Glutamine deprivation triggers NAGK-dependent hexosamine salvage
Tumors frequently exhibit aberrant glycosylation, which can impact cancer progression and therapeutic responses. The hexosamine biosynthesis pathway (HBP) produces uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), a major substrate for glycosylation ...
Sydney Campbell +12 more
doaj +1 more source
Metabolic labeling of the bacterial peptidoglycan by functionalized glucosamine
Summary: N-Acetylglucosamine (GlcNAc) is an essential monosaccharide required in almost all organisms. Fluorescent labeling of the peptidoglycan (PG) on N-acetylglucosamine has been poorly explored.
Yang Xu +12 more
doaj +1 more source
The Interaction Between Intracellular Energy Metabolism and Signaling Pathways During Osteogenesis
Osteoblasts primarily mediate bone formation, maintain bone structure, and regulate bone mineralization, which plays an important role in bone remodeling.
Jiapeng Ye +7 more
doaj +1 more source
Trans-cinnamaldehyde (t-CIN), an antimicrobial compound from cinnamon essential oil, is of interest because it inhibits various foodborne pathogens. In the present work, we investigated the antimicrobial mechanisms of t-CIN in Listeria monocytogenes ...
Lei Sun, Gil Rogiers, Chris W. Michiels
doaj +1 more source
A Mutant Yeast Deficient in Golgi Transport of Uridine Diphosphate N-Acetylglucosamine [PDF]
Mannan chains of Kluyveromyces lactis mannoproteins are similar to those of Saccharomyces cerevisiae except that they have terminal alpha1-->2-linked N-acetylglucosamine and lack mannose phosphate. In a previous study, Douglas and Ballou (Douglas, R. K., and Ballou, C. E.
Abeijon, Claudia +3 more
openaire +3 more sources
Preparation of Uridine Diphosphate- N -Acetylgalactosamine from Uridine Diphosphate- N -Acetylglucosamine by Using Microbial Enzymes [PDF]
A method was developed for the large scale preparation of uridine diphosphate- N -acetylgalactosamine (UDP-GalNAc) from uridine diphosphate- N -acetylglucosamine (UDP-GlcNAc) by means of microbial enzymes.
K, Yamamoto, H, Kawai, T, Tochikura
openaire +2 more sources
Uridine diphosphate N-acetylglucosamine stimulates uptake of nutrients by quiescent BALB/C3T3 cells. [PDF]
Preincubation of quiescent BALB/C3T3 cells with uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) in conditioned medium resulted in a time- and concentration-dependent stimulation of uptake of 2-deoxyglucose, uridine, and alpha-aminoisobutyric acid over that seen in conditioned medium alone.
Natraj, C V, Datta, P
openaire +2 more sources
Uridine diphosphate-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinasedeletion in mice leads to lethal intracerebral hemorrhage during embryonic development [PDF]
AbstractAmong the enzymes of the biosynthesis of sialoglycoconjugates, uridine diphosphate-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE), catalyzing the first essential step of the sialic acid (Sia) de novo biosynthesis, and cytidine monophosphate (CMP)-Sia synthase (CMAS), activating Sia to CMP-Sia, are particularly important.
Henri, Wedekind +10 more
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Isolation of Endogenous Activator of Glucuronide Formation in Liver [PDF]
A purified compound of the activator of glucuronide formation was isolated from a boiled extract of rat liver by charcoal adsorption, ethanol fractionation of barium salts, and finally paper and Dowex-l column chromatographies.
Taketa, Kazuhisa
core +1 more source
Molecular cloning of the Golgi apparatus uridine diphosphate-N-acetylglucosamine transporter from Kluyveromyces lactis. [PDF]
The mannan chains of Kluyveromyces lactis mannoproteins are similar to those of Saccharomyces cerevisiae except that they lack mannose phosphate and have terminal alpha1-->2-linked N-acetylglucosamine. The biosynthesis of these chains probably occurs in the lumen of the Golgi apparatus, by analogy to S. cerevisiae.
Abeijon, Claudia +2 more
openaire +3 more sources

