Results 41 to 50 of about 242,034 (343)

Uric Acid Deteriorates Load-Free Cell Shortening of Cultured Adult Rat Ventricular Cardiomyocytes via Stimulation of Arginine Turnover

Biology, 2022
Hyperuricemia is a risk factor for heart disease. Cardiomyocytes produce uric acid via xanthine oxidase. The enzymatic reaction leads to oxidative stress in uric-acid-producing cells.
Martin Weber, Rolf Schreckenberg, Klaus-Dieter Schlüter   +2 more
doaj   +1 more source

Serum Uric Acid Levels in Older Adults: Associations With Clinical Outcomes and Implications for Reference Intervals in Those Aged 70 Years and Over

Arthritis Care &Research, EarlyView.
Objective Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged ≥70 years old.
Amanda J. Rickard, Cammie Tran, Hans G. Schneider, Flavia M. Cicuttini, Anita E. Wluka, Ego Seeman, Johannes T. Neumann, Md Nazmul Karim, Zhen Zhou, Sultana Monira Hussain, David P. Q. Clark, Daniel Clayton‐Chubb, Andrew M. Tonkin, Lawrence J. Beilin, Robyn L. Woods, John J. McNeil   +15 more
wiley   +1 more source

Tubular Handling of Uric Acid and Factors Influencing Its Renal Excretion: A Short Review [PDF]

European Medical Journal Nephrology, 2016
In this review, the authors briefly examine the most recent evidence concerning the role of several proteins involved in tubular urate transport. They also analyse the influence of extracellular volume, electrolyte disorders, acid-base imbalance, and ...
Tubular Handling of Uric Acid and Factors Influencing Its Renal Excretion: A Short Review, Gabriele Pricoco, Damiano Cantone, Elisa Marino, Francesca Bruno   +4 more
doaj  

High uric acid model in Caenorhabditis elegans

Food Science and Human Wellness, 2019
To establish experimental high uric acid model in C. elegans. Hypoxanthine, adenine, xanthine, and uric acid were used to treat C. elegans and then hyperuricemic C. elegans was evaluated by allopurinol. Hyperuricemic C. elegans were obtained after normal
Zhenjing Li, Yibin Xue, Nifei Wang, Jingli Cheng, Xiaoying Dong, Qingbin Guo, Changlu Wang   +6 more
doaj   +1 more source

Hubungan Indeks Massa Tubuh Dengan Kadar Asam Urat Darah Pada Penduduk Desa Banjaranyar Kecamatan Sokaraja Kabupaten Banyumas [PDF]

, 2009
Uric acid is a weak acid that distributed throughout the extracellular fluid as a sodium urate . The amount of uric acid on the blood is influenced by dietary intake of purines, uric acid biosynthesis of the body and rate of uric acid excretion ...
Kumalasari, T. S. (Tyas), Purnawan, I. (Iwan), Saryono, S. (Saryono)   +2 more
core  

Gouty arthritis of the spine in a renal transplant patient : a clinical case report: an unusual presentation of a common disease [PDF]

, 2015
Axial gout is a well-documented but uncommon manifestation of gout. Its mimicking nature and the impracticality of axial joint aspiration might considerably delay its diagnosis.
Dhaese, Sofie, STRYCKERS, MARIJKE, Terryn, Wim, VAN DER MEERSCH, HANS, Van Laecke, Steven   +4 more
core   +1 more source

Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout

Arthritis Care &Research, EarlyView.
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source

Simple and Rapid Method for the Determination of Uric Acid-Independent Antioxidant Capacity

Molecules, 2011
Determination of the relative contribution of uric acid level increases to the total measured antioxidative activity could be very useful for testing antioxidative products and their effect on human health.
Darko Modun, Njegomir Radic, Darko Duplancic, Lea Kukoc-Modun   +3 more
doaj   +1 more source

Obese patients with a binge eating disorder have an unfavorable metabolic and inflammatory profile [PDF]

, 2015
To evaluate whether obese patients with a binge eating disorder (BED) have an altered metabolic and inflammatory profile related to their eating behaviors compared with non-BED obese.A total of 115 White obese patients consecutively recruited underwent ...
Aloi, M, Arturi, F, Caroleo, M, De Fazio, P, Rania, M, Ruffo, M, Segura-Garcia, C, Sesti, G, Succurro, E   +8 more
core   +1 more source

Retractions in rheumatology: trends, causes, and implications for research integrity

Arthritis Care &Research, Accepted Article.
Objective We aimed to describe the trends and main reasons for study retraction in rheumatology literature. Methods We reviewed the Retraction Watch database to identify retracted articles in rheumatology. We recorded the main study characteristics, authors’ countries, reasons for retraction, time from publication to retraction, and trends over time ...
Anna Maria Vettori, Michele Iudici
wiley   +1 more source