Results 111 to 120 of about 4,582 (137)

Effect of dl-ethionine on the concentration and synthesis of uridine diphosphate sugars in the liver of rat

International Journal of Biochemistry, 1976
Abstract 1. 1. Ethionine administration to female rats in a dose of 100mg/100g body wt provokes a rise in liver UTP, UDP and UMP quantity at the 4th and 8th hr after treatment. 2. 2. A small decrease in UDP-glucose concentration and no change or an elevation in UDP- N -acetylglucosamine quantity was established at the 4th and 8th hr time ...
R. Tosheva, V. Zhivkov
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Uridine diphosphate-sugar metabolism by sycamore (Acer pseudoplatanus) cambial tissue

Planta, 1972
Extracts of sycamore cambial tissue convert UDP-glucose into UDP-glucuronic acid, and the latter into UDP-xylose and UDP-rhamnose. None of the corresponding galactose series of monosaccharides was formed indicating the absence of epimerases, postulated as an important feature of differentiation.
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The effects of UDP-sugars, UDP and Mg²⁺on uridine diphosphate glucuronosyltransferase activity in human liver microsomes

Xenobiotica, 2017
1. The UDP-glucuronosyltransferase (UGT) enzymes are important in the metabolism, elimination and detoxification of many xenobiotics and endogenous compounds. As extrapolation of in vitro kinetics of drug metabolizing enzymes to predict in vivo clearance rates becomes more sophisticated, it is important to ensure proper optimization of enzyme assays ...
Gurinder, Walia, Alexander D, Smith, Zoe, Riches, Abby C, Collier, Michael W H, Coughtrie   +4 more
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Conformational behavior of nucleotide-sugar in solution: Molecular dynamics and NMR study of solvated uridine diphosphate-glucose in the presence of monovalent cations

Biopolymers, 2001
The nucleotide-sugars are metabolites of primary importance in the biosynthesis of polysaccharides and glycoconjugates since they serve as sugar donors in the reactions of glycosyltransferases, enzymes that displays a high specificity for both donors and acceptors.
Petrova, P., Monteiro, C., Herve Du Penhoat, C., Koca, J., Imberty, A.   +4 more
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Uridine diphosphate sugar-selective conjugation of an aldose reductase inhibitor (AS-3201) by UDP-glucuronosyltransferase 2B subfamily in human liver microsomes

Biochemical Pharmacology, 2004
N-Glucosidation is known as a major metabolic reaction for barbiturates in humans. However, the enzyme(s) involved in this N-glucosidation has not been clarified yet. Thus, to clarify the enzyme(s) involved in the N-glucosidation in human liver microsomes, we investigated the N-glucosyltransferase activity in recombinant UDP-glucuronosyltransferases ...
Kenji, Toide, Yoshiaki, Terauchi, Toshihiko, Fujii, Hiroshi, Yamazaki, Tetsuya, Kamataki   +4 more
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The measurement of the rate of synthesis of uridine diphosphate sugars in animal tissues by [14C]orotate incorporation

International Journal of Biochemistry, 1978
Abstract 1. 1. [ 14 C]orotate incorporation into UDP-sugars was used for in-vivo studies of their synthesis. An equation which takes into account the relative molar specific activity (that of UMP = 100) and concentration of the compound newly formed was proposed to calculate the rate of UDP-sugar formation. 2. 2.
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Borate-aided anion exchange high-performance liquid chromatography of uridine diphosphate-sugars in brain, heart, adipose and liver tissues

Journal of Chromatography A, 2014
In this paper we describe a method optimized for the purification of uridine diphosphate (UDP)-sugars from liver, adipose tissue, brain, and heart, with highly reproducible up to 85% recoveries. Rapid tissue homogenization in cold ethanol, lipid removal by butanol extraction, and purification with a graphitized carbon column resulted in isolation of ...
Sanna, Oikari, Tuula, Venäläinen, Markku, Tammi   +2 more
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Uridine diphosphate N-acetylamino sugar compounds from Staphylococcus aureus strain 209P. I. Amino acid constituents

Archives of Biochemistry and Biophysics, 1959
1. 1. The components of UDP-N-acetylamino sugar compounds accumulated in normal and in penicillin-treated Staphylococcus aureus strain 209P cells were investigated. 2. 2. In these compounds, two additional amino acids, aspartic acid and glycine, were found besides alanine, glutamic acid, and lysine, already known.
Eiji Ito, Nobutoshi Ishimoto, Masahiro Saito   +2 more
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The occurrence of uridine diphosphate N-acetylgalactosamine 6-sulfate in quail egg white and characteristic distribution of sulfated sugar nucleotides in different avian eggs

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1979
A sulfated sugar nucleotide has been isolated from quail egg white, and accounts for nearly 80% of the total sugar nucleotides found in the egg white. Evidence is presented that this nucleotide is uridine diphosphate N-acetylgalactosamine 6-sulfate, an isomer of the 4-sulfated derivative of uridine diphosphate N-acetylgalactosamine previously found in ...
Y, Nakanishi, S, Okuda, M, Tsuji, S, Suzuki   +3 more
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Synthesis of Uridine 5′‐[2‐S‐Pyridyl‐3‐thio‐α‐D‐galactopyranosyl Diphosphate]: Precursor of UDP‐Thiogal Sugar Nucleotide Donor Substrate for β‐1,4‐Galactosyltransferase.

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Jordan, Elhalabi, Kevin G, Rice
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