Results 91 to 100 of about 22,157 (221)
Metabolomic effects of CeO2, SiO2 and CuO metal oxide nanomaterials on HepG2 cells
Background To better assess potential hepatotoxicity of nanomaterials, human liver HepG2 cells were exposed for 3 days to five different CeO2 (either 30 or 100 μg/ml), 3 SiO2 based (30 μg/ml) or 1 CuO (3 μg/ml) nanomaterials with dry primary particle ...
Kirk T. Kitchin +4 more
doaj +1 more source
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source
Study of Bil-Uridine Diphosphate Glucuronyl Transferase (BILUDGPT- 1) Mutation in Neonatal Hyperbilirubinaemia with Glucose-6-Phosphate Dehydrogenase Deficiency. [PDF]
Gilbert syndrome is caused by defects in the uridine diphosphate- glucuronosyltransferase 1A1 (UGT1A1) gene. These mutations differ among different populations and many of them have been found to be genetic risk factors for the development of neonatal ...
Mohd Yusoff, Dr Narazah
core
A technique applicable to the cytochemical localization of glycosyltransferases through a series of coupled enzyme reactions is described. Uridine-5'-diphosphate (UDP) formed by glycosyltransferases is first phosphorylated to uridine-5'-triphosphate ...
G R Matyas, D J Morré
core +1 more source
Erythrocyte uridine diphosphate galactose-4-epimerase deficiency identified by newborn screening for galactosemia in the United States [PDF]
Eight infants (two whites and six blacks) with erythrocyte uridine diphosphate galactose-4-epimerase (epimerase) deficiency were identified in four newborn screening programs for galactosemia in the United States.
Ng, Won G. +7 more
core +1 more source
UDP-glucose and MRS2905 agonist-bound states of the purinergic P2Y14 receptor
P2Y14 receptors respond to uracil-diphosphate-hexose conjugates, yet how this receptor selectively recognizes both uracil-nucleotides and hexose moieties of diverse agonists remains unclear.
Jonathan F. Fay +10 more
doaj +1 more source
ENZYMATIC SYNTHESIS OF URIDINE DIPHOSPHATE XYLOSE AND URIDINE DIPHOSPHATE ARABINOSE [PDF]
V, Ginsburg, E F, Neufeld, W Z, Hassid
openaire +2 more sources
ABSTRACT Clarifying the molecular mechanisms underlying salt tolerance in high‐performing sorghum‐sudangrass hybrids can aid the identification of salt tolerance genes. Here, the previously screened salt‐tolerant sorghum‐sudangrass hybrid variety MN9 and the salt‐sensitive variety MN4 were grown in sand‐filled pots.
Yue Shi +4 more
wiley +1 more source
Urinary Recovery of Salicylamide as Its Glucuronide in Liver Disease
An attempt was made to establish the method for the estimation of glucuronide formation in vivo using salicylamide and further to study the alteration in the glucuronide formation in liver disease. The results were as follows: 1.
Taketa, Kazuhisa
core +1 more source
Ribonucleotide reductases (RNRs) are valuable biocatalysts for the biosynthesis of non‐natural deoxyribonucleotide, relevant in fields like medical science and synthetic biology. In this study, we explore the substrate spectrum of two thermostable RNRs and discuss their implications for nucleotide metabolism and biocatalytical applications ...
Lobna Eltoukhy, Christoph Loderer
wiley +1 more source

