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Research progress on pathophysiology, diagnosis and treatment of uric acid stones [PDF]

open access: yesYixue xinzhi zazhi, 2022
Uric acid stones are a common type of stone in the urinary system being the only stone that can be dissolved by drugs. The incidence of uric acid stone is increasing worldwide. It is very important to have an in depth understanding of the pathogenesis of
ZHANG Kaineng, KE Changxing
doaj   +1 more source

Variation of Serum Uric Acid Is Associated With Gut Microbiota in Patients With Diabetes Mellitus

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Diabetes mellitus is a metabolic disease closely related to a disordered gut microbiome. Diabetic patients usually suffer from various metabolic disorders, such as increased serum uric acid levels.
Weifeng Zhang   +13 more
doaj   +1 more source

TOXICITY OF URIC ACID. [PDF]

open access: yesThe Lancet, 1905
n ...
Luff, ArthurP, Hare, Francis
openaire   +5 more sources

Effect and Research Progress of Uric Acid Lowering Components in Food

open access: yesShipin gongye ke-ji, 2023
Every year more and more people is suffering from hyperuricemia in China, but the drugs used in clinical to lower uric acid have certain side effects and the treatment costs are relatively high.
Yueting LUAN   +5 more
doaj   +1 more source

Progress on the role of ABCG2 and SLC2A9 in the onset of hyperuricemia and gout [PDF]

open access: yesJichu yixue yu linchuang, 2023
ABCG2 and SLC2A9 encode the uric acid transporters ABCG2 and GLUT9. ABCG2 single nucleotide polymorphism (SNP) can reduce the expression and transport function of ABCG2 protein, and then cause intestinal uric acid excretion dysfunction, resulting in the ...
YANG Lijuan, DONG Qiumei, WU Hao
doaj   +1 more source

The Association of Serum Uric Acid Levels and Various Uric Acid-Related Ratios with Insulin Resistance and Obesity: A Preliminary Study in Adolescents

open access: yesChildren, 2023
Background: Studies have shown that serum uric acid levels and uric acid-related ratios, such as uric acid-to-albumin ratio (UAR), uric acid-to-creatinine ratio (UCR), uric acid-to-high-density lipoprotein cholesterol (HDL cholesterol) ratio (UHR), and ...
Okan Dikker   +4 more
doaj   +1 more source

Serum uric acid in smokers [PDF]

open access: yesالمجلة العراقية للصيدلة, 2010
Objectives: To demonstrate the possible effect of smoking on serum uric acid level. Methods: The study was conducted during the period from March to June 2008 in Mosul city as a case control study.
Bassam E Hanna   +2 more
doaj   +1 more source

Uric acid and evolution [PDF]

open access: yesRheumatology, 2010
Uric acid (UA) is the end product of purine metabolism in humans due to the loss of uricase activity by various mutations of its gene during the Miocene epoch, which led to humans having higher UA levels than other mammals. Furthermore, 90% of UA filtered by the kidneys is reabsorbed, instead of being excreted.
Bonifacio, Álvarez-Lario   +1 more
openaire   +2 more sources

Engineering Escherichia coli for diagnosis and management of hyperuricemia

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Uric acid disequilibrium is implicated in chronic hyperuricemia-related diseases. Long-term monitoring and lowering of serum uric acid levels may be crucial for diagnosis and effective management of these conditions.
Gozde Gencer   +6 more
doaj   +1 more source

Establishment of sex difference in circulating uric acid is associated with higher testosterone and lower sex hormone-binding globulin in adolescent boys

open access: yesScientific Reports, 2021
Men have higher circulating levels of uric acid than women. This sex difference is suspected to be a result of suppressive effects of estradiol on uric acid. If so, estradiol would be inversely associated with circulating uric acid.
Yutang Wang, Fadi J. Charchar
doaj   +1 more source

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