Results 41 to 50 of about 149,629 (313)
Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy [PDF]
, 2013 Uracil in DNA is an important cause of mutagenesis. SMUG1 is a uracil DNA glycosylase that removes uracil through base excision repair. SMUG1 also processes radiation induced oxidative base damage as well as 5-fluorouracil incorporated into DNA during
Abdel-Fatah, TMA +9 more
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Біологічні студії, 2015 For the first time, on the quantum-mechanical level of theory MP2/6-311++G(2df,pd)//B3LYP/6-311++G(d,p), a full set of hydrogen (H)-bonded hetero associates m9Ade·m1Ura in the main tautomeric forms consisting of 18 different structures was obtained ...
D. Plodnik, I. Voiteshenko, D. Hovorun
doaj +1 more source
Ultraviolet relaxation dynamics in uracil: Time-resolved photoion yield studies using a laser-based thermal desorption source [PDF]
, 2018 Wavelength-dependent measurements of the RNA base uracil, undertaken with nanosecond ultraviolet laser pulses, have previously identified a fragment at m/z = 84 (corresponding to the C3H4N2O+ ion) at excitation wavelengths ≤232 nm.
Bockova, Jana +9 more
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A stoichiometric reaction scheme for Saccharothrix algeriensis growth and thiolutin production [PDF]
, 2010 A new bacterial species, Saccharothrix algeriensis NRRL B-24137, was isolated in 1992 in the Sahara desert. This filamentous bacterium is able to produce dithiolopyrrolones, molecules presenting antibacterial, antifungal, and anticancer properties.
Brandam, Cédric +3 more
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Scientific Reports, 2017 Both a DNA lesion and an intermediate for antibody maturation, uracil is primarily processed by base excision repair (BER), either initiated by uracil-DNA glycosylase (UNG) or by single-strand selective monofunctional uracil DNA glycosylase (SMUG1).
Lene Alsøe +15 more
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Pyrimidine Biosynthesis and Ribonucleoside Metabolism in Species of Pseudomonas
Fermentation, 2023 Pyrimidine biosynthesis and ribonucleoside metabolism in species of Pseudomonas was the focus of this review, in relation to their current taxonomic assignments in different homology groups.
Thomas P. West
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Rewriting Human History and Empowering Indigenous Communities with Genome Editing Tools. [PDF]
, 2020 Appropriate empirical-based evidence and detailed theoretical considerations should be used for evolutionary explanations of phenotypic variation observed in the field of human population genetics (especially Indigenous populations). Investigators within
Fox, Keolu +2 more
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Acta Chimica Slovenica, 2018 The photocyclodimerization mechanisms of two oxo tautomers of uracil and 6-azauracil were studied at the CC2 level of theory and cc-pVDZ basis functions.
Pavlina Bogomilova Kancheva +1 more
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Synthesis of 5-substituted 2'-deoxyuridine-5'-phosphonate analogues and evaluation of their antiviral activity [PDF]
, 2012 A small series of 5-(hetero)aryl-modified nucleoside phosphonates was synthesized via an 8-step procedure including a Wittig reaction and Suzuki-Miyaura coupling.
Balzarini, Jan +4 more
core +1 more source
Biochemistry and Biophysics Reports, 2021 Uracil DNA glycosylases are an important class of enzymes that hydrolyze the N-glycosidic bond between the uracil base and the deoxyribose sugar to initiate uracil excision repair.
Avani Mehta +4 more
doaj +1 more source