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Current Opinion in Nephrology and Hypertension, 2003
The goal of this article is to review the physiology and describe newly defined molecular mechanisms that are responsible for renal urate transport.Four complementary DNAs have recently been cloned whose expressed proteins transport urate. Two of these proteins have been localized to the apical membrane of proximal tubular cells: one, a urate ...
Mohammed A Rafey +3 more
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The goal of this article is to review the physiology and describe newly defined molecular mechanisms that are responsible for renal urate transport.Four complementary DNAs have recently been cloned whose expressed proteins transport urate. Two of these proteins have been localized to the apical membrane of proximal tubular cells: one, a urate ...
Mohammed A Rafey +3 more
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Pediatric Nephrology, 2013
Uric acid, the end product of purine metabolism, is excreted predominantly by the proximal tubules. Abnormal serum levels of uric acid are due to alterations in production or excretion. Fractional excretion of uric acid is helpful in determining the underlying etiology of hypouricemia or hyperuricemia in children.
Monica T. Cramer, Sahar Fathallah-Shaykh
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Uric acid, the end product of purine metabolism, is excreted predominantly by the proximal tubules. Abnormal serum levels of uric acid are due to alterations in production or excretion. Fractional excretion of uric acid is helpful in determining the underlying etiology of hypouricemia or hyperuricemia in children.
Monica T. Cramer, Sahar Fathallah-Shaykh
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Detection of uric acid based on doped ZnO/Ag2O/Co3O4 nanoparticle loaded glassy carbon electrode
New Journal of Chemistry, 2019Highly sensitive and selective uric acid sensor was fabricated using facile wet-chemically prepared ternary doped ZnO/Ag2O/Co3O4 nanoparticles onto glassy carbon electrode by electrochemical approach, which introduced a prospective and reliable route to ...
M. M. Alam +5 more
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Uric Acid Metabolism and Uric Acid Stones
2010Uric acid nephrolithiasis comprises 8–10% of patients with kidney stone disease. However, this prevalence is higher in particular ethnic populations and in certain regions of the world. The major pathophysiologic mechanism for uric acid nephrolithiasis is unduly acidic urine.
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Current Hypertension Reports, 2006
Epidemiologic studies published during the past 3 years support the possible role of uric acid in the onset of essential hypertension. Data from several large, longitudinal cardiovascular disease studies indicate that elevated serum uric acid is a predictor of incident hypertension and blood pressure progression.
Takahiko Nakagawa +4 more
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Epidemiologic studies published during the past 3 years support the possible role of uric acid in the onset of essential hypertension. Data from several large, longitudinal cardiovascular disease studies indicate that elevated serum uric acid is a predictor of incident hypertension and blood pressure progression.
Takahiko Nakagawa +4 more
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Update in uric acid, hypertension, and cardiovascular diseases
Hypertension Research, 2023M. Kuwabara +7 more
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Seminars in Nephrology, 2005
Increased uric acid level is a key clinical feature of preeclampsia; higher levels correlate with significant maternal and fetal morbidity and mortality. The cause of hyperuricemia and its specific role in the pathogenesis of preeclampsia, however, remain unclear.
Duk Hee Kang +3 more
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Increased uric acid level is a key clinical feature of preeclampsia; higher levels correlate with significant maternal and fetal morbidity and mortality. The cause of hyperuricemia and its specific role in the pathogenesis of preeclampsia, however, remain unclear.
Duk Hee Kang +3 more
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Uric acid and hypertension: a focused review and practical recommendations.
Journal of Hypertension, 2019: Uric acid levels are higher in humans than in other mammals. Best known as an extracellular antioxidant, uric acid also increases salt sensitivity, fat storage, and lipogenesis.
Benjamin de Becker +3 more
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Uric Acid as a Cause of the Metabolic Syndrome.
Contributions to Nephrology, 2018Hyperuricemia is common in subjects with obesity, metabolic syndrome, and type 2 diabetes. For many years, hyperuricemia was attributed to the effects of insulin resistance to reduce urinary excretion of uric acid, and it was believed that uric acid may ...
Christopher King +5 more
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Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2015
Nephrolithiasis is a common condition in the general population. About 5-10% of all kidney stones is composed of uric acid, however the prevalence of uric acid stones significantly increases among patients with obesity, diabetes or metabolic syndrome.
Ferraro, Pietro Manuel +1 more
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Nephrolithiasis is a common condition in the general population. About 5-10% of all kidney stones is composed of uric acid, however the prevalence of uric acid stones significantly increases among patients with obesity, diabetes or metabolic syndrome.
Ferraro, Pietro Manuel +1 more
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