Urate-lowering therapy - Open Access .click

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Influence of urate-lowering therapies on renal handling of uric acid

Clinical Rheumatology, 2014
The purpose of this study is to investigate the effect of urate-lowering therapies (ULTs) on renal uric acid excretion in gout patients. This prospective observational study involved 106 primary gout patients and 51 healthy controls. Gout patients received ULT with either xanthine oxidase inhibitors or the uricosuric agent benzbromarone.
Lili, Ma +6 more
openaire +2 more sources

Ultrasound in gout: A useful tool for following urate-lowering therapy

Joint Bone Spine, 2015
We aimed to determine the ability of ultrasonography (US) to show decrease or disappearance of urate deposits in gouty patients requiring urate-lowering therapy (ULT).To be included in this prospective single-centre study, patients needed toexhibit (1) proven gout by monosodic urate (MSU) crystals in synovial fluid and (2) US-evidenced urate deposits ...
Sébastien, Ottaviani +5 more
openaire +2 more sources

Pharmacist-managed titration of urate-lowering therapy to streamline gout management

Rheumatology International, 2019
The treat-to-target approach for serum uric acid is the recommended model in gout management according to the 2012 American College of Rheumatology (ACR) guidelines. Adherence to urate-lowering therapy (ULT) can be difficult for patients due to barriers, which include medication burden, financial hardship, and lack of medical literacy.
Irvin J. Huang +5 more
openaire +2 more sources

Gradual reduction of tophaceous deposits during urate-lowering therapy