Gut Microbiota-derived Bile Acids Promote Gamma-secretase Activity Through Interactions with Nicastrin Subunits [PDF]
arXiv, 2023 Alzheimer's disease (AD) has emerged as a progressively pervasive neurodegenerative disorder worldwide. Bile acids, synthesized in the liver and modified by the gut microbiota, play pivotal roles in diverse physiological processes, and their dysregulation in individuals with AD has been well-documented.
arxiv
Simple and Rapid Method for the Determination of Uric Acid-Independent Antioxidant Capacity
Molecules, 2011 Determination of the relative contribution of uric acid level increases to the total measured antioxidative activity could be very useful for testing antioxidative products and their effect on human health.
Darko Modun +3 more
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The effects of carboxylic acids on the aqueous dispersion and electrophoretic deposition of ZrO2 [PDF]
Journal of the European Ceramic Society, Volume 32, Issue 1, 2012,
Pages 235-244, 2013 The agglomeration, electrokinetic properties and electrophoretic deposition behaviour of aqueous suspensions of ZrO2 with carboxylic acid additives were studied in comparison with conventional pH adjustment. It was found that citric acid imparted negative zeta-potential values and electrosteric stabilisation to particles in suspensions at all pH levels.
arxiv +1 more source
PLoS ONE, 2023 BackgroundGout incidence is increasing worldwide; appropriate management of serum uric acid levels and a healthy lifestyle may help its prevention. The popularity of electronic cigarettes and the resultant emergence of dual smokers is increasing. Despite
Yun Seo Jang +4 more
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Nature's Starships. I. Observed Abundances and Relative Frequencies of Amino Acids in Meteorites [PDF]
, 2014 The class of meteorites called carbonaceous chondrites are examples of material from the solar system which have been relatively unchanged from the time of their initial formation. These meteorites have been classified according to the temperatures and physical conditions of their parent planetesimals.
arxiv +1 more source
Progress in research on uric acid metabolism pathway
Linchuang shenzangbing zazhi, 2019 Uric acid is a product of sputum metabolism, and its crease is caused by increase in uric acid production and a decrease in uric acid excretion. The main metabolic pathway of uric acid is present in the kidney, and secondly in the intestine; and the ...
HU Xiao-hua, ZHANG Li-ming
doaj
Effect of Atorvastatin Alone and in Combination with Aspirin on Uric Acid Handling of Normal Rats
Proceedings, 2021 Introduction: Low doses of aspirin and statins are usually given in conjunction to patients with coronary artery disease. Aspirin at low doses is known to cause hyperuricemia in these patients which can further worsen their condition, while statins can ...
Usman Aslam +4 more
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Meteoritic Abundances of Fatty Acids and Potential Reaction Pathways in Planetesimals [PDF]
Icarus, 2019, 319, 685-700, 2018 The origin of fatty acids on the prebiotic Earth is important as they likely formed the encapsulating membranes of the first protocells. Carbon-rich meteorites (i.e., carbonaceous chondrites) such as Murchison and Tagish Lake are well known to contain these molecules, and their delivery to the early planet by intense early meteorite bombardments ...
arxiv +1 more source
Uric acid, an important screening tool to detect inborn errors of metabolism: a case series
BMC Research Notes, 2017 Background Uric acid is the metabolic end product of purine metabolism in humans. Altered serum and urine uric acid level (both above and below the reference ranges) is an indispensable marker in detecting rare inborn errors of metabolism.
Eresha Jasinge +10 more
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Uric Acid is independently associated with diabetic kidney disease: a cross-sectional study in a Chinese population. [PDF]
PLoS ONE, 2015 Association between hyperuricaemia and chronic kidney disease has been studied widely, but the influence of uric acid on the kidneys remains controversial.
Dandan Yan +10 more
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