Results 231 to 240 of about 1,447,470 (338)

Prognostic impact of the acute reactiveness to intravenous administration of tolvaptan sodium phosphate in patients with acute decompensated heart failure. [PDF]

Eur Heart J Open
Ouchi S, Iwata H, Moriya S, Naito R, Takahashi N, Kasai T, Minamino T.   +6 more
europepmc   +1 more source

Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis

Advanced Science, EarlyView.
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao, Ruiyan Ma, Shuai Hao, Xuxin Tan, Xue Zeng, Rui Song, Bing Chen, Zhezhe Cao, Wei Shen, Zhenchun Luo, Jianfeng Huang, He Huang, Liangming Liu, Chenyang Duan   +13 more
wiley   +1 more source

THE SIGNIFICANCE AND TREATMENT OF SOME ABNORMALITIES OF THE URINE IN CHILDREN [PDF]

, 1922
A. Dingwall-Fordyce
openalex   +1 more source

Urine sodium levels post-saline infusion in differentiating non-edematous hyponatremia. [PDF]

Sci Rep
Chienwichai K, Jiwakanon S, Chaiviriyawong K, Wattanakul J, Rojnsaengroung W, Manasuth S, Sangkaew S, Chang A, Mongkolrattanakul P.   +8 more
europepmc   +1 more source

LEDGF Binds H3R17me2a Promoting De Novo Nucleotide Biosynthesis in SETD2 Mutant Clear Cell Renal Cell Carcinoma

Advanced Science, EarlyView.
In SETD2‐mutant ccRCC, the original LEDGF recognition of the H3K36me3 regulatory axis no longer exists. LEDGF interacts with CARM1‐dependent H3R17me2a regulating the transcription of key enzymes in the de novo synthesis pathway. The abnormally elevated LEDGF leads to the accumulation of purine nucleotides in SETD2‐mutant ccRCC, thereby satisfying the ...
Yuwei Zhang, Yuhua Zhou, Yuezhou Zhang, Jing Lv, Yang Shen, Dong Zhang, Bo Liu, Wei Zhao, Junyi Ju, Qingyi Zhu, Ke Wang, Ninghan Feng   +11 more
wiley   +1 more source

ON THE RELATION OF THE SPECIFIC GRAVITY OF URINE TO THE SOLIDS PRESENT. [PDF]

, 1903
John H. Long
openalex   +1 more source

An LC-MS/MS Assay of Irsenontrine, a Novel Phosphodiesterase‑9 Inhibitor, in Human Plasma, Urine and Cerebrospinal Fluid for Application to Clinical Pharmacokinetic Studies. [PDF]

ACS Omega
Hotta K, Doda K, Aluri J, Mano Y.
europepmc   +1 more source

A Mitochondria‐Targeted Nanozyme Platform for Multi‐Pathway Tumor Therapy via Ferroptosis and Cuproptosis Regulation

Advanced Science, EarlyView.
This work reports a mitochondria‐targeted nanozyme platform, MIL‐Cu1.8S‐TPP/FA, which induces potent cuproptosis via localized delivery of Cu1.8S nanodots to mitochondria. Surface‐anchoring these nanodots onto MIL‐88B metal‐organic frameworks enhances both passive and active tumor targeting.
Chenguang Liu, Lingxiao Guo, Yuying Cheng, Jingjie Gao, Hanling Pan, Jiayi Zhu, Danting Li, Liqing Jiao, Caiyun Fu   +8 more
wiley   +1 more source

A Note on the Effect of Purgation on the Creatinine Content of Urine [PDF]

, 1920
David P. Burns
openalex   +1 more source

Urinary oxytocin levels in children meeting a Hospital Dog^®. [PDF]

BMC Complement Med Ther
Risberg A, Larsson A, Bodén U, Edner A.
europepmc   +1 more source