Results 41 to 50 of about 133,008 (211)

Characterization of the complete uric acid degradation pathway in the fungal pathogen Cryptococcus neoformans. [PDF]

PLoS ONE, 2013
Degradation of purines to uric acid is generally conserved among organisms, however, the end product of uric acid degradation varies from species to species depending on the presence of active catabolic enzymes. In humans, most higher primates and birds,
I Russel Lee, Liting Yang, Gaseene Sebetso, Rebecca Allen, Thi H N Doan, Ross Blundell, Edmund Y L Lui, Carl A Morrow, James A Fraser   +8 more
doaj   +1 more source

ON THE SYNTHESIS OF URIC ACID. [PDF]

The Lancet, 1886
n ...
openaire   +2 more sources

The Development of Reproducible and Selective Uric Acid Biosensor by Using Electrodeposited Polytyramine as Matrix Polymer

Indonesian Journal of Chemistry, 2017
A versatile method for the construction of reproducible and high selective uric acid biosensor is explained. Electrodeposited polytyramine is used as biosensor matrixes due to its compatibility to immobilize enzyme uric oxidase in the membrane electrode.
Manihar Situmorang, Isnaini Nurwahyuni
doaj   +1 more source

Uric acid disrupts hypochlorous acid production and the bactericidal activity of HL-60 cells

Redox Biology, 2018
Uric acid is the end product of purine metabolism in humans and is an alternative physiological substrate for myeloperoxidase. Oxidation of uric acid by this enzyme generates uric acid free radical and urate hydroperoxide, a strong oxidant and ...
Larissa A.C. Carvalho, João P.P.B. Lopes, Gilberto H. Kaihami, Railmara P. Silva, Alexandre Bruni-Cardoso, Regina L. Baldini, Flavia C. Meotti   +6 more
doaj   +1 more source

URIC ACID – HISTORY, PRESENT AND FUTURE [PDF]

Romanian Medical Journal, 2019
2,6,8-trioxypurine known as uric acid represents a heterocyclic derivative of purine, with a molecular weight of 158 Da. In contrast to primates and humans, in the other animals uric acid is further oxidized by the uricase enzyme (urate oxidase) to ...
Alexandra Totan, Maria Greabu, Iulia I. Stanescu, Cosmin Totan, Ana Maria Alexandra Stanescu, Marina Melescanu-Imre   +5 more
doaj   +1 more source

Effects of Marine Fish Oligopeptide Composite Preparation on Reducing Uric Acid and Repairing Kidney Damage

Shipin gongye ke-ji
Objective: To investigate the effects of marine fish oligopeptide composite preparation (MFOCP) on reducing uric acid and repairing kidney damage and the underlying mechanisms.
Zijia LU, Yu GAO, Yao XIE, Fengqin FENG
doaj   +1 more source

The Relationship of Acute Exacerbation Severity with Uric Acid and Uric Acid to Creatinine Ratio in Patients with Chronic Obstructive Pulmonary Disease

Haseki Tıp Bülteni, 2013
Aim: Acute exacerbation in chronic obstructive pulmonary disease (COPD) may result in a lot of systemic consequences due to hypoxemia and systemic inflammation.
Sinem Özbay Özyılmaz, İsa Özyılmaz, Osman Akın Serdar, Esra Uzaslan   +3 more
doaj   +1 more source

Effects of allopurinol and febuxostat on uric acid transport and transporter expression in human umbilical vein endothelial cells.

PLoS ONE
Uric acid induces radical oxygen species formation, endothelial inflammation, and endothelial dysfunction which contributes to the progression of atherosclerosis.
Karel H van der Pol, Jan Koenderink, Jeroen J M W van den Heuvel, Petra van den Broek, Janny Peters, Imke D W van Bunningen, Jeanne Pertijs, Frans G M Russel, Jim Koldenhof, Wim J Morshuis, Joris van Drongelen, Tom J J Schirris, Andries van der Meer, Gerard A Rongen   +13 more
doaj   +1 more source

THE EFFECT OF PHENYLBUTAZONE ON URIC ACID METABOLISM IN TWO NORMAL SUBJECTS [PDF]

, 1955
James Β. Wyngaarden
openalex   +1 more source

Uric acid and hypertension [PDF]

Hypertension Research, 2020
Masanari Kuwabara, Miguel A. Lanaspa, Ana Andres-Hernando   +2 more
openaire   +2 more sources