Enzymatic Studies of Glucuronide Formation in Impaired Liver I. Assay Methods For the Determination of Glucuronyl Transferase Activity and Uridine Diphosphate Glucuronic Acid Content of Liver Tissue Using 4-Methyl Umbelliferone as a Glucuronide Receptor; Its Application to Needle Liver Biopsy Tissues [PDF]
, 1962 An attempt was made to apply the method devised by ARIAS for the determination of liver glucuronyl transferase activity using 4-methyl umbelliferone as a glucuronide receptor to the small amounts of liver tissue obtained by needle biopsy.
Taketa, Kazuhisa
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Modulators of Ion Transport in Nasal Polyps: An Measurement of Short-Circuit Current [PDF]
Clinical and Experimental Otorhinolaryngology, 2008 ObjectivesTo examine possible modulators of the ion transport through the apical membrane of the nasal polyps.MethodsThe study was conducted using the freshly-excised nasal polyps from the patients with chronic sinusitis.
Jun Ho Lee +3 more
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OncoTarget, 2016 Although purinergic signaling is important in regulation of immune responses, the therapeutic potential of it in the tumor microenvironment is little defined. In this study, we demonstrate that UDP/P2Y6 signaling facilitates breast cancer metastasis both
Xiaobin Ma +7 more
semanticscholar +1 more source
Synthesis of Uridine Diphosphate-Glucuronic Acid
Chemical and Pharmaceutical Bulletin, 1960 Uridine 5'-phosphoramidate (I) was allowed to react with α-glucuronic acid 1-phosphate (II), and α-uridine diphosphate glucuronic acid (α-UDPGA) (III) was isolated from the reaction mixture by ion exchange chromatography. Likewise, β-UDPGA (V) was produced from (I) and β-glucuronic acid 1-phosphate (IV).
Hiroki Moriyama +4 more
openaire +6 more sources
Enzymatic Studies of Glucuronide Formation in Impaired Liver III. Effects of Carbon Tetrachloride and Ectromelia Virus Infection on Liver Glucuronide Formation in Mouse [PDF]
, 1962 Glucuronide formations by mouse liver homogenate in several liver impairments were studied by using 4-methyl umbelliferone as a glucuronide receptor. The results were as follows : 1.
Taketa, Kazuhisa
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Gilbert’s Syndrome: Terminology, Epidemiology, Genetics, Pathogenesis (Part I)
Zdorovʹe Rebenka, 2016 The aim of the review was the analysis of the literature about the prevalence, etiology, genetics and pathogenesis of Gilbert’s syndrome (GS). The scientific literature regarding GS with the keywords «Gilbert's syndrome», «hyperbilirubinemia», «uridine ...
T.V. Sorokman +2 more
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Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy [PDF]
, 2017 Leishmania pyrimidine salvage is replete with opportunities for therapeutic intervention with enzyme inhibitors or antimetabolites. Their uptake into cells depends upon specific transporters; therefore it is essential to establish whether various ...
Ali, Juma A.M. +7 more
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Isolation of Endogenous Activator of Glucuronide Formation in Liver [PDF]
, 1962 A purified compound of the activator of glucuronide formation was isolated from a boiled extract of rat liver by charcoal adsorption, ethanol fractionation of barium salts, and finally paper and Dowex-l column chromatographies.
Taketa, Kazuhisa
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Annals of Microbiology, 2022 Purpose Uridine diphosphate glucose pyrophosphorylase (UGPase) plays an important role in glucose metabolism, catalyzing the reversible formation and decomposition of UDP-glucose (UDPG).
Chaoran Xia +6 more
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Challenges of drug resistance in the management of pancreatic cancer [PDF]
, 2010 The current treatment of choice for metastatic pancreatic cancer involves single agent gemcitabine or combination of gemcitabine with capecitabine and erlotinib (tyrosine kinase inhibitor).
Akada +119 more
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