Results 201 to 210 of about 165,169 (375)

Hypoxia Inhibitor Improves Iodine Uptake Disorder in Thyroid Cancer Through the hsa_circ_0023990/miR‐448/DNMT1/NIS Axis

Cancer Science, EarlyView.
Our study reveals that hypoxia inhibitors ameliorate iodine uptake dysfunction in thyroid cancer by acting on the hsa_circ_0023990/miR‐448/DNMT1/NIS signaling pathway. ABSTRACT This research seeks to investigate how hypoxia inhibitors enhance iodine uptake in thyroid cancer cells. Clinical samples were gathered and assessed for hsa_circ_0023990, DNMT1,
Ruiqin Gou, Shiqi Chen, Yangyang Lei, Pengqing Wu, Xuezhong Chen, Qing Zhang   +5 more
wiley   +1 more source

Syntheses of 1-(5'-Amino-5'-deoxy-β-D-xylofuranosyl) uracil and Its N<SUB>3</SUB>-Methyl Derivative

, 1969
Kiyomi Kikugawa, Motonobu Ichino, Tsuneo Kusama, Tyunoshin Ukita   +3 more
openalex   +2 more sources

Stress‐inducible phosphoprotein 1 (Sti1/Stip1/Hop) sequesters misfolded proteins during stress

The FEBS Journal, EarlyView.
Stress‐inducible phosphoprotein 1 (Sti1/Stip1/Hop) is a major co‐chaperone to both Hsp90 and Hsp70. We find that misbalanced expression of Sti1 in yeast and mammalian cells causes severe growth defects. Deletion of STI1 causes an accumulation of soluble misfolded ubiquitinated proteins and a strong activation of the heat shock response.
Benjamin S. Rutledge, Young J. Kim, Donovan W. McDonald, Juan C. Jurado‐Coronel, Marco A. M. Prado, Jill L. Johnson, Wing‐Yiu Choy, Martin L. Duennwald   +7 more
wiley   +1 more source

Splitting of Uracil Dimer by High-energy Electrons

, 1963
B Schmidt, D Hartmann, K Grossgebauer, W Schumacher   +3 more
openalex   +1 more source

A steric gate prevents mutagenic dATP incorporation opposite 8‐oxo‐deoxyguanosine in mitochondrial DNA polymerases

The FEBS Journal, EarlyView.
Reactive oxygen species induce mutagenic DNA lesions, such as 8‐oxo‐2′‐deoxyguanosine (8‐oxodG), which acts as a template for dCMP and dAMP incorporation through its anti and syn conformations. Specific residues must regulate the fidelity of templated 8‐oxodG.
Noe Baruch‐Torres, Carlos H. Trasviña‐Arenas, Alexandru Ionut Gilea, Upeksha C. Dissanayake, Missael Molina‐Jiménez, Paola L. García‐Medel, Corina Díaz‐Quezada, Tiziana Lodi, G. Andrés Cisneros, Enrico Baruffini, Luis G. Brieba   +10 more
wiley   +1 more source

Mismatch uracil DNA glycosylase (Mug) is maintained in the Corynebacterium pseudotuberculosis genome and exhibits affinity for uracil but not other types of damage. [PDF]

Genet Mol Biol
Resende BC, Cassiano CSS, Rios DL, Ladeira TQ, Azevedo VAC, Santos LLD, Valenzuela-Pérez L, Cabrera G, Machado CR, Lopes DO.   +9 more
europepmc   +1 more source

Aminosäure-Abhängigkeit des ¹⁴C-Uracil-Einbaus in Phagen-RNA in Zellen mit „Stringent“ RNA-Synthesekontrolle [PDF]

, 1967
Peter Knolle
openalex   +1 more source

Saccharomyces cerevisiae Mub1, a substrate adaptor of E3 ubiquitin ligase Ubr2, modulates sensitivity to cell wall stressors through multiple transcription factors

The FEBS Journal, EarlyView.
We show that Mub1 links cell wall robustness with the ubiquitin‐proteasome system. As an adaptor protein of the E3 ubiquitin ligase Ubr2, it facilitates the ubiquitination of various transcription factors, including Mcm1 and Swi4. Yeasts evolved a complex regulatory programme to build and maintain their cell wall, the primary structure through which ...
Nada Šupljika, Antonia Paić, Ana Novačić, Tea Martinić Cezar, Béatrice Vallée, Renata Teparić, Igor Stuparević, Bojan Žunar   +7 more
wiley   +1 more source

Ion-DNA Interactions as a Key Determinant of Uracil DNA Glycosylase Activity. [PDF]

Biochemistry
Greenwood SN, Dispensa AN, Wang M, Bauer JR, Vaden TD, Liu Z, Weiser BP.   +6 more
europepmc   +1 more source

Thyroid lesions of neuroendocrine origin? Thinking of a “polka‐dotted” zebra! Case series from three Italian referral centers and review of the literature

Journal of Neuroendocrinology, EarlyView.
Thyroid metastases from neuroendocrine neoplasm (NEN) should be considered in case of suspicious thyroid nodules in patients with a positive medical history of NEN, mainly of thoracic origin, even after many years from the initial diagnosis. The differential diagnosis from primary intrathyroidal NEN is challenging.
Tiziana Feola, Alessia Cozzolino, Federica Grillo, Maria Francesca Birtolo, Irene Aini, Erika Messina, Roberto Minotta, Alessia Filice, Isabella Zanata, Paola Razzore, Manila Rubino, Andrea M. Isidori, Annamaria Colao, Antongiulio Faggiano, Elisa Giannetta, on behalf of NIKE group, Irene Aini, Manuela Albertelli, Ylenia Alessi, Simone Antonini, Luigi Barrea, Elio Benevento, Maria Francesca Birtolo, Federica Campolo, Celeste Cantone, Silvia Carra, Rob‐erta Centello, Alessia Cozzolino, Federica De Cicco, Valentina Di Vito, Beatrice Fazzalari, Stefano Gay, Elisa Giannetta, Federica Grillo, Elia Guadagno, Valentina Guarnotta, Iderina Hasballa, Alice Laffi, Andrea Lania, Alessia Liccardi, Rossella Mazzilli, Erika Messina, Roberto Minotta, Giovanna Muscogiuri, Carla Pandozzi, Gabriella Pugliese, Giulia Puliani, Alberto Ragni, Manila Rubino, Rosaria Maddalena Ruggeri, Franz Sesti, Maria Grazia Tarsitano, Ludovica Verde, Giovanni Vitale, Virginia Zamponi, Isabella Zanata, Roberta Modica, Giuseppe Fanciulli, Anna La Salvia, Erika Maria Grossrubatscher, Francesco Ferrau, Alessandro Veresani, Flaminia Russo   +62 more
wiley   +1 more source