Results 61 to 70 of about 22,157 (221)

Profile of Nucleotides and Nucleosides in Taiwanese Human Milk

Pediatrics and Neonatology, 2011
Human milk–borne nucleotides and their related metabolic products have been reported to have important physiological roles in breast-fed infants. The purpose of this study was to measure the concentrations of free nucleotides and nucleosides in human ...
Kuo-Yu Liao, Tzee-Chung Wu, Ching-Feng Huang, Chih-Chung Lin, I-Fei Huang, Lite Wu   +5 more
doaj   +1 more source

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa, Birhanetensay Masresha Altaye, Yuh‐Pyng Sher   +2 more
wiley   +1 more source

HISTOCHEMICAL DEMONSTRATION OF URIDINE DIPHOSPHATE GLUCOSE-GLYCOGEN TRANSFERASE IN ANIMAL TISSUES

, 1961
Polysaccharide was histochemically synthesized in muscle fibers and other tissue cells by using uridine diphosphate glucose as substrate. By revising the method previously described in light of new biochemical and histochemical findings more ...
TADAO TAKEUCHI, GEORGE G. GLENNER
core   +1 more source

Comparative Metabolomics Reveals Key Pathways Associated With the Synergistic Killing of Colistin and Sulbactam Combination Against Multidrug-Resistant Acinetobacter baumannii

Frontiers in Pharmacology, 2019
Background: Polymyxins are a last-line class of antibiotics against multidrug-resistant Acinetobacter baumannii. However, polymyxin resistance can emerge with monotherapy, highlighting the need for synergistic combination therapies.
Mei-Ling Han, Mei-Ling Han, Xiaofen Liu, Tony Velkov, Yu-Wei Lin, Yan Zhu, Darren J. Creek, Christopher K. Barlow, Heidi H. Yu, Zhihui Zhou, Jing Zhang, Jian Li, Jian Li   +12 more
doaj   +1 more source

The function of uridine diphosphate glucose pyrophosphorylase in the lyophilization-stress response of Lactobacillus acidophilus

Annals of Microbiology, 2022
Purpose Uridine diphosphate glucose pyrophosphorylase (UGPase) plays an important role in glucose metabolism, catalyzing the reversible formation and decomposition of UDP-glucose (UDPG).
Chaoran Xia, Xiaoqun Zeng, Liuyang Peng, Daodong Pan, Zhen Wu, Yuxing Guo, Zhendong Cai   +6 more
doaj   +1 more source

Review of Congenital Myasthenic Syndrome Caused by Pathogenic Variants in GFPT1

Muscle &Nerve, EarlyView.
ABSTRACT Glutamine:fructose‐6‐phosphate transaminase 1 (GFPT1) catalyzes the first and rate‐limiting step of the hexosamine biosynthetic pathway (HBP) to generate UDP‐GlcNAc. GFPT1 exon 9 is specifically spliced in in striated muscles, which makes a long isoform of GFPT1 (GFPT1‐L).
Kinji Ohno, Mohammad Nazim, Ruchen Zhang, Paniz Farshadyeganeh, Mikako Ito, Bisei Ohkawara   +5 more
wiley   +1 more source

Bile bilirubin pigment analysis in disorders of bilirubin metabolism in early infancy

, 2001
BACKGROUNDEarly and accurate diagnosis of Crigler-Najjar syndrome, which causes prolonged unconjugated hyperbilirubinaemia in infancy, is important, as orthotopic liver transplantation is the definitive treatment.
M A Preece, McKiernan, P.J., Kelly, D.A., P J McKiernan, Kelly, Deirdre, B Burchell, Clarke, Douglas, Burchell, B, Lee, W. S., Beath, Susan, Baty, D, Clarke, D. J., Preece, M.A., Burchell, B., McKiernan, P. J., Lee, Way Seah, S V Beath, Clarke, DJ, D J Clarke, Clarke, D.J., Preece, Mary, Lee, WS, D Baty, W S Lee, Lee, W S, Beath, S.V., D A Kelly, Baty, D., Preece, M. A., Beath, S. V., McKiernan, Patrick, Kelly, D. A.   +31 more
core   +1 more source

Dietary uridine improves lipid homeostasis in high-fat diet-induced obese mice by regulating liver gene expression and metabolomic profiles

Frontiers in Nutrition
IntroductionObesity is caused by excessive storage of adipose tissue and leads to metabolic disorders. Uridine exerts modulatory effects on lipid metabolism, but the regulatory mechanism in obesity needs further research.MethodsIn this study, the effects
Yilin Liu, Huihui Zhang, Huihui Zhang, Xudong Yang, Chunyan Xie   +4 more
doaj   +1 more source

Comparison of Three Sympatric Desert Lizards: Digestive Tract Structure, Digestive Enzyme Activities, Gut Microbiota, and Metabolites

Integrative Zoology, EarlyView.
We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley   +1 more source

Characterization of uridine-diphosphate dependent flavonoid glucosyltransferase from Oryza sativa

, 2007
We cloned a uridine-diphosphate dependent glycosyl-transferase RUGT-10 from Oryza sativa. The recombinant enzyme was expressed by glutathione-S transferase gene fusion system in Escherichia coli.
Byoung Seok Hong, Na Yeon Kim, Jeong Ho Kim, Bong-gyu Kim, Joong-hoon Ahn, Jeong-Ho Kim, You-Hoon Chong, Na-Yeon Kim, Youhoon Chong, Byoung-Seok Hong   +9 more
core   +1 more source