from Micrococcus luteus. The enzyme has a molecular weight of about 16,000 and can be separated from uracil-endonuclease and endonucleases (AP-endonucleases) specific for apurinic and apyrimidinic sites ...
L.S. Barenfeld +2 more
openaire +5 more sources
DNA N-glycosidases: properties of uracil-DNA glycosidase from Escherichia coli.
Journal of Biological Chemistry, 1977 Tomas Lindahl +4 more
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APOBEC3G protects the genome of human cultured cells and mice from radiation‐induced damage
The FEBS Journal, Volume 290, Issue 7, Page 1822-1839, April 2023., 2023 A3G protects mice from IR‐induced damage and promotes accurate DNA double‐strand breaks repair in cultured cells. Transgenic mice expressing A3G successfully survived lethal irradiation, whereas wild‐type controls quickly succumbed to radiation syndrome.
Yelena Britan‐Rosich +11 more
wiley +1 more source
European Journal of Organic Chemistry, Volume 26, Issue 4, January 24, 2023., 2023 In this review, the potential of carbohydrates as starting materials for the synthesis of antimicrobial agents is explored. The most recent and successful reports of sugar‐based bactericides, bacteriostatic agents, and adhesin binders are covered with focus on the methodologies employed in their synthesis, resulting in a useful compilation of state‐of ...
Ana Marta de Matos
wiley +1 more source
Novel molecules and target genes for vegetative heat tolerance in wheat
Plant-Environment Interactions, Volume 3, Issue 6, Page 264-289, December 2022., 2022 Chronic heat stress induces distinct physiological, metabolomic, and transcriptomic changes in a heat‐tolerant Triticum aestivum cultivar, Cadenza, compared to a susceptible cultivar, Paragon. Previously uncharacterized metabolites and genes are differentially regulated in the heat‐tolerant cultivar, providing potential for future crop heat tolerance ...
Teresa Rose +10 more
wiley +1 more source
Journal of Clinical Laboratory Analysis, Volume 36, Issue 7, July 2022., 2022 Figure 1 Expression of OGG1 in HCC, (A) expression of OGG1 in nucleoplasma, (B, C) OGG1 expression in healthy liver tissues, (D, E, F) OGG1 expression in liver tissues of HCC patients (G) expression of OGG1 in HCC based on sample type (H) nodal metastasis status (I) TP53 mutation status (J) age (K) gender (L) race (M) stage (N) grade (O) histological ...
He Zhang +5 more
wiley +1 more source
Pharmacomicrobiomics: Influence of gut microbiota on drug and xenobiotic metabolism
The FASEB Journal, Volume 36, Issue 6, June 2022., 2022 Abstract Gut microbiota is the most diverse and complex biological ecosystem, which is estimated to consist of greater than 5 million distinct genes and 100 trillion cells which are in constant communication with the host environment. The interaction between the gut microbiota and drugs and other xenobiotic compounds is bidirectional, quite complicated,
Ifeoma Julieth Dikeocha +3 more
wiley +1 more source
Regio‐ and Stereoselective Steroid Hydroxylation at C7 by Cytochrome P450 Monooxygenase Mutants
Angewandte Chemie, Volume 132, Issue 30, Page 12599-12605, July 20, 2020., 2020 One mutant, six targets: The regio‐ and stereoselective C−H activation for hydroxylation of six different steroids with formation of C7β alcohols was accomplished using a single P450 mutant evolved by protein library construction based on a special DNA assembly and cloning procedure.
Aitao Li +11 more
wiley +2 more sources