Results 141 to 150 of about 165,169 (375)
Cell Death and Disease, 2014 Misincorporation of genomic uracil and formation of DNA double strand breaks (DSBs) are known consequences of exposure to TS inhibitors such as pemetrexed.
L. Weeks +3 more
semanticscholar +1 more source
The Enzymatic Conversion of Uracil 5-Carboxylic Acid to Uracil and Carbon Dioxide
Journal of Biological Chemistry, 1970 The enzymatic decarboxylation of uracil 5-carboxylic acid has been demonstrated. A partially purified enzyme preparation has been obtained from Neurospora crassa which stoichiometrically converts uracil 5-carboxylic acid to uracil and carbon dioxide. No cofactor requirement for uracil 5-carboxylic acid decarboxylase activity was detected.
M.T. Abbott +2 more
openaire +3 more sources
Chemistry &Biodiversity, EarlyView.ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves +3 more
wiley +1 more source
Growth Inhibition of a Yeast by Uracil, and its Reversal by Arginine [PDF]
, 1950 E. J. Miller, Joseph S. Harrison
openalex +1 more source
First-principles GW calculations for DNA and RNA nucleobases
, 2011 On the basis of first-principles GW calculations, we study the quasiparticle properties of the guanine, adenine, cytosine, thymine, and uracil DNA and RNA nucleobases.
A. Travers +6 more
core +4 more sources
Journal of Chemical Physics, 2014 Electron attachment to uracil was investigated by applying time-resolved photoelectron imaging to iodide-uracil (I(-)U) complexes. In these studies, an ultraviolet pump pulse initiated charge transfer from the iodide to the uracil, and the resulting ...
S. King +3 more
semanticscholar +1 more source
Clade III Synthases Add Cyclic and Linear Terpenoids to the Psilocybe Metabolome
ChemBioChem, EarlyView.The Psilocybe cubensis terpene synthases, CubB‐CubE, were investigated. Product formation assays identified CubB as a (3R,6E)‐(‐)‐nerolidol or linalool synthase, whereas CubC is a multiproduct synthase catalyzing the formation of β‐caryophyllene and other linear and cyclic sesquiterpenes/‐terpenoids.
Nick Zschoche +7 more
wiley +1 more source
A randomized trial of adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung.
New England Journal of Medicine, 2004 BACKGROUND In a previous phase 3 trial of adjuvant chemotherapy after resection of non-small-cell lung cancer, a combination of uracil and tegafur (often referred to as UFT) taken orally was shown to prolong survival.
H. Kato +10 more
semanticscholar +1 more source
ChemBioChem, EarlyView.A cyclized helix‐loop‐helix (cHLH) peptide is used as a molecular scaffold to generate cell‐permeable protein–protein interactions inhibitors by bifunctional grafting. The steroid receptor coactivator‐1 (SRC1) epitope (red) was grafted onto the C‐terminal helix, and six arginine residues (cyan) were grafted onto the other helix.
Daisuke Fujiwara +8 more
wiley +1 more source
Controlling Topology of a Telomeric G‐quadruplex DNA With a Chemical Cross‐link
Chemistry – A European Journal, EarlyView.Thermodynamically stable G‐quadruplex (G4) DNA: Chemical cross‐linking between distant nucleotides led to formation of G4‐DNA that is stable in the presence of complementary DNA. This methodology can be used to reliably form G4s within DNA fibers for subsequent structural studies of G4‐protein interactions.
Bruce Chilton +4 more
wiley +1 more source