Results 141 to 150 of about 4,041 (175)

HPLC analysis of uridine diphosphate sugars: decreased concentrations of uridine diphosphate galactose in erythrocytes and cultured skin fibroblasts from classical galactosemia patients

Clinica Chimica Acta, 1995
Abstract A high performance liquid chromatography (HPLC) method has been developed for the measurement of uridine diphosphate galactose (UDPGal) and uridine diphosphate glucose (UDPGlc) in erythrocytes and cultured skin fibroblasts of normal controls and galactosemia patients.
Yan-Kang Xu, Francine R Kaufman, G N Donnell   +2 more
exaly   +3 more sources

Mutations in Escherichia coli that affect uridine diphosphate glucose pyrophosphorylase activity and galactose fermentation

Biochimica Et Biophysica Acta, 1963
Abstract The metabolism of galactose was studied in two galactose-non-fermenting mutants which were isolated from Escherichia coli strain K12 and classified genetically as Group E by Drs. J. and E. M. Lederberg . One of them, W4597, was found to have a single defect in UDPG pyrophosphorylase (UTP: α- d -glucose-1-phosphate uridylyltranserase, EC 2.
Toshio Fukasawa, K Kurahashi
exaly   +3 more sources

Differences in Uridine Diphosphate Galactose-4-Epimerase between Haemolysates of Newborns and of Adults

Nature, 1967
THIS communication presents an observation not yet reported concerning the effect of exogenous nicotinamide adenine dinucleotide (NAD) on the activity of uridine diphosphate galactose-4-epimerase. This enzyme (formerly called galactowaldenase) was first demonstrated in yeast extract by Leloir1.
Joan E Hodgman, William R Bergren, W G Ng   +2 more
exaly   +3 more sources

Erythrocyte uridine diphosphate galactose-4-epimerase deficiency identified by newborn screening for galactosemia in the United States [PDF]

Screening: Journal of the International Society of Neonatal Screening, 1993
Eight infants (two whites and six blacks) with erythrocyte uridine diphosphate galactose-4-epimerase (epimerase) deficiency were identified in four newborn screening programs for galactosemia in the United States.
Yan-Kang Xu, Tina M Cowan, Miriam G Blitzer   +2 more
exaly   +2 more sources

Interaction between uridine diphosphate galactose and uridine diphosphate galactose 4-epimerase from Escherichia coli

Biochemistry, 1972
Herman M Kalckar
exaly   +3 more sources

Purification and properties of uridine diphosphate galactose-4-epimerase from yeast

Biochemistry, 1968
R A, Darrow, R, Rodstrom
exaly   +3 more sources

Uridine diphosphate galactose 4-epimerase deficiency

European Journal of Pediatrics, 1981
A case of uridine diphosphate galactose (UDP-Gal) 4-epimerase deficiency was discovered by mass screening of newborn infants. UDP-Gal 4-epimerase activity of red blood cells from the patient was found to be remarkably low, i.e., 7.5% of the level in normal controls at comparable ages.
K, Oyanagi, F, Nakata, S, Hirano, H, Sogawa, N, Takayanagi, R, Minami, S, Tsugawa, T, Nakao, N, Ichihara   +8 more
openaire   +2 more sources

Formation of Galactose-1-Phosphate from Uridine Diphosphate Galactose in Erythrocytes from Patients with Galactosemia[31]

Pediatric Research, 1969
R Gitzelmann
exaly   +2 more sources

Reaction of uridine diphosphate galactose 4-epimerase with a suicide inactivator

Biochemistry, 1990
UDPgalactose 4-epimerase from Escherichia coli is rapidly inactivated by the compounds uridine 5'-diphosphate chloroacetol (UDC) and uridine 5'-diphosphate bromoacetol (UDB). Both UDC and UDB inactivate the enzyme in neutral solution concomitant with the appearance of chromophores absorbing maximally at 325 and 328 nm, respectively. The reaction of UDC
G R, Flentke, P A, Frey
openaire   +2 more sources

Myelodysplasia and deficiency of uridine diphosphate–galactose 4-epimerase

The Journal of Pediatrics, 1995
A 4-year-old girl known to have peripheral uridine diphosphate-galactose 4-epimerase deficiency was examined for bruising and thrombocytopenia. She had dysplastic peripheral blood and bone marrow changes, with a global platelet function defect. Uridine diphosphate-galactose-4-epimerase participates in a metabolic pathway that provides substrates for ...
openaire   +2 more sources