Results 231 to 240 of about 25,978 (275)

Protein Structures of Urea Transporters

Sub-Cellular Biochemistry
Urea transporters (UTs) facilitate the rapid transport of urea from the extracellular space to the intracellular space through a selective transport mechanism driven by urea concentration gradients. Advances in Cryo-electron microscopy and X-ray crystallography have enabled us to solve the homotrimer structures of UT-A and UT-B, which share a common ...
Shenming Huang, Baoxue Yang, Yang Baoxue   +2 more
exaly   +3 more sources

Facilitative Urea Transporters

Journal of Membrane Biology, 2001
C P Smith, Germain Rousselet, Craig P Smith   +2 more
exaly   +4 more sources

Urea Transporters

Sub-Cellular Biochemistry
Jean-Pierre Cartron, Pierre Ripoche
exaly   +4 more sources

Ubiquitination regulates the plasma membrane expression of renal UT-A urea transporters

American Journal of Physiology - Cell Physiology, 2008
The renal UT-A urea transporters UT-A1, UT-A2, and UT-A3 are known to play an important role in the urinary concentrating mechanism. The control of the cellular localization of UT-A transporters is therefore vital to overall renal function.
Craig P Smith
exaly   +2 more sources

Expression of salt and urea transporters in rat kidney during cisplatin-induced polyuria

Kidney International, 2001
Expression of salt and urea transporters in rat kidney during cisplatin-induced polyuria.BackgroundCisplatin (CP) induced polyuria in rats is associated with a reduction in medullary hypertonicity, normally generated by the thick ascending limb (TAL ...
Carolyn A Ecelbarger, Jeff M Sands, William Cacini   +2 more
exaly   +2 more sources

Urea Transport in the Kidney

Comprehensive Physiology, 2011
Abstract Urea transport proteins were initially proposed to exist in the kidney in the late 1980s when studies of urea permeability revealed values in excess of those predicted by simple lipid‐phase diffusion and paracellular transport. Less than a decade later, the first urea transporter was cloned.
Janet D, Klein, Mitsi A, Blount, Jeff M, Sands   +2 more
openaire   +2 more sources

Mammalian urea transporters

Current Opinion in Nephrology and Hypertension, 1996
Urea transporters are membrane proteins that mediate rapid, passive movement of urea across cell membranes. Physiological studies have revealed their significant roles in urea accumulation in the kidney inner medulla, and consequently in the urinary concentrating mechanism.
C, Shayakul, M A, Hediger
openaire   +2 more sources

Renal urea transporters

Current Opinion in Nephrology and Hypertension, 2004
Urea is transported across the kidney inner medullary collecting duct by urea-transporter proteins. Two urea-transporter genes have been cloned from humans and rodents: the UT-A (Slc14A2) gene encodes five protein and eight cDNA isoforms; the UT-B (Slc14A1) gene encodes a single isoform.
openaire   +2 more sources

Transport Characteristics of Urea Transporters

Rapid urea permeation mediated by urea transporters (UTs) is crucial for maintaining normal physiological processes in organisms. UTs not only facilitate urea transport but also water transport, further underscoring their role in maintaining fluid balance.
Zhizhen, Huang, Baoxue, Yang
openaire   +2 more sources

Urea transport in the dogfish kidney

Journal of Experimental Zoology, 1977
AbstractThere is increasing evidence that urea movement across many epithelia involves more than passive diffusion. Of particular interest is the observation that urea transport across the erythrocyte membrane and across the vasopressin‐stimulated urinary bladder of the toad occurs by facilitated diffusion, and can be selectively inhibited by phloretin
R M, Hays, S D, Levine, J D, Myers, H O, Heinemann, M A, Kaplan, N, Franki, H, Berliner   +6 more
openaire   +2 more sources