Results 71 to 80 of about 2,566,374 (138)

Treatment of Gout in Patients with CrCl ≤30 mL/min and/or on Hemodialysis: A Review

Rheumato
Gout is highly prevalent in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD), owing to impaired uric acid excretion. However, treating gout in this population is challenging due to concerns about medication safety and ...
Fares Saliba, Omar Mourad, Jonathan Mina, Fadi Haddadin, Laurence Aoun, Shaza Almardini, Saif Abu-baker, Koushik Sangaraju, Gaetano Di Pietro, Daniel Gaballa, Suzanne El-sayegh   +10 more
doaj   +1 more source

Reconsidering Urate-Lowering Therapy in Chronic Kidney Disease- Guideline Driven Perspectives on the Management of Asymptomatic Hyperuricaemia

Journal of the Pakistan Medical Association
Hyperuricaemia is highly prevalent in patients with chronic kidney disease (CKD), primarily due to reduced renal urate excretion. Elevated serum uric acid (SUA) levels have been linked with CKD progression, cardiovascular disease, and mortality. However,
Sourabh Sharma, Sabine Karam, Intissar Haddiya, Sanjay Kalra   +3 more
doaj   +1 more source

Impact of pegloticase on patient outcomes in refractory gout: current perspectives

Open Access Rheumatology: Research and Reviews, 2018
Rita N Cunha,1 Renata Aguiar,1 Filipa Farinha2 1Rheumatology Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal; 2Centre for Rheumatology, University College London, London, UK Abstract: Gout is currently the most frequent cause of ...
Cunha RN, Aguiar R, Farinha F
doaj  

Dual‐Energy CT Demonstrates Multiple Urate Crystal Deposits in the Sternoclavicular Joint, Cricoid Cartilage, and Cervical Ligaments

Clinical Case Reports
A 58‐year‐old male with a history of gout presented with new‐onset neck pain. Dual‐energy CT revealed extensive urate crystal deposition in his cervical part and sternoclavicular joints, an uncommon manifestation.
Chenyang Zhang, Ziyu Wang, Zhihao Zhang, Ertao Jia   +3 more
doaj   +1 more source

Venous thromboembolism in patients with gout and the impact of hospital admission, disease duration and urate-lowering therapy.

, 2019
BACKGROUND: Systemic inflammatory diseases have been associated with increased risk of venous thromboembolism. We aimed to quantify the risk of venous thromboembolism in patients with gout, the most common inflammatory arthritis, and to assess how ...
Roddy, E, Muller, S, Mallen, C, Clarson, L   +3 more
core   +1 more source

Effects of Discontinuation of Urate-Lowering Therapy: A Systematic Review

, 2017
International audienceBACKGROUND: Urate-lowering therapy (ULT) is associated with low rates of adherence, leading to a potential risk of relapse of gouty arthritis, tophi, or urolithiasis.
Perrine Moreau, Giraudeau, Bruno, Virginie Beslon, Annabel Maruani, Hubert Maisonneuve, Maisonneuve, Hubert, Jean-Pascal Fournier, Bruno Giraudeau, Maruani, Annabel, Beslon, Virginie, Fournier, Jean-Pascal, Moreau, Perrine   +11 more
core   +1 more source

Influence of xanthine oxidase inhibitors on all-cause mortality in adults: a systematic review and meta-analysis

Cardiology Journal
Xanthine oxidase inhibitors, including allopurinol and febuxostat, are the first-line treatment of hyperuricemia. This meta-analysis investigated the association between urate-lowering therapy and all-cause mortality in different chronic diseases to ...
Marcin M. Nowak, Mariusz Niemczyk, Sławomir Gołębiewski, Leszek Pączek   +3 more
doaj   +1 more source

Interventions to improve the uptake of urate-lowering therapy for patients with gout: A systematic review

, 2020
Background Gout treatment is suboptimal despite available therapy, with low levels of initiation and persistence of urate-lowering therapy (ULT) in many patients.
Goodyear-Smith F, Ofanoa M, Dalbeth N, Gill I   +3 more
core   +1 more source

Lipid Lowering Therapy According to Clinical Outcomes in Elderly Population

, 2022
A systematic review of statin therapy and other lipid lowering agents and their efficacies in regard to the elderly population. In this review, I have introduced lipid metabolism and storage in the body.
Issa, Rabeh
core  

Multivariate-adjusted predictors of concordance between reported urate-lowering therapy management and the 2012 ACR gout guidelines.

, 2015
ACR: American College of Rheumatology; OR: odds ratio; CI: confidence interval; BSR: Brazilian Society of Rheumatology; CrCl: creatinine clearance. OR lower than 1 represents a reduced chance of concordance with the 2012 ACR gout guidelines.Multivariate ...
Geraldo da Rocha Castelar-Pinheiro (783431), H. Ralph Schumacher Jr. (443559), Ana Beatriz Vargas-Santos (783430), Evandro Silva Freire Coutinho (107557), Naomi Schlesinger (783432), Jasvinder A. Singh (484385)   +5 more
core   +1 more source