Results 11 to 20 of about 5,112,493 (265)
Scientific Reports, 2021 Men have higher circulating levels of uric acid than women. This sex difference is suspected to be a result of suppressive effects of estradiol on uric acid. If so, estradiol would be inversely associated with circulating uric acid.
Yutang Wang, Fadi J. Charchar
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Research progress on pathophysiology, diagnosis and treatment of uric acid stones [PDF]
Yixue xinzhi zazhi, 2022 Uric acid stones are a common type of stone in the urinary system being the only stone that can be dissolved by drugs. The incidence of uric acid stone is increasing worldwide. It is very important to have an in depth understanding of the pathogenesis of
ZHANG Kaineng, KE Changxing
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Progress on the role of ABCG2 and SLC2A9 in the onset of hyperuricemia and gout [PDF]
Jichu yixue yu linchuang, 2023 ABCG2 and SLC2A9 encode the uric acid transporters ABCG2 and GLUT9. ABCG2 single nucleotide polymorphism (SNP) can reduce the expression and transport function of ABCG2 protein, and then cause intestinal uric acid excretion dysfunction, resulting in the ...
YANG Lijuan, DONG Qiumei, WU Hao
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Uric Acid and Oxidative Stress—Relationship with Cardiovascular, Metabolic, and Renal Impairment
International Journal of Molecular Sciences, 2022 Background: The connection between uric acid (UA) and renal impairment is well known due to the urate capacity to precipitate within the tubules or extra-renal system.
Mihai-Emil Gherghina +5 more
semanticscholar +1 more source
Effect and Research Progress of Uric Acid Lowering Components in Food
Shipin gongye ke-ji, 2023 Every year more and more people is suffering from hyperuricemia in China, but the drugs used in clinical to lower uric acid have certain side effects and the treatment costs are relatively high.
Yueting LUAN +5 more
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Variation of Serum Uric Acid Is Associated With Gut Microbiota in Patients With Diabetes Mellitus
Frontiers in Cellular and Infection Microbiology, 2022 Diabetes mellitus is a metabolic disease closely related to a disordered gut microbiome. Diabetic patients usually suffer from various metabolic disorders, such as increased serum uric acid levels.
Weifeng Zhang +13 more
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HYPERTENSION, 2022 Uric acid is the final product of purine metabolism, and its increased serum levels have been directly involved in the pathogenesis and natural history of hypertension.
C. Borghi +4 more
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Anti-inflammatory effect of SGLT-2 inhibitors via uric acid and insulin
Cellular and Molecular Life Sciences, 2022 Sodium–glucose cotransporter 2 (SGLT-2) inhibitors (i) reduce cardiovascular and renal events in patients with and without type 2 diabetes (T2D). However, the underlying mechanisms are debated.
Rosalba La Grotta +12 more
semanticscholar +1 more source
The Influence of Serum Uric Acid on the Brain and Cognitive Dysfunction
Frontiers in Psychiatry, 2022 Uric acid is commonly known for its bad reputation. However, it has been shown that uric acid may be actively involved in neurotoxicity and/or neuroprotection.
Nataša R Mijailović +2 more
semanticscholar +1 more source
Deep morphological recognition of kidney stones using intra-operative endoscopic digital videos [PDF]
Physics in Medicine & Biology 2022, 2022 The collection and the analysis of kidney stone morphological criteria are essential for an aetiological diagnosis of stone disease. However, in-situ LASER-based fragmentation of urinary stones, which is now the most established chirurgical intervention, may destroy the morphology of the targeted stone.
arxiv +1 more source