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GLUT9b- and ABCG2-mediated collecting duct urate transport uncovers a vasopressin-independent mechanism of renal water reabsorption. [PDF]

open access: yesJ Clin Invest
Hadla M   +11 more
europepmc   +1 more source

SLC52A1 is a neofunctionalized primate urate transporter enabling intestinal urate secretion. [PDF]

open access: yesJ Biol Chem
Yamamoto S   +23 more
europepmc   +1 more source

Glucose Transporters: Structure, Trafficking, Physiology, and Disease Relevance. [PDF]

open access: yesCurr Issues Mol Biol
Cueto-Ureña C   +2 more
europepmc   +1 more source
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Paeonia × suffruticosa Andrews leaf extract and its main component apigenin 7-O-glucoside ameliorate hyperuricemia by inhibiting xanthine oxidase activity and regulating renal urate transporters.

Phytomedicine, 2023
BACKGROUND Hyperuricemia is an important pathological basis of gout and a distinct hazard factor for metabolic syndromes and cardiovascular and chronic renal disease, but lacks safe and effective treatments currently.
Yan Zhang   +9 more
semanticscholar   +1 more source

Data mining-guided alleviation of hyperuricemia by Paeonia veitchii Lynch through inhibition of xanthine oxidase and regulation of renal urate transporters.

Phytomedicine, 2023
BACKGROUND Hyperuricemia (HUA) is a metabolic disease characterized by a high level of uric acid (UA). The extensive historical application of traditional Chinese medicine (TCM) offers a range of herbs and prescriptions used for the treatment of HUA ...
Jiana Du   +6 more
semanticscholar   +1 more source

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