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Research progress on pathophysiology, diagnosis and treatment of uric acid stones [PDF]
Uric acid stones are a common type of stone in the urinary system being the only stone that can be dissolved by drugs. The incidence of uric acid stone is increasing worldwide. It is very important to have an in depth understanding of the pathogenesis of
ZHANG Kaineng, KE Changxing
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Variation of Serum Uric Acid Is Associated With Gut Microbiota in Patients With Diabetes Mellitus
Diabetes mellitus is a metabolic disease closely related to a disordered gut microbiome. Diabetic patients usually suffer from various metabolic disorders, such as increased serum uric acid levels.
Weifeng Zhang +13 more
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Effect and Research Progress of Uric Acid Lowering Components in Food
Every year more and more people is suffering from hyperuricemia in China, but the drugs used in clinical to lower uric acid have certain side effects and the treatment costs are relatively high.
Yueting LUAN +5 more
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Progress on the role of ABCG2 and SLC2A9 in the onset of hyperuricemia and gout [PDF]
ABCG2 and SLC2A9 encode the uric acid transporters ABCG2 and GLUT9. ABCG2 single nucleotide polymorphism (SNP) can reduce the expression and transport function of ABCG2 protein, and then cause intestinal uric acid excretion dysfunction, resulting in the ...
YANG Lijuan, DONG Qiumei, WU Hao
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Background: Studies have shown that serum uric acid levels and uric acid-related ratios, such as uric acid-to-albumin ratio (UAR), uric acid-to-creatinine ratio (UCR), uric acid-to-high-density lipoprotein cholesterol (HDL cholesterol) ratio (UHR), and ...
Okan Dikker +4 more
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Serum uric acid in smokers [PDF]
Objectives: To demonstrate the possible effect of smoking on serum uric acid level. Methods: The study was conducted during the period from March to June 2008 in Mosul city as a case control study.
Bassam E Hanna +2 more
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Uric acid (UA) is the end product of purine metabolism in humans due to the loss of uricase activity by various mutations of its gene during the Miocene epoch, which led to humans having higher UA levels than other mammals. Furthermore, 90% of UA filtered by the kidneys is reabsorbed, instead of being excreted.
Bonifacio, Álvarez-Lario +1 more
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Engineering Escherichia coli for diagnosis and management of hyperuricemia
Uric acid disequilibrium is implicated in chronic hyperuricemia-related diseases. Long-term monitoring and lowering of serum uric acid levels may be crucial for diagnosis and effective management of these conditions.
Gozde Gencer +6 more
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Men have higher circulating levels of uric acid than women. This sex difference is suspected to be a result of suppressive effects of estradiol on uric acid. If so, estradiol would be inversely associated with circulating uric acid.
Yutang Wang, Fadi J. Charchar
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