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Research progress on pathophysiology, diagnosis and treatment of uric acid stones [PDF]
Yixue xinzhi zazhi, 2022 Uric acid stones are a common type of stone in the urinary system being the only stone that can be dissolved by drugs. The incidence of uric acid stone is increasing worldwide. It is very important to have an in depth understanding of the pathogenesis of
ZHANG Kaineng, KE Changxing
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Progress on the role of ABCG2 and SLC2A9 in the onset of hyperuricemia and gout [PDF]
Jichu yixue yu linchuang, 2023 ABCG2 and SLC2A9 encode the uric acid transporters ABCG2 and GLUT9. ABCG2 single nucleotide polymorphism (SNP) can reduce the expression and transport function of ABCG2 protein, and then cause intestinal uric acid excretion dysfunction, resulting in the ...
YANG Lijuan, DONG Qiumei, WU Hao
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Variation of Serum Uric Acid Is Associated With Gut Microbiota in Patients With Diabetes Mellitus
Frontiers in Cellular and Infection Microbiology, 2022 Diabetes mellitus is a metabolic disease closely related to a disordered gut microbiome. Diabetic patients usually suffer from various metabolic disorders, such as increased serum uric acid levels.
Weifeng Zhang +13 more
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Effect and Research Progress of Uric Acid Lowering Components in Food
Shipin gongye ke-ji, 2023 Every year more and more people is suffering from hyperuricemia in China, but the drugs used in clinical to lower uric acid have certain side effects and the treatment costs are relatively high.
Yueting LUAN +5 more
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Children, 2023 Background: Studies have shown that serum uric acid levels and uric acid-related ratios, such as uric acid-to-albumin ratio (UAR), uric acid-to-creatinine ratio (UCR), uric acid-to-high-density lipoprotein cholesterol (HDL cholesterol) ratio (UHR), and ...
Okan Dikker +4 more
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Engineering Escherichia coli for diagnosis and management of hyperuricemia
Frontiers in Bioengineering and Biotechnology, 2023 Uric acid disequilibrium is implicated in chronic hyperuricemia-related diseases. Long-term monitoring and lowering of serum uric acid levels may be crucial for diagnosis and effective management of these conditions.
Gozde Gencer +6 more
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Redox Report, 2022 Introduction Uric acid and edaravone might exert a neuroprotective effect in amyotrophic lateral sclerosis (ALS) by reducing oxidative stress. We analyzed whether the treatment effect of edaravone is pronounced in patients whose uric acid level increased
Hee Jo Han +4 more
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Scientific Reports, 2021 Men have higher circulating levels of uric acid than women. This sex difference is suspected to be a result of suppressive effects of estradiol on uric acid. If so, estradiol would be inversely associated with circulating uric acid.
Yutang Wang, Fadi J. Charchar
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Biomedicines, 2023 Several studies have showed that hyperuricemia is related to the development of ischemic heart disease (IHD). There is also growing evidence indicating that hyperuricemia may contribute to the progression of IHD as a pathogenic factor.
Sung-Bum Lee +4 more
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The Role of the Intestine in the Development of Hyperuricemia
Frontiers in Immunology, 2022 Gout is a common inflammatory arthritis caused by the deposition of sodium urate crystals in the joints. Hyperuricemia is the fundamental factor of gout.
Hui Yin +5 more
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