Results 81 to 90 of about 2,554,026 (187)

Current issues in the practical use of allopurinol in patients with gout and hyperuricemia

open access: yesСовременная ревматология
The cornerstone of the treatment of gout and hyperuricemia (HU) is the use of urate-lowering drugs, primarily xanthine oxidase inhibitors. Allopurinol, which has been used to treat gout for six decades, is the first line urate-lowering therapy (ULT ...
M. S. Eliseev
doaj   +1 more source

Stretchable and Strain‐Tolerant Gold‐Coated Fibrous Biosensor for Superoxide Anion Monitoring

open access: yesAdvanced Materials Technologies, Volume 11, Issue 16, 21 August 2026.
A breathable, stretchable gold nanomesh–TPU fiber platform is developed via controlled electroless deposition, enabling uniform through‐thickness conductivity while preserving porosity. Functionalized with superoxide dismutase, the system achieves selective, real‐time electrochemical detection of superoxide with high sensitivity, mechanical durability,
Jafar M. Batayneh, Ahyeon Koh
wiley   +1 more source

The genetics of gout: towards personalised medicine?

open access: yesBMC Medicine, 2017
Over the last decade, there have been major advances in the understanding of the genetic basis of hyperuricaemia and gout as well as of the pharmacogenetics of urate-lowering therapy.
Nicola Dalbeth   +2 more
doaj   +1 more source

Kiesselbach’s area nasal septal gouty tophus with an integrated “3 + 2” diagnostic algorithm: a case report

open access: yesJournal of Medical Case Reports
Background Gout, characterized by monosodium urate crystal deposition, rarely involves the nasal septum, with only a few reported cases. Such unusual presentations can mimic other conditions, necessitating prompt and accurate diagnosis.
Weikun Chen   +5 more
doaj   +1 more source

Battle of the strategies: diet versus drug therapy for gout

open access: yesСовременная ревматология
The best results in combating gout are achieved through a combination of diet and drug therapy. Urate-lowering therapy, which includes febuxostat, has been shown to be more effective and convenient than diet when it comes to achieving and maintaining ...
O. V. Zhelyabina   +2 more
doaj   +1 more source

Uricases: reflections on recent developments in the management of challenging gout patients [PDF]

open access: yesExploration of Musculoskeletal Diseases
Oral urate-lowering therapy (ULT) is key to treating gout. However, many patients receiving oral ULT do not achieve the target serum urate (SU) levels, partly because some patients cannot tolerate or have contraindications to their use, mainly due to ...
Naomi Schlesinger, Dan Kaufmann
doaj   +1 more source

Schematic of the samples selection process for association between urate-lowering therapy and risk of type 2 diabetes mellitus.

open access: yes, 2019
Schematic of the samples selection process for association between urate-lowering therapy and risk of type 2 diabetes mellitus.
Hsin-Wen Chang (216673)   +4 more
core   +1 more source

A prospective clinical study on the efficacy and safety of specific uric acid adsorption hemoperfusion in removing serum uric acid from patients with refractory gout

open access: yesZhongguo shuxue zazhi
[Objective] To evaluate the efficacy and safety of the single-use hemoperfusion device (UA230) in treating refractory gout (RG) via plasma perfusion. [Methods] Thirty-four RG patients aged 18-65 years were recruited and randomly divided into a control ...
LI Ying   +6 more
doaj   +1 more source

Guideline development for the management of gout: role of combination therapy with a focus on lesinurad

open access: yesDrug Design, Development and Therapy, 2017
Graeme Jones,1 Elena Panova,1 Richard Day2 1Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia; 2University of New South Wales, Medicine, St Vincent’s Hospital, Sydney, NSW, Australia Abstract: The aim of this ...
Jones G, Panova E, Day R
doaj  

Venous thromboembolism in patients with gout and the impact of hospital admission, disease duration and urate-lowering therapy.

open access: yes, 2019
BACKGROUND: Systemic inflammatory diseases have been associated with increased risk of venous thromboembolism. We aimed to quantify the risk of venous thromboembolism in patients with gout, the most common inflammatory arthritis, and to assess how ...
Roddy, E   +3 more
core   +2 more sources

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