Results 81 to 90 of about 239,893 (351)

Obese patients with a binge eating disorder have an unfavorable metabolic and inflammatory profile [PDF]

open access: yes, 2015
To evaluate whether obese patients with a binge eating disorder (BED) have an altered metabolic and inflammatory profile related to their eating behaviors compared with non-BED obese.A total of 115 White obese patients consecutively recruited underwent ...
Aloi, M   +8 more
core   +1 more source

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

open access: yesAdvanced Science, EarlyView.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo   +19 more
wiley   +1 more source

Gambaran Kadar Asam Urat Darah Pada Mahasiswa Angkatan 2011 Fakultas Kedokteran Universitas Sam Ratulangi Dengan Indeks Massa Tubuh 18,5-22,9 Kg/m2 [PDF]

open access: yes, 2013
: Increased uric acid levels (hyperuricemia) play a role in the level of morbidity in several diseases. The prevalence of hyperuricemia in Manado and Minahasa is high compared to other regions in Indonesia. Hyperuricemia can occur at a young age.
Kaligis, S. (Stefana)   +2 more
core  

Significance of dietary antioxidants for health [PDF]

open access: yes, 2011
Since evidence became available that free radicals were involved in mechanisms for the development of major diseases, including cardiovascular disease and cancer, there has been considerable research into the properties of natural dietary antioxidants ...
Gordon, Mike
core   +3 more sources

Soluble Uric Acid Is an Intrinsic Negative Regulator of Monocyte Activation in Monosodium Urate Crystal–Induced Tissue Inflammation [PDF]

open access: bronze, 2020
Qiuyue Ma   +8 more
openalex   +1 more source

Nasal Mucosa‐Derived Extracellular Vesicles as a Systemic Antiaging Intervention

open access: yesAdvanced Science, EarlyView.
This study shows that nasal mucosa‐derived extracellular vesicles (nmEVs) exert systemic anti‐ageing effects in mice by restoring circadian rhythm, suppressing cellular senescence, and improving cognitive function. In aged human bone marrow mesenchymal stem cells, nmEVs reverse senescence‐associated phenotypes and reactivate core clock gene expression.
Wentao Shi   +14 more
wiley   +1 more source

Uric acid disrupts hypochlorous acid production and the bactericidal activity of HL-60 cells

open access: yesRedox Biology, 2018
Uric acid is the end product of purine metabolism in humans and is an alternative physiological substrate for myeloperoxidase. Oxidation of uric acid by this enzyme generates uric acid free radical and urate hydroperoxide, a strong oxidant and ...
Larissa A.C. Carvalho   +6 more
doaj   +1 more source

Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment

open access: yesAdvanced Science, EarlyView.
Molybdenum (Mo), with its unique strength, uniform corrosion, and radiopacity, enables innovative biodegradable implants for transformative stroke therapy. Abstract Neurovascular implants for stroke intervention face a critical dilemma: permanent devices (e.g., nitinol stents, platinum coils) often trigger chronic inflammation and recurrence, whereas ...
Yunong Shen   +11 more
wiley   +1 more source

Effect of Training on Physiological and Biochemical Variables of Soccer Players of Different Age Groups [PDF]

open access: yes, 2010
Purpose: To find out the effect of training on selected physiological and biochemical variables of Indian soccer players of different age groups.\ud \ud Methods: A total of 120 soccer players volunteered for the study, were divided (n=30) into 4 groups:
Chandra Dhara, Prakash   +2 more
core   +1 more source

Uric acid and hypertension: Does uric acid lick the joints and bites the heart? [PDF]

open access: yes, 2014
Background: Uric acid a metabolic end product of purine degradation is implicated in gout as aetiology. Its increased levels have also been associated with hypertension, cardiovascular morbidity and mortality.
Vittal BG, Bhaskara K, Naveenkumar GH
core   +1 more source

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