Results 11 to 20 of about 7,626 (203)

Glutamine deprivation triggers NAGK-dependent hexosamine salvage

open access: yeseLife, 2021
Tumors frequently exhibit aberrant glycosylation, which can impact cancer progression and therapeutic responses. The hexosamine biosynthesis pathway (HBP) produces uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), a major substrate for glycosylation ...
Sydney Campbell   +12 more
doaj   +1 more source

Metabolic labeling of the bacterial peptidoglycan by functionalized glucosamine

open access: yesiScience, 2022
Summary: N-Acetylglucosamine (GlcNAc) is an essential monosaccharide required in almost all organisms. Fluorescent labeling of the peptidoglycan (PG) on N-acetylglucosamine has been poorly explored.
Yang Xu   +12 more
doaj   +1 more source

The Interaction Between Intracellular Energy Metabolism and Signaling Pathways During Osteogenesis

open access: yesFrontiers in Molecular Biosciences, 2022
Osteoblasts primarily mediate bone formation, maintain bone structure, and regulate bone mineralization, which plays an important role in bone remodeling.
Jiapeng Ye   +7 more
doaj   +1 more source

The Natural Antimicrobial trans-Cinnamaldehyde Interferes with UDP-N-Acetylglucosamine Biosynthesis and Cell Wall Homeostasis in Listeria monocytogenes

open access: yesFoods, 2021
Trans-cinnamaldehyde (t-CIN), an antimicrobial compound from cinnamon essential oil, is of interest because it inhibits various foodborne pathogens. In the present work, we investigated the antimicrobial mechanisms of t-CIN in Listeria monocytogenes ...
Lei Sun, Gil Rogiers, Chris W. Michiels
doaj   +1 more source

A Mutant Yeast Deficient in Golgi Transport of Uridine Diphosphate N-Acetylglucosamine [PDF]

open access: yesJournal of Biological Chemistry, 1996
Mannan chains of Kluyveromyces lactis mannoproteins are similar to those of Saccharomyces cerevisiae except that they have terminal alpha1-->2-linked N-acetylglucosamine and lack mannose phosphate. In a previous study, Douglas and Ballou (Douglas, R. K., and Ballou, C. E.
Abeijon, Claudia   +3 more
openaire   +3 more sources

Preparation of Uridine Diphosphate- N -Acetylgalactosamine from Uridine Diphosphate- N -Acetylglucosamine by Using Microbial Enzymes [PDF]

open access: yesApplied and Environmental Microbiology, 1981
A method was developed for the large scale preparation of uridine diphosphate- N -acetylgalactosamine (UDP-GalNAc) from uridine diphosphate- N -acetylglucosamine (UDP-GlcNAc) by means of microbial enzymes.
K, Yamamoto, H, Kawai, T, Tochikura
openaire   +2 more sources

Uridine diphosphate N-acetylglucosamine stimulates uptake of nutrients by quiescent BALB/C3T3 cells. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1978
Preincubation of quiescent BALB/C3T3 cells with uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) in conditioned medium resulted in a time- and concentration-dependent stimulation of uptake of 2-deoxyglucose, uridine, and alpha-aminoisobutyric acid over that seen in conditioned medium alone.
Natraj, C V, Datta, P
openaire   +2 more sources

Uridine diphosphate-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinasedeletion in mice leads to lethal intracerebral hemorrhage during embryonic development [PDF]

open access: yesGlycobiology, 2021
AbstractAmong the enzymes of the biosynthesis of sialoglycoconjugates, uridine diphosphate-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE), catalyzing the first essential step of the sialic acid (Sia) de novo biosynthesis, and cytidine monophosphate (CMP)-Sia synthase (CMAS), activating Sia to CMP-Sia, are particularly important.
Henri, Wedekind   +10 more
openaire   +2 more sources

Isolation of Endogenous Activator of Glucuronide For­mation in Liver [PDF]

open access: yes, 1962
A purified compound of the activator of glucuronide formation was isolated from a boiled extract of rat liver by charcoal adsorption, ethanol fractionation of barium salts, and finally paper and Dowex-l column chromatographies.
Taketa, Kazuhisa
core   +1 more source

Molecular cloning of the Golgi apparatus uridine diphosphate-N-acetylglucosamine transporter from Kluyveromyces lactis. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1996
The mannan chains of Kluyveromyces lactis mannoproteins are similar to those of Saccharomyces cerevisiae except that they lack mannose phosphate and have terminal alpha1-->2-linked N-acetylglucosamine. The biosynthesis of these chains probably occurs in the lumen of the Golgi apparatus, by analogy to S. cerevisiae.
Abeijon, Claudia   +2 more
openaire   +3 more sources

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