Results 81 to 90 of about 22,157 (221)

Theoretical pKa prediction of the α-phosphate moiety of uridine 5′-diphosphate-GlcNAc

open access: yes, 2017
The pKa value of the α-phosphate moiety of uridine 5'-diphosphate-GlcNAc (UDP-GlcNAc) has been successfully calculated using density functional theory methods in conjunction with the Polarizable Continuum Models. Theoretical methods were benchmarked over
Bhavani Prasad Vipperla (20126115)   +3 more
core  

Efficient chemoenzymatic synthesis of uridine 5′-diphosphate N-acetylglucosamine and uridine 5′-diphosphate N-trifluoacetyl glucosamine with three recombinant enzymes

open access: yes, 2017
Uridine 5′-diphosphate N-acetylglucosamine (UDP-GlcNAc) is a natural UDP-monosaccharide donor for bacterial glycosyltransferases, while uridine 5′-diphosphate N-trifluoacetyl glucosamine (UDP-GlcNTFA) is its synthetic mimic.
Chen Qi (2803873)   +5 more
core   +1 more source

De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence

open access: yesMicrobiologyOpen, Volume 15, Issue 4, August 2026.
Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi   +2 more
wiley   +1 more source

Uridine Diphosphate-glucose Dehydrogenase as a Prostate Cancer Biomarker Candidate

open access: yes, 2014
Prostate cancer is the most common cancer in men. Early detection and diagnosis could potentially lead to a higher cancer survival rate. In this study, the expression of the enzyme uridine diphosphate-glucose dehydrogenase was examined as a possible ...
Cavanagh, Brittin
core  

The BnTFL1‐BnJAM3‐BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus

open access: yesAdvanced Science, Volume 13, Issue 37, 3 July 2026.
BnaC03.TFL1 and BnaA01.JAM3 form a complex that facilitates the transport of soluble sugars from the seed coat to the embryo by directly activating the expression of BnSWEETs. Furthermore, BnaC03.TFL1 and BnaA01.JAM3 work cooperatively to promote soluble sugar and oil production while suppressing protein deposition.
Jianjun Wang   +8 more
wiley   +1 more source

ANALYSIS OF BILIRUBIN WITH URIDINE-5'-DIPHOSPHATE GLUCURONYLTRANSFERASE.

open access: yes, 1987
Use of bilirubin uridine 5$\sp\prime$-diphosphate glucuronyltransferase, for the analysis of bilirubin was studied. Microsomal suspensions, as well as the solubilized enzyme, demonstrated capacities for a kinetic assay of albumin: bilirubin (1:2 ...
SHIVJI, ALLY.
core  

Bilirubin-uridine diphosphate glucuronosyltransferase (UGT1A1) gene mutations among newborn babies in the Malay population in Kelantan with hyperbilirubinaemia [RJ276. S961 2005 f rb]. [PDF]

open access: yes, 2005
Sindrom Gilbert berpunca daripada keabnormalan pada gen uridine diphosphate-glucuronosyltransferase 1A1 (UGT1A1) yang disebabkan oleh mutasi. Gilbert syndrome is caused by defects in the uridine diphosphateglucuronosyltransferase 1A1 (UGT1A1 ...
Yusoff, Surini, Yusoff, Surini
core  

Metabolism of uridine 5′-diphosphate-glucose in golgi vesicles from pea stems

open access: yes, 1998
Uridine 5′-diphosphate-glucose (UDP-Glc) is transported into the lumen of the Golgi cisternae, where is used for polysaccharide biosynthesis. When Golgi vesicles were incubated with UDP-[3H]Glc, [3H]Glc was rapidly transferred to endogenous acceptors and
Orellana, Ariel, Neckelmann, Guy
core   +1 more source

Structure−Activity Relationships of Uridine 5‘-Diphosphate Analogues at the Human P2Y6 Receptor

open access: yes, 2016
The structure−activity relationships and molecular modeling of the uracil nucleotide activated P2Y6 receptor have been studied. Uridine 5‘-diphosphate (UDP) analogues bearing substitutions of the ribose moiety, the uracil ring, and the diphosphate group ...
Pedro Besada (2487034)   +9 more
core   +2 more sources

A Novel Workflow for Fast Elucidation of Drug Metabolites for Screening—Combining In Silico Metabolite Prediction With Trapped Ion Mobility QTOF‐MS

open access: yesDrug Testing and Analysis, Volume 18, Issue 7, Page 841-851, July 2026.
UHPLC‐timsTOF‐MS with in silico prediction and automated annotation enabled rapid identification of quetiapine metabolites from pHLMs, facilitating their inclusion in targeted LC‐QTOF‐MS urine screening and improving biomarker detection for toxicological applications.
Annette Zschiesche   +5 more
wiley   +1 more source

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