Results 31 to 40 of about 149,629 (313)

Excited States of Proton-bound DNA/RNA Base Homo-dimers: Pyrimidines [PDF]

open access: yes, 2014
We are presenting the electronic photo fragment spectra of the protonated pyrimidine DNA bases homo-dimers. Only the thymine dimer exhibits a well structured vibrational progression, while protonated monomer shows broad vibrational bands. This shows that
Adesokan A. a   +55 more
core   +5 more sources

Effects of the pyrE deletion mutant from Bacillus thuringiensis on gut microbiota and immune response of Spodoptera exigua

open access: yesFrontiers in Microbiology, 2023
The gut microbiota is essential for the growth and development of insects, and the intestinal immune system plays a critical role in regulating the homeostasis of intestinal microorganisms and their interactions with pathogenic bacteria.
Dan Zhao   +8 more
doaj   +1 more source

Uracil-Induced Down-Regulation of the Yeast Uracil Permease [PDF]

open access: yesJournal of Bacteriology, 1999
ABSTRACT In Saccharomyces cerevisiae the FUR4 -encoded uracil permease catalyzes the first step of the pyrimidine salvage pathway. The availability of uracil has a negative regulatory effect upon its own transport.
K, Séron   +3 more
openaire   +2 more sources

Monotriazoles Derived from Uracil and Thymine as Corrosion Inhibitor for API 5L X52 Steel in 1 M H2SO4

open access: yesInternational Journal of Electrochemical Science, 2018
In this study, the corrosion inhibition of monotriazoles derived from uracil and thymine was studied with electrochemical impedance spectroscopy (EIS) on API 5L X52 steel in 1 M H2SO4.
A. Espinoza-Vázquez   +4 more
doaj   +1 more source

Uracil restores susceptibility of methicillin-resistant Staphylococcus aureus to aminoglycosides through metabolic reprogramming

open access: yesFrontiers in Pharmacology, 2023
Background: Methicillin-resistant Staphylococcus aureus (MRSA) has now become a major nosocomial pathogen bacteria and resistant to many antibiotics. Therefore, Development of novel approaches to combat the disease is especially important.
Lvyuan Fan   +8 more
doaj   +1 more source

Architecturally diverse proteins converge on an analogous mechanism to inactivate Uracil-DNA glycosylase [PDF]

open access: yes, 2013
Uracil-DNA glycosylase (UDG) compromises the replication strategies of diverse viruses from unrelated lineages. Virally encoded proteins therefore exist to limit, inhibit or target UDG activity for proteolysis.
A. R. Cole   +39 more
core   +1 more source

Synthesis, Herbicidal Activity, Mode of Action, and In Silico Analysis of Novel Pyrido[2,3-d]pyrimidine Compounds

open access: yesMolecules, 2023
Natural products are a main source of new chemical entities for use in drug and pesticide discovery. In order to discover lead compounds with high herbicidal activity, a series of new pyrido[2,3-d] pyrimidine derivatives were designed and synthesized ...
Lijing Min   +10 more
doaj   +1 more source

Structure of isolated biomolecules by electron diffraction-laser desorption: uracil and guanine [PDF]

open access: yes, 2009
We report the structure of isolated biomolecules, uracil and guanine, demonstrating the capability of a newly developed electron diffraction apparatus augmented with surface-assisted IR laser desorption.
Gahlmann, Andreas   +2 more
core   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

The role of Duschinsky rotation in intersystem crossing: A case study of uracil [PDF]

open access: yesJournal of the Serbian Chemical Society, 2011
The intersystem crossing rate for the transition between the lowest excited singlet and triplet electronic states of uracil was studied by means of ab initio methods.
Etinski Mihajlo
doaj   +1 more source

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