Results 71 to 80 of about 7,182,421 (220)
Responsive Materials, EarlyView.This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang +6 more
wiley +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li +12 more
wiley +1 more source
Rhenium‐Based β‐Galactosidase Probe Allows Senescence Profiling by Mass Cytometry
Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.Senescence‐associated β‐galactosidase (SA‐β‐Gal) activity is a widely accepted biomarker of cellular senescence, yet its integration with other senescence markers has been limited by available detection methods. Here, we introduce ReGal, a mass cytometry‐compatible SA‐β‐Gal activity probe that can be multiplexed with established markers of senescence ...
Adam Tam +4 more
wiley +2 more sources
, 2007 Regulation of skeletal muscle regeneration by macrophages and the urokinase-type plasminogen ...
Scott C. Bryer (7949129)
core +2 more sources
Evolutionary Mechanisms of Coagulation Factors in Cetaceans During Aquatic Adaptation
Integrative Zoology, EarlyView.Compared with Bos taurus, T. truncatus showed shorter prothrombin time and thrombin time but prolonged activated partial thromboplastin time, indicating pathway‐specific remodeling of coagulation. Evolutionary analyses identified 18 positively selected genes and accelerated F11 evolution, while functional assays revealed increased coagulation factor ...
Wenjun Lv +4 more
wiley +1 more source
Related Article from Urokinase-Type Plasminogen Activator Receptor: A Beacon of Malignancy?
, 2008 Related Article from Urokinase-Type Plasminogen Activator Receptor: A Beacon of ...
Ronny Drapkin (130800) +2 more
core +1 more source
The International Journal of Biological Markers, 2000 Hypoxic tumors of patients with squamous cell carcinoma of the head and neck show a consistent trend towards poor treatment outcome. We now report that tumor hypoxia in these patients is correlated with elevated antigen content of the tumor-associated ...
P. Stadler +6 more
doaj +1 more source
International Journal of Dental Hygiene, EarlyView.ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur +6 more
wiley +1 more source
Human monocytes can produce tissue-type plasminogen activator [PDF]
, 1989 Evidence has previously been presented that monocytes and macrophages produce urokinase-type plasminogen activator. We have shown for the first time that human monocytes, when stimulated appropriately in vitro, can produce tissue type-plasminogen ...
Vitti, GF +4 more
core +1 more source
The structure of the urokinase-type plasminogen activator receptor gene [PDF]
Blood, 1994 The cellular receptor for urokinase-type plasminogen activator (uPAR) is a glycosylphosphatidylinositol (GPI)-anchored membrane protein that plays a central role in pericellular plasminogen activation. It contains 313 amino acid residues, including 28 cysteine residues in a pattern of three homologous repeats. The cysteine residue pattern suggests that
J R, Casey +4 more
openaire +3 more sources