Results 191 to 200 of about 165,169 (375)

Navigating Past Oceans: Comparing Metabarcoding and Metagenomics of Marine Ancient Sediment Environmental DNA

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT The condition of ancient marine ecosystems provides context for contemporary biodiversity changes in human‐impacted oceans. Sequencing sedimentary ancient DNA (sedaDNA) is an emerging method for generating high‐resolution biodiversity time‐series data, offering insights into past ecosystems.
Luke E. Holman   +8 more
wiley   +1 more source

Coordinate Control of Ribonucleic Acid Synthesis during Uracil Deprivation

open access: hybrid, 1969
Robert A. Lazzarini   +2 more
openalex   +1 more source

Designing Epigenetic Clocks for Wildlife Research

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT The applications of epigenetic clocks – statistical models that predict an individual's age based on DNA methylation patterns – are expanding in wildlife conservation and management. This growing interest highlights the need for field‐specific design best practices.
Levi Newediuk   +5 more
wiley   +1 more source

Feasibility and population exposure of 5-fluorouracil using therapeutic drug monitoring (PREDICT-5FU): A multicentre clinical trial. [PDF]

open access: yesBr J Clin Pharmacol
Aim PREDICT‐5FU aimed to document 5‐fluorouracil (5FU) exposure in a cancer population and to evaluate the feasibility of 5FU and capecitabine therapeutic drug monitoring (TDM) in patients receiving standard doses and schedules. Methods Multicentre, prospective, observational single‐arm study.
Glewis S   +12 more
europepmc   +2 more sources

Independent Avian Epigenetic Clocks for Ageing and Development

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT Information on individual age is a fundamental aspect in many ecological and evolutionary studies. However, accurate and non‐lethal methods that can be applied to estimate the age of wild animals are often absent. Furthermore, since the process of ageing is accompanied by a physical decline and the deterioration of biological functions, the ...
Ayke Haller   +3 more
wiley   +1 more source

Uracil Metabolism in Tadpoles during Thyroxine-induced Metamorphosis

open access: hybrid, 1964
N Akamatsu   +2 more
openalex   +1 more source

BRCA1 Promoter Methylation in Ovarian Cancer: Clinical Relevance and a Novel Diagnostic Approach Using Fragment Analysis

open access: yesCancer Science, EarlyView.
With the aim of clinical applications, we established a simplified evaluation method for BRCA1 methylation using fragment analysis, called BRCA1‐FAM. We confirmed that high‐grade serous ovarian cancer patients with BRCA1 methylation had poor prognosis.
Saki Tsuchimochi   +20 more
wiley   +1 more source

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