Carbohydrate utilization in Streptococcus thermophilus: characterization of the genes for aldose 1-epimerase (mutarotase) and UDPglucose 4-epimerase [PDF]
Journal of Bacteriology, 1990 The complete nucleotide sequences of the genes encoding aldose 1-epimerase (mutarotase) (galM) and UDPglucose 4-epimerase (galE) and flanking regions of Streptococcus thermophilus have been determined. Both genes are located immediately upstream of the S. thermophilus lac operon.
Poolman, Bert +3 more
europepmc +15 more sources
UDPGlucose 4-epimerase from Saccharomyces fragilis. Allosteric kinetics with UDP-glucose as substrate [PDF]
Journal of Biological Chemistry, 1975 UDPglucose 4-epimerase from Saccharomyces fragilis catalyzes a freely reversible reaction between UDP-galactose and UDP-glucose. With UDP-galactose as the substrate the enzyme shows a classical hyperbolic kinetics but when UDP-glucose is used as the substrate a distinct allostericity is observed.
M, Hay, A, Bhaduri
exaly +8 more sources
Distinct functional roles of two active site thiols in UDPglucose 4-epimerase from Kluyveromyces fragilis. [PDF]
Journal of Biological Chemistry, 1992 UDPglucose 4-epimerase from Kluyveromyces fragilis was earlier shown to have two conformationally vicinal thiols at the active site. Upon treatment with diamide, these thiols form a disulfide linkage across the subunits that results in coordinated loss of catalytic activity and coenzyme fluorescence (Ray, M., and Bhaduri, A. (1980) J. Biol. Chem.
H, Bhattacharjee, A, Bhaduri
exaly +8 more sources
An essential histidine residue for the activity of UDPglucose 4-epimerase from Kluyveromyces fragilis. [PDF]
Journal of Biological Chemistry, 1992 UDPglucose 4-epimerase from Kluyveromyces fragilis was completely inactivated by diethylpyrocarbonate following pseudo-first order reaction kinetics. The pH profile of diethylpyrocarbonate inhibition and reversal of inhibition by hydroxylamine suggested specific modification of histidyl residues. Statistical analysis of the residual enzyme activity and
S, Mukherji, A, Bhaduri
exaly +5 more sources
Indian journal of biochemistry & biophysics, 1992 A chromophorics and fluorescent analog of uridine 5'-monophosphate (UMP), a known competitive inhibitor of UDPglucose 4-epimerase was synthesised. This analog, namely 2',3'-O-(2,4,6-trinitrocyclohexadienylidene) uridine 5'-monophosphate, was found to be a powerful reversible inhibitor of UDPglucose 4-epimerase indicating its interaction with the ...
S, Ray, E, Ali, A, Bhaduri
openaire +1 more source
Molecular characterisation of Entamoeba histolytica UDP-glucose 4-epimerase, an enzyme able to provide building blocks for cyst wall formation. [PDF]
PLoS Negl Trop Dis, 2023 Nagode A +5 more
europepmc +1 more source
Galactose epimerase deficiency: lessons from the GalNet registry. [PDF]
Orphanet J Rare Dis, 2022 Derks B +18 more
europepmc +1 more source
Disruption of OsPHD1, Encoding a UDP-Glucose Epimerase, Causes JA Accumulation and Enhanced Bacterial Blight Resistance in Rice. [PDF]
Int J Mol Sci, 2022 Gao Y +13 more
europepmc +1 more source
[13C]-galactose breath test in a patient with galactokinase deficiency and spastic diparesis. [PDF]
JIMD Rep, 2021 Ficicioglu C +6 more
europepmc +1 more source
Integrated metabolomic and transcriptomic analysis reveal the effect of mechanical stress on sugar metabolism in tea leaves (Camellia sinensis) post-harvest. [PDF]
PeerJ, 2023 Hao Z +8 more
europepmc +1 more source