Results 81 to 90 of about 2,566,374 (138)

Is Urate-lowering therapy a prevention of first gout episode? [PDF]

The growing problem of gout is beginning to raise questions about how we can effectively prevent this disease. This work examines the effect of urate-lowering therapy on preventing the onset of a first episode of gout—an effect that is not entirely clear,
Kulasza, Paulina Sara, Francuziak, Anna Ewelina, Szeliga, Aleksandra, Książek, Tomasz Karol, Dembicki, Piotr Mikołaj, Kalinowska, Weronika, Szczepański, Michał, Dzieszko, Natalia, Borowski, Maciej, Kozłowska, Kinga   +9 more
core  

Gout : its epidemiology and therapeutic effect of urate-lowering agent

, 2020
Gout is chronic inflammatory arthritis characterised by monosodium urate crystal deposition in peripheral joints. The global prevalence of gout is increasing except Taiwan and the United States.
Tsoi, Man-fung, 蔡文峰
core  

Utility of the Morisky Medication Adherence Scale in gout: a prospective study

Patient Preference and Adherence, 2016
CSL Tan,1 GG Teng,1,2 KJ Chong,2 PP Cheung,1,2 AYN Lim,1,2 HL Wee,3,4 A Santosa1,2 1University Medicine Cluster, Division of Rheumatology, National University Health System, 2Department of Medicine, Yong Loo Lin School of Medicine, 3Department of ...
Tan CSL, Teng GG, Chong KJ, Cheung PP, Lim AYN, Wee HL, Santosa A   +6 more
doaj  

Effects of adding urinary alkalizer citrate mixture to febuxostat in gout patients with combined-type hyperuricemia and low urine pH: a prospective cohort study

Arthritis Research & Therapy
Background People with gout and combined-type hyperuricemia, defined as renal urate overload and renal urate under-excretion, have diminished responsiveness to urate-lowering therapy.
Kai Guo, Changgui Li, Robert Terkeltaub, Nicola Dalbeth, Xuefeng Wang, Xiaopeng Ji, Ying Chen, Lingling Cui, Zhen Liu, Xinde Li, Yuwei He, Jie Lu, Wenyan Sun, Lin Han, Hui Zhang, Aichang Ji, Mingshu Sun, Can Wang   +17 more
doaj   +1 more source

The experiences and perspectives of people with gout on urate self‐monitoring

Health Expectations
Introduction Gout management remains suboptimal despite safe and effective urate‐lowering therapy. Self‐monitoring of urate may improve gout management, however, the acceptability of urate self‐monitoring by people with gout is unknown.
Toni J. F. Michael, Jian S. Chan, Stephen Hughes, Daniel F. B. Wright, Matthew J. Coleshill, Dyfrig A. Hughes, Richard O. Day, Parisa Aslani, Sophie L. Stocker   +8 more
doaj   +1 more source

The Uric Acid Dilemma: A Nutritional Odyssey

Annals of Rheumatology and Autoimmunity
Gout prevalence continues to rise worldwide, with an estimated 53.9 million cases in 2019, representing a 22% increase in age-standardized prevalence compared to 1990. Although urate-lowering pharmacotherapy remains the cornerstone of management, dietary
Muhammed Jasim Abdul Jalal
doaj   +1 more source

Can Urate Lowering Therapy Be Stopped in Gout? Rationale and Design of Two Large Randomised Trials

Lifelong urate-lowering therapy (ULT) is recommended for gout to prevent flares and urate deposition. However, concerns about its adherence, long-term side effects, and the necessity of continuous treatment after achieving remission raise critical ...
Pascal Richette, Noortje van Herwaarden, Leo A. B. Joosten, Marcel Flendrie   +3 more
core   +1 more source

Factors for achieving target serum uric acid levels after initiating urate-lowering therapy in patients with gout: results from the ULTRA registry. [PDF]

Sci Rep, 2023
Do H, Choi HJ, Choi B, Son CN, Kim SH, Choi SR, Kim JH, Kim MJ, Shin K, Kim HO, Song R, Lee SW, Ahn JK, Lee SG, Lee CH, Son KM, Moon KW.   +16 more
europepmc   +1 more source

Early urate-lowering therapy and cardiometabolic risk in adults without documented major cardiometabolic disease: a real-world cohort study. [PDF]

Front Endocrinol (Lausanne)
Huo AP, Wang SI, Leong PY, Wei JC, Hsu TC.   +4 more
europepmc   +1 more source

Elevated serum CA72-4 predicts gout flares during urate lowering therapy initiation: a prospective cohort study. [PDF]

Rheumatology (Oxford), 2023
Hu S, Sun M, Li M, Xue X, Terkeltaub R, Wang C, Wang M, Lu J, Ran Z, Li H, Ji A, Sun W, Li X, He Y, Liu Z, Zhang H, Wang X, Ji X, Dalbeth N, Li C.   +19 more
europepmc   +1 more source