Results 1 to 10 of about 5,044,123 (364)

Establishment of sex difference in circulating uric acid is associated with higher testosterone and lower sex hormone-binding globulin in adolescent boys

open access: yesScientific Reports, 2021
Men have higher circulating levels of uric acid than women. This sex difference is suspected to be a result of suppressive effects of estradiol on uric acid. If so, estradiol would be inversely associated with circulating uric acid.
Yutang Wang, Fadi J. Charchar
doaj   +2 more sources

Uric acid and hypertension [PDF]

open access: yesHypertension Research, 2020
Masanari Kuwabara   +2 more
openaire   +3 more sources

Research progress on pathophysiology, diagnosis and treatment of uric acid stones [PDF]

open access: yesYixue xinzhi zazhi, 2022
Uric acid stones are a common type of stone in the urinary system being the only stone that can be dissolved by drugs. The incidence of uric acid stone is increasing worldwide. It is very important to have an in depth understanding of the pathogenesis of
ZHANG Kaineng, KE Changxing
doaj   +1 more source

Progress on the role of ABCG2 and SLC2A9 in the onset of hyperuricemia and gout [PDF]

open access: yesJichu yixue yu linchuang, 2023
ABCG2 and SLC2A9 encode the uric acid transporters ABCG2 and GLUT9. ABCG2 single nucleotide polymorphism (SNP) can reduce the expression and transport function of ABCG2 protein, and then cause intestinal uric acid excretion dysfunction, resulting in the ...
YANG Lijuan, DONG Qiumei, WU Hao
doaj   +1 more source

Effect and Research Progress of Uric Acid Lowering Components in Food

open access: yesShipin gongye ke-ji, 2023
Every year more and more people is suffering from hyperuricemia in China, but the drugs used in clinical to lower uric acid have certain side effects and the treatment costs are relatively high.
Yueting LUAN   +5 more
doaj   +1 more source

Variation of Serum Uric Acid Is Associated With Gut Microbiota in Patients With Diabetes Mellitus

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Diabetes mellitus is a metabolic disease closely related to a disordered gut microbiome. Diabetic patients usually suffer from various metabolic disorders, such as increased serum uric acid levels.
Weifeng Zhang   +13 more
doaj   +1 more source

Uric Acid and Hypertension: a Review of Evidence and Future Perspectives for the Management of Cardiovascular Risk

open access: yesHYPERTENSION, 2022
Uric acid is the final product of purine metabolism, and its increased serum levels have been directly involved in the pathogenesis and natural history of hypertension.
C. Borghi   +4 more
semanticscholar   +1 more source

The Association of Serum Uric Acid Levels and Various Uric Acid-Related Ratios with Insulin Resistance and Obesity: A Preliminary Study in Adolescents

open access: yesChildren, 2023
Background: Studies have shown that serum uric acid levels and uric acid-related ratios, such as uric acid-to-albumin ratio (UAR), uric acid-to-creatinine ratio (UCR), uric acid-to-high-density lipoprotein cholesterol (HDL cholesterol) ratio (UHR), and ...
Okan Dikker   +4 more
doaj   +1 more source

SGLT2 Inhibition and Uric Acid Excretion in Patients with Type 2 Diabetes and Normal Kidney Function

open access: yesAmerican Society of Nephrology. Clinical Journal, 2022
Visual Abstract Background and objectives Sodium-glucose transporter 2 (SGLT2) inhibitor–induced uric acid lowering may contribute to kidney-protective effects of the drug class in people with type 2 diabetes. This study investigates mechanisms of plasma
Danii L. S. Suijk   +12 more
semanticscholar   +1 more source

Uric Acid in Inflammation and the Pathogenesis of Atherosclerosis

open access: yesInternational Journal of Molecular Sciences, 2021
Hyperuricemia is a common metabolic syndrome. Elevated uric acid levels are risk factors for gout, hypertension, and chronic kidney diseases. Furthermore, various epidemiological studies have also demonstrated an association between cardiovascular risks ...
Y. Kimura, D. Tsukui, H. Kono
semanticscholar   +1 more source

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