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THE METABOLISM OF URACIL

Canadian Journal of Biochemistry and Physiology, 1957
Oxygen uptake could not be demonstrated when uracil, uridine, or uridylic acid and various supplements were incubated with rat liver preparations. Attention was directed towards the likelihood that the initial step of uracil catabolism in mammals is a reduction such as occurs in yeasts. Various techniques were employed to measure the possible reduction
Bruce McKay   +2 more
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Photodissociation of uracil

Physical Chemistry Chemical Physics, 2007
We investigate the photochemistry and photodissociation dynamics of uracil by two-colour photofragment Doppler spectroscopy and by two-colour slice imaging at excitation wavelengths between 268 and 235 nm. We observe the loss of a hydrogen atom upon excitation into the pipi* state.
Christof Schon   +4 more
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Uracil Photoproducts from Uracil Irradiated in Ice

Science, 1969
Two new products were isolated from uracil irradiated with ultraviolet light in frozen aqueous solution. As judged by mass, nuclear magnetic resonance, and ultraviolet and infrared spectra, one is a photopolymer, U 3 , and the structure of the other is probably 6-4′-[pyrimidin-2′-one]-uracil.
S. Y. Wang, M. N. Khattak
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Oral Tegafur/Uracil

Drugs & Aging, 2001
Tegafur is a prodrug of the antineoplastic agent fluorouracil, and is administered in a 1:4 molar ratio with the fluorouracil modulator uracil. Oral tegafur/uracil 300 mg/m(2)/day plus calcium folinate 75 or 90 mg/day for 28 days every 35 days was as effective as intravenous (IV) fluorouracil 425 mg/m(2)/day plus folinic acid 20 mg/m(2)/day for 5 days ...
Karen L. Goa, Keri Wellington
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The Photochemistry of Uracil: A Reinvestigation

Photochemistry and Photobiology, 2010
AbstractResults from a re‐examination of the photochemical reactions undergone by uracil (Ura) are presented. Irradiation of Ura in frozen aqueous solution at −78.5°C produces two diastereomeric (6‐4) products, namely the cis and trans isomers of 5‐hydroxy‐6‐4′‐(pyrimidin‐2′‐one)‐5,6‐dihydrouracil.
Martin D. Shetlar, Vladimir J. Basus
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Uracil-DNA Glycosylases and DNA Uracil Repair

1989
Publisher Summary This chapter reviews the DNA uracil repair and uracil–DNA glycosylases (UDG). The major source of DNA uracil in prokaryotic and eukaryotic cells is transient incorporation of dUMP during replication. This replicative uracil is quickly repaired by UDG, apyramidinic/apurinic (AP) endonucleases, and other enzymes of excision repair ...
O.N. Aprelikova, N.V. Tomilin
openaire   +3 more sources

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