Results 1 to 10 of about 9,353 (186)

YvcK, a protein required for cell wall integrity and optimal carbon source utilization, binds uridine diphosphate-sugars [PDF]

Scientific Reports, 2017
In Bacillus subtilis, Listeria monocytogenes and in two Mycobacteria, it was previously shown that yvcK is a gene required for normal cell shape, for optimal carbon source utilization and for virulence of pathogenic bacteria.
Elodie Foulquier, Anne Galinier
doaj   +6 more sources

UDP-glucose and MRS2905 agonist-bound states of the purinergic P2Y14 receptor [PDF]

Communications Biology
P2Y14 receptors respond to uracil-diphosphate-hexose conjugates, yet how this receptor selectively recognizes both uracil-nucleotides and hexose moieties of diverse agonists remains unclear.
Jonathan F. Fay, Joseph Kousouros, Zhan-Guo Gao, Matteo Pavan, Paola Oliva, Asmita Pramanik, Clayton Meyer, Siva Hariprasad Kurma, Wen Xu, Brian Krumm, Kenneth A. Jacobson   +10 more
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Enzymatic Glycosylation of Ganoderma Terpenoid via Bacterial Glycosyltransferases and Glycoside Hydrolases [PDF]

Biomolecules
Glycosylation is a critical enzymatic modification that involves the attachment of sugar moieties to target compounds, considerably influencing their physicochemical and biological characteristics.
Te-Sheng Chang, Jiumn-Yih Wu, Hsiou-Yu Ding, Tzi-Yuan Wang   +3 more
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GALE variants associated with syndromic manifestations, macrothrombocytopenia, bleeding, and platelet dysfunction

Platelets, 2023
GALE gene encodes the uridine diphosphate [UDP]-galactose-4-epimerase, which catalyzes the bidirectional interconversion of UDP-glucose to UDP-galactose, and UDP-N-acetyl-glucosamine to UDP-N-acetyl-galactosamine.
Ana Marín-Quílez, Christian A. Di Buduo, Rocío Benito, Alessandra Balduini, José Rivera, Jose Maria Bastida   +5 more
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Identification of a carbohydrate recognition motif of purinergic receptors

eLife, 2023
As a major class of biomolecules, carbohydrates play indispensable roles in various biological processes. However, it remains largely unknown how carbohydrates directly modulate important drug targets, such as G-protein coupled receptors (GPCRs).
Lifen Zhao, Fangyu Wei, Xinheng He, Antao Dai, Dehua Yang, Hualiang Jiang, Liuqing Wen, Xi Cheng   +7 more
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Highly efficient production of rebaudioside D enabled by structure-guided engineering of bacterial glycosyltransferase YojK

Frontiers in Bioengineering and Biotechnology, 2022
Owing to zero-calorie, high-intensity sweetness and good taste profile, the plant-derived sweetener rebaudioside D (Reb D) has attracted great interest to replace sugars.
Baodang Guo, Xiaodong Hou, Yan Zhang, Zhiwei Deng, Qian Ping, Kai Fu, Zhenbo Yuan, Yijian Rao   +7 more
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UGT440A1 Is Associated With Motility, Reproduction, and Pathogenicity of the Plant-Parasitic Nematode Bursaphelenchus xylophilus

Frontiers in Plant Science, 2022
Pine wilt disease (PWD) caused by Bursaphelenchus xylophilus is considered a major threat to pine forests worldwide. Uridine diphosphate (UDP)-glycosyltransferases (UGTs) catalyze the conjugation of small lipophilic compounds with sugars and play crucial
Min Wang, Guicai Du, Junna Fang, Linsong Wang, Qunqun Guo, Tingting Zhang, Ronggui Li   +6 more
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Hypothetical protein CuvA (Rv1422) from Mycobacterium tuberculosis H37Rv interacts with uridine diphosphate N-acetylglucosamine as a key precursor of cell wall

Applied Biological Chemistry, 2023
Mycobacterium tuberculosis CuvA (Rv1422, MtCuvA) has previously been suggested that it may play a critical role in nutrient utilization and cell wall synthesis required for physiological adaptation in a host cell, but its biochemical details remain ...
Yoon Chae Jeong, Jihyun Park, Yu Jeong Cheon, Ki Seog Lee   +3 more
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An Untargeted Metabolomics Approach to Study the Variation between Wild and Cultivated Soybeans

Molecules, 2023
The differential metabolite profiles of four wild and ten cultivated soybeans genotypes were explored using an untargeted metabolomics approach. Ground soybean seed samples were extracted with methanol and water, and metabolic features were obtained ...
Fakir Shahidullah Tareq, Raghavendhar R. Kotha, Savithiry Natarajan, Jianghao Sun, Devanand L. Luthria   +4 more
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Arabidopsis thaliana Sucrose Phosphate Synthase A2 Affects Carbon Partitioning and Drought Response

Biology, 2023
Sucrose is essential for plants for several reasons: It is a source of energy, a signaling molecule, and a source of carbon skeletons. Sucrose phosphate synthase (SPS) catalyzes the conversion of uridine diphosphate glucose and fructose-6-phosphate to ...
Laura Bagnato, Edoardo Tosato, Libero Gurrieri, Paolo Trost, Giuseppe Forlani, Francesca Sparla   +5 more
doaj   +1 more source