Results 61 to 70 of about 5,236,042 (380)

Association between serum uric acid levels and mortality: a nationwide community-based cohort study

open access: yesScientific Reports, 2020
Hyperuricemia is associated with all-cause and cardiovascular mortality. However, the threshold value of serum uric acid levels for increased risk of mortality has not been determined.
T. Konta   +13 more
semanticscholar   +1 more source

The research of the relationship between serum uric acid level and all-cause mortality at the beginning of maintenance hemodialysis and one year after diagnosis in hemodialysis patients

open access: yesLinchuang shenzangbing zazhi, 2020
Objective To study the relationship between average serum uric acid level and all-cause mortality in maintenance hemodialysis patients at a single center at the beginning of dialysis and 1 year after dialysis.Methods A retrospective cohort study was ...
DUAN Rui-qiu, ZHAO Wei, ZHAO Hai-dan
doaj  

Theobromine inhibits uric acid crystallization. A potential application in the treatment of uric acid nephrolithiasis.

open access: yesPLoS ONE, 2014
PurposeTo assess the capacity of methylxanthines (caffeine, theophylline, theobromine and paraxanthine) to inhibit uric acid crystallization, and to evaluate their potential application in the treatment of uric acid nephrolithiasis.Materials and ...
Felix Grases   +2 more
doaj   +1 more source

Uric Acid Has Direct Proinflammatory Effects on Human Macrophages by Increasing Proinflammatory Mediators and Bacterial Phagocytosis Probably via URAT1

open access: yesBiomolecules, 2020
The relationship of uric acid with macrophages has not been fully elucidated. We investigated the effect of uric acid on the proinflammatory ability of human macrophages and then examined the possible molecular mechanism involved. Primary human monocytes
Camilo P. Martínez-Reyes   +8 more
semanticscholar   +1 more source

Risk of Hepatotoxicity in Patients With Gout Treated With Febuxostat or Benzbromarone: A Propensity Score–Matched Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective The objective of this study was to evaluate and compare the risk of hepatotoxicity associated with the use of febuxostat and benzbromarone in patients with gout. Methods New users of febuxostat or benzbromarone with monitoring of liver function at least three times in a year after initiation of the study drugs were identified from an ...
Wenyan Sun   +8 more
wiley   +1 more source

Key Trends and Insights in Smart Polymeric Skin Wearable Patches

open access: yesAdvanced Engineering Materials, EarlyView.
Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez   +2 more
wiley   +1 more source

Associations between purine metabolites and clinical symptoms in schizophrenia [PDF]

open access: yes, 2012
Background: The antioxidant defense system, which is known to be dysregulated in schizophrenia, is closely linked to the dynamics of purine pathway. Thus, alterations in the homeostatic balance in the purine pathway may be involved in the pathophysiology
Debra M. Montrose   +9 more
core   +8 more sources

Engineering a Single Amino Acid Bionanozyme for Ultrasensitive Detection of Biomarkers: A WHO‐REASSURE‐ Aligned Approach

open access: yesAdvanced Functional Materials, EarlyView.
A unique 2D bionanozyme, engineered from a single amino acid and copper ions, demonstrates peroxidase‐mimicking catalytic activity. This efficient and simple bionanozyme allows for ultrasensitive, equipment‐free visual detection of key biomarkers in both test and real samples, meeting the WHO‐REASSURE standards for practical diagnostic applications ...
Subrat Vishwakarma   +5 more
wiley   +1 more source

Melinjo seed extract stimulates intestinal ABCG2 expression to reduce serum uric acid levels in hyperuricemic rats

open access: yesJournal of Functional Foods, 2021
Melinjo resveratrol (MjR) is a resveratrol derivative from the seed extract of melinjo (Gnetum gnemon L.). Although it may reduce serum uric acid concentration in humans, the underlying mechanism remains unclear.
Yoshifuru Tamura   +6 more
doaj  

Laser‐Induced Graphene from Waste Almond Shells

open access: yesAdvanced Functional Materials, EarlyView.
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova   +9 more
wiley   +1 more source

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