Results 1 to 10 of about 5,275 (178)

Spinal gout recovery with urate‐lowering therapy: A case report [PDF]

Clinical Case Reports
Key Clinical Message The occurrence of spinal gout resulting in erosion of the superior articular process in patients with low back pain is uncommon, potentially leading to misdiagnosis and inappropriate treatment.
Kunfang Huo, Jialin Zhang, Yanhua Lin, Qianyun Chen, Han Zhong, Bin Yang   +5 more
doaj   +4 more sources

Gout Remission as a Goal of Urate-Lowering Therapy: A Critical Review [PDF]

Pharmaceuticals, 2023
Urate-lowering therapies for the management of gout lead to a reduction in serum urate levels, monosodium urate crystal deposition, and the clinical features of gout, including painful and disabling gout flares, chronic gouty arthritis, and tophi.
Adwoa Dansoa Tabi-Amponsah, Sarah Stewart, Graham Hosie, Lisa K. Stamp, William J. Taylor, Nicola Dalbeth   +5 more
doaj   +2 more sources

Urate-lowering therapy and kidney function

Современная ревматология, 2023
Chronic hyperuricemia (CH) and gout are independent risk factors for decreased kidney function. In the last decade, evidence was accumulating that urate-lowering therapy may be an effective method of slowing down the progression of CH and gout-mediated ...
M. S. Eliseev
doaj   +2 more sources

Urate-lowering therapy for heart failure

Современная ревматология, 2019
Heart failure (HF) is one of the major public health problems in developed countries. Hyperuricemia (HU) is often found in patients with chronic HF (CHF) and is a well-known independent predictor for mortality and re-hospitalization for the progression ...
O. V. Zhelyabina, M. S. Eliseev
doaj   +3 more sources

Design and implementation of a Pacific intervention to increase uptake of urate-lowering therapy for gout: a study protocol [PDF]

International Journal for Equity in Health, 2021
Background Gout is a painful chronic disease which disrupts work and family life and can lead to chronic joint damage. Pacific people in Aotearoa/New Zealand experience significant inequities, with over three times the gout prevalence of the non-Pacific ...
Malakai Ofanoa, Samuela Malakai Ofanoa, Maryann Heather, Siobhan Tu’akoi, Hinamaha Lutui, Nicola Dalbeth, Corina Grey, Bert van der Werf, Felicity Goodyear-Smith   +8 more
doaj   +2 more sources

Variation in serum urate levels in the absence of gout and urate lowering therapy [PDF]

BMC Rheumatology, 2021
Background Previous studies have noted significant variation in serum urate (sUA) levels, and it is unknown how this influences the accuracy of hyperuricemia classification based on single data points.
Andrew Shaffer, Elizabeth Rahn, Kenneth Saag, Amy Mudano, Angelo Gaffo   +4 more
doaj   +2 more sources

Urate lowering therapy in patients starting hemodialysis limit gout flares occurrence: ten years retrospective study [PDF]

BMC Nephrology
Background Uncontrolled gout can cause articular impairment but is also associated with a global and cardiovascular excess mortality, especially in dialysis population.
Alexia Steelandt, Ambre Hittinger, Lukshe Kanagaratnam, Isabelle Kazes, Pierre Clavel, Loïs Bolko, Philippe Rieu, Jean-Hugues Salmon   +7 more
doaj   +2 more sources

OAT10/SLC22A13 Acts as a Renal Urate Re-Absorber: Clinico-Genetic and Functional Analyses With Pharmacological Impacts

Frontiers in Pharmacology, 2022
Dysfunctional missense variant of organic anion transporter 10 (OAT10/SLC22A13), rs117371763 (c.1129C>T; p.R377C), is associated with a lower susceptibility to gout.
Yu Toyoda, Yu Toyoda, Yusuke Kawamura, Akiyoshi Nakayama, Keito Morimoto, Seiko Shimizu, Yuki Tanahashi, Takashi Tamura, Takaaki Kondo, Yasufumi Kato, Kimiyoshi Ichida, Hiroshi Suzuki, Nariyoshi Shinomiya, Yasushi Kobayashi, Tappei Takada, Hirotaka Matsuo   +15 more
doaj   +1 more source

The many faces of gout: modern treatment concepts

Клинический разбор в общей медицине, 2021
Gout is a systemic disease caused by the deposition of monosodium urate crystals in various tissues and organs with the subsequent development of autoinflammation.
Irina N. Bobkova, Elena S. Kamyshova
doaj   +1 more source

Urate-lowering drugs in the treatment of gout: The unknown about the known

Научно-практическая ревматология, 2021
The main direction of drug therapy for gout and other diseases associated with hyperuricemia is the long-term use of drugs aimed at correcting the level of uric acid.
T. S. Panevin, M. S. Eliseev, E. L. Nasonov   +2 more
doaj   +1 more source