Results 121 to 130 of about 8,317,164 (175)

Urokinase -type Plasminogen Activator System in Human Breast Cancer [PDF]

, 2013
Urokinase plasminogen activator (uPA), urokinase plasminogen activator receptor (uPAR) and plasminogen activator inhibitor-1(PAI-1) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a ...
Al-Rawi, Ali Hussien Al-Khafaji, Al-Jubouri, Aftan Faeza, Salim Reyadh   +4 more
core  

Soluble Urokinase-type Plasminogen Activator Receptor (suPAR) as a Biomarker of Neurodysfunction

NeuroMolecular Medicine
Abstract The inflammatory response is essential for host defense, but its persistence can lead to chronic systemic inflammation (CSI). Soluble urokinase-type plasminogen activator receptor (suPAR) has emerged as a reliable biomarker of CSI because elevated levels consistently indicate the presence and progression of chronic disease as
Victoria Linden de Rezende, Khiany Mathias, Lucineia Gainski Danielski, Tatiana Barichello, Fabricia Petronilho   +4 more
openaire   +2 more sources

Regulation of skeletal muscle regeneration by macrophages and the urokinase-type plasminogen activator.

, 2007
Regulation of skeletal muscle regeneration by macrophages and the urokinase-type plasminogen ...
Scott C. Bryer (7949129)
core   +2 more sources

PLAUR+ Neutrophils Drive Anti‐PD‐1 Therapy Resistance in Patients with Hepatocellular Carcinoma by Shaping an Immunosuppressive Microenvironment

Advanced Science
Hepatocellular carcinoma (HCC) is characterized by an immunosuppressive tumor microenvironment (TME) that limits the efficacy of immune checkpoint inhibitors.
Shaoqing Liu, Yanzhao Zhou, Gaoxiang Li, Bingwen Zhu, Fang Wu, Jinxue Zhou, Xiaobing Chen, Bo Qin, Yanxia Gao, Fazhan Wang, Yong Jiang, Wenxin Xu   +11 more
doaj   +1 more source

The influence of radiation treatment options on the urokinase system of plasminogen activation in the blood of patients with metastatic brain lesions

Южно-Российский онкологический журнал
Purpose of the study. To investigate the effects of different radiotherapeutic modalities on parameters of the urokinase-type plasminogen activation system of fibrinolysis in the blood of patients with metastatic brain tumors (MBT).Patients and methods ...
I. A. Goroshinskaya, A. A. Babasinov, I. V. Kaplieva, E. M. Frantsiyants, E. E. Rostorguev, L. K. Trepitaki, Yu. A. Petrova, Yu. A. Fomenko, D. S. Petrov, A. N. Shevchenko, L. Yu. Vladimirova   +10 more
doaj   +1 more source

Soluble urokinase plasminogen activator receptor in vaginally collected amniotic fluid predicting fetal inflammatory response syndrome: a prospective cohort study

BMC Pregnancy and Childbirth
Background Improving noninvasive antenatal diagnosis of fetal inflammatory response syndrome (FIRS) can assist in the evaluation of prenatal risk and reduce perinatal outcomes.
Violeta Gulbiniene, Irena Dumalakiene, Greta Balciuniene, Ingrida Pilypiene, Ieva Narkeviciute, Vitalij Novickij, Gintautas Vysniauskis, Diana Ramasauskaite   +7 more
doaj   +1 more source

Soluble urokinase-type plasminogen activator receptor is a novel biomarker predicting acute exacerbation in COPD

, 2015
Aziz Gumus,1 Nejat Altintas,2 Halit Cinarka,1 Aynur Kirbas,3 Muge Haziroglu,1 Mevlut Karatas,1 Unal Sahin1 1Department of Pulmonary Medicine, School of Medicine, Recep Tayyip Erdogan University, Rize, Turkey; 2Department of Pulmonary Medicine ...
Kirbas A, Sahin U, Karatas M, Gumus A, Altintas N, Cinarka H, Hazıroglu M   +6 more
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Expression of urokinase‐type plasminogen activator, urokinase‐type plasminogen activator receptor, and plasminogen activator inhibitor‐1 and ‐2 in hepatocellular carcinoma

Pathology International, 2000
It has become more and more clear in recent decades that the plasminogen activation system, which includes urokinase‐type plasminogen activator (uPA), urokinase‐type plasminogen activator receptor (uPAR), plasminogen activator inhibitor (PAI)‐1 and PAI‐2, plays a very important role in the aggressiveness of cancer. Using immunohistochemistry and enzyme‐
L, Zhou, Y, Hayashi, T, Itoh, W, Wang, J, Rui, H, Itoh   +5 more
openaire   +2 more sources

A CELLULAR RECEPTOR FOR UROKINASE-TYPE PLASMINOGEN ACTIVATOR

Thrombosis and Haemostasis, 1987
Recent cell biological and biochemical studies on the urokinase-type plasminogen activator (u-PA) have revealed an unsuspected property of this protein: it binds with high affinity and specificity to the plasma membrane of a number of cell types. Hence, while the interaction of tissue-type plasminogen activator (t-PA) with fibrin suggests a preferred ...
Belin, D, Baccino, D, Wohlwend, A, Estreicher, A, Hurate, J, Vassalli, J-D   +5 more
openaire   +2 more sources

Increased Urokinase-Type Plasminogen Activator Receptor and Epidermal Growth Factor Receptor in Serum of Patients With Prostate Cancer

Journal of Urology, 2009
PURPOSE: Prostate cancer cell motility and invasion have been linked to the up-regulated signaling of epidermal growth factor receptor and urokinase-type plasminogen activator receptor.
Marco Dellabella, Rodolfo Montironi, Elisa Pierpaoli   +2 more
exaly   +2 more sources