Results 91 to 100 of about 2,566,443 (193)

Effectiveness of Telehealth Low‐Carbohydrate Intervention in Preventing Chronic Kidney Disease: A Real‐World, Retrospective, Matched Cohort Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9054-9068, October 2026.
ABSTRACT Background Lifestyle interventions targeting metabolic health may influence chronic kidney disease (CKD) risk, particularly among adults with type 2 diabetes and obesity. We evaluated real‐world associations between a telehealth‐delivered, individualized nutrition therapy program (VINT) and CKD incidence and progression compared with usual ...
Shaminie J. Athinarayanan, Petter Bjornstad, Priya V. Shanmugam, Thomas Weimbs, Adam J. Wolfberg, Jeff S. Volek, Jonathan Himmelfarb, Richard J. Johnson   +7 more
wiley   +1 more source

The genetics of gout: towards personalised medicine?

BMC Medicine, 2017
Over the last decade, there have been major advances in the understanding of the genetic basis of hyperuricaemia and gout as well as of the pharmacogenetics of urate-lowering therapy.
Nicola Dalbeth, Lisa K. Stamp, Tony R. Merriman   +2 more
doaj   +1 more source

Kiesselbach’s area nasal septal gouty tophus with an integrated “3 + 2” diagnostic algorithm: a case report

Journal of Medical Case Reports
Background Gout, characterized by monosodium urate crystal deposition, rarely involves the nasal septum, with only a few reported cases. Such unusual presentations can mimic other conditions, necessitating prompt and accurate diagnosis.
Weikun Chen, Wanling Chen, Duanyue Guo, Ziyue Wang, Ziwen Shi, Junwei Zhong   +5 more
doaj   +1 more source

Battle of the strategies: diet versus drug therapy for gout

Современная ревматология
The best results in combating gout are achieved through a combination of diet and drug therapy. Urate-lowering therapy, which includes febuxostat, has been shown to be more effective and convenient than diet when it comes to achieving and maintaining ...
O. V. Zhelyabina, M. S. Eliseev, A. M. Lila   +2 more
doaj   +1 more source

Uricases: reflections on recent developments in the management of challenging gout patients [PDF]

Exploration of Musculoskeletal Diseases
Oral urate-lowering therapy (ULT) is key to treating gout. However, many patients receiving oral ULT do not achieve the target serum urate (SU) levels, partly because some patients cannot tolerate or have contraindications to their use, mainly due to ...
Naomi Schlesinger, Dan Kaufmann
doaj   +1 more source

Schematic of the samples selection process for association between urate-lowering therapy and risk of type 2 diabetes mellitus.

, 2019
Schematic of the samples selection process for association between urate-lowering therapy and risk of type 2 diabetes mellitus.
Hsin-Wen Chang (216673), Ya-Wen Lin (2738968), Ming-Hung Lin (4373560), Ruey-Yun Wang (384835), Yu-Ching Lan (431716)   +4 more
core   +1 more source

A prospective clinical study on the efficacy and safety of specific uric acid adsorption hemoperfusion in removing serum uric acid from patients with refractory gout

Zhongguo shuxue zazhi
[Objective] To evaluate the efficacy and safety of the single-use hemoperfusion device (UA230) in treating refractory gout (RG) via plasma perfusion. [Methods] Thirty-four RG patients aged 18-65 years were recruited and randomly divided into a control ...
LI Ying, YANG Yuanming, JING Zhongcui, LIU Jiao, JIANG Dandan, YU Shanshan, WANG Haiyan   +6 more
doaj   +1 more source

Guideline development for the management of gout: role of combination therapy with a focus on lesinurad

Drug Design, Development and Therapy, 2017
Graeme Jones,1 Elena Panova,1 Richard Day2 1Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia; 2University of New South Wales, Medicine, St Vincent’s Hospital, Sydney, NSW, Australia Abstract: The aim of this ...
Jones G, Panova E, Day R
doaj  

Treatment of Gout in Patients with CrCl ≤30 mL/min and/or on Hemodialysis: A Review

Rheumato
Gout is highly prevalent in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD), owing to impaired uric acid excretion. However, treating gout in this population is challenging due to concerns about medication safety and ...
Fares Saliba, Omar Mourad, Jonathan Mina, Fadi Haddadin, Laurence Aoun, Shaza Almardini, Saif Abu-baker, Koushik Sangaraju, Gaetano Di Pietro, Daniel Gaballa, Suzanne El-sayegh   +10 more
doaj   +1 more source

Reconsidering Urate-Lowering Therapy in Chronic Kidney Disease- Guideline Driven Perspectives on the Management of Asymptomatic Hyperuricaemia

Journal of the Pakistan Medical Association
Hyperuricaemia is highly prevalent in patients with chronic kidney disease (CKD), primarily due to reduced renal urate excretion. Elevated serum uric acid (SUA) levels have been linked with CKD progression, cardiovascular disease, and mortality. However,
Sourabh Sharma, Sabine Karam, Intissar Haddiya, Sanjay Kalra   +3 more
doaj   +1 more source