Results 71 to 80 of about 5,544 (172)
Drug Design, Development and Therapy, 2017 Graeme Jones,1 Elena Panova,1 Richard Day2 1Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia; 2University of New South Wales, Medicine, St Vincent’s Hospital, Sydney, NSW, Australia Abstract: The aim of this ...
Jones G, Panova E, Day R
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Treatment of Gout in Patients with CrCl ≤30 mL/min and/or on Hemodialysis: A Review
RheumatoGout is highly prevalent in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD), owing to impaired uric acid excretion. However, treating gout in this population is challenging due to concerns about medication safety and ...
Fares Saliba +10 more
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Journal of the Pakistan Medical AssociationHyperuricaemia is highly prevalent in patients with chronic kidney disease (CKD), primarily due to reduced renal urate excretion. Elevated serum uric acid (SUA) levels have been linked with CKD progression, cardiovascular disease, and mortality. However,
Sourabh Sharma +3 more
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Impact of pegloticase on patient outcomes in refractory gout: current perspectives
Open Access Rheumatology: Research and Reviews, 2018 Rita N Cunha,1 Renata Aguiar,1 Filipa Farinha2 1Rheumatology Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal; 2Centre for Rheumatology, University College London, London, UK Abstract: Gout is currently the most frequent cause of ...
Cunha RN, Aguiar R, Farinha F
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Clinical Case ReportsA 58‐year‐old male with a history of gout presented with new‐onset neck pain. Dual‐energy CT revealed extensive urate crystal deposition in his cervical part and sternoclavicular joints, an uncommon manifestation.
Chenyang Zhang +3 more
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Moving urate-lowering therapy in gout beyond guideline recommendations
Seminars in Arthritis and RheumatismThe 'treat-to target serum urate strategy' when using urate-lowering therapy has been recommended by most specialist rheumatology societies for many years. An alternative "treat-to-avoid-symptoms" in gout has been suggested, albeit without a clear definition of what this means and how it might be implemented in clinical trials or clinical practice ...
Lisa K Stamp, Nicola Dalbeth
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Cardiology JournalXanthine oxidase inhibitors, including allopurinol and febuxostat, are the first-line treatment of hyperuricemia. This meta-analysis investigated the association between urate-lowering therapy and all-cause mortality in different chronic diseases to ...
Marcin M. Nowak +3 more
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Utility of the Morisky Medication Adherence Scale in gout: a prospective study
Patient Preference and Adherence, 2016 CSL Tan,1 GG Teng,1,2 KJ Chong,2 PP Cheung,1,2 AYN Lim,1,2 HL Wee,3,4 A Santosa1,2 1University Medicine Cluster, Division of Rheumatology, National University Health System, 2Department of Medicine, Yong Loo Lin School of Medicine, 3Department of ...
Tan CSL +6 more
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Arthritis Research & TherapyBackground People with gout and combined-type hyperuricemia, defined as renal urate overload and renal urate under-excretion, have diminished responsiveness to urate-lowering therapy.
Kai Guo +17 more
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The experiences and perspectives of people with gout on urate self‐monitoring
Health ExpectationsIntroduction Gout management remains suboptimal despite safe and effective urate‐lowering therapy. Self‐monitoring of urate may improve gout management, however, the acceptability of urate self‐monitoring by people with gout is unknown.
Toni J. F. Michael +8 more
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