Results 31 to 40 of about 8,317,164 (175)
BMC Ophthalmology, 2012 Background Corneal ulceration leading to perforation is associated with infectious and non-infectious destructive conditions in the cornea. The fibrinolytic (plasminogen/plasmin) system is considered to contribute to tissue remodeling in the wound ...
Sugioka Koji +5 more
doaj +1 more source
Di-san junyi daxue xuebao, 2022 Objective To explore the predictive value of soluble urokinase-type plasminogen activator receptor (suPAR) for severe acute pancreatitis (SAP). Methods A prospective cohort study was designed to enroll 103 patients with acute pancreatitis who were ...
LI Yang +5 more
doaj +1 more source
The murine urokinase-type plasminogen activator receptor gene
Journal of Biological Chemistry, 1994 The murine urokinase-type plasminogen activator receptor (uPAR) gene has been isolated and its complete nucleotide sequence established. The gene is organized into seven exons comprising 9.5% of the 13,207-base pair region that spans the interval between the transcription initiation and polyadenylation sites.
T T, Suh +3 more
openaire +2 more sources
Urokinase-type plasminogen activator receptor in IgA nephropathy
The Korean Journal of Internal Medicine, 2014 See Article on Page 176-182 IgA nephropathy (IgAN) is the most common pathologic form of primary glomerulonephritis and accounts for up to 50% of cases of this condition diagnosed using renal biopsy in Korea [1]. The most common pathologic findings related to the development of end-stage renal disease were global sclerosis, segmental sclerosis ...
Ahn, Shin-Young, Chin, Ho Jun
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Biomolecules, 2022 Pancreatic cancer is a highly aggressive malignancy that features high recurrence rates and the poorest prognosis of all solid cancers. The urokinase plasminogen activation system (uPAS) is strongly implicated in the pathophysiology and clinical outcomes
Ashna A. Kumar +2 more
doaj +1 more source
Evaluation of alpha 1-antitrypsin and the levels of mRNA expression of matrix metalloproteinase 7, urokinase type plasminogen activator receptor and COX-2 for the diagnosis of colorectal cancer. [PDF]
PLoS ONE, 2013 BACKGROUND: Colorectal cancer (CRC) is the second most common cause of death from cancer in both men and women in the majority of developed countries. Molecular tests of blood could potentially provide this ideal screening tool. AIM: Our objective was to
Luis Bujanda +11 more
doaj +1 more source
PLAUR (plasminogen activator, urokinase receptor) [PDF]
, 2010 Review on PLAUR (plasminogen activator, urokinase receptor), with data on DNA, on the protein encoded, and where the gene is ...
B Jacobsen +5 more
core +1 more source
The receptor for urokinase‐type plasminogen activator is expressed during mouse spermatogenesis [PDF]
FEBS Letters, 1997 Urokinase‐type plasminogen activator (uPA) binds to a plasma membrane receptor (uPAR) that localizes plasmin generation to the cell environment. Mouse spermatozoa have surface‐bound uPA, which appears to be acquired from genital tract secretions at ejaculation.
Zhou, H., Vassalli, Jean-Dominique
openaire +3 more sources
Origin and diversification of the plasminogen activation system among chordates
BMC Evolutionary Biology, 2019 Background The plasminogen (PLG) activation system is composed by a series of serine proteases, inhibitors and several binding proteins, which together control the temporal and spatial generation of the active serine protease plasmin. As this proteolytic
Andrés Chana-Muñoz +8 more
doaj +1 more source
Novel bi- and trifunctional inhibitors of tumor-associated proteolytic systems [PDF]
, 2003 Serine proteases, cysteine proteases, and matrix metalloproteinases (MMPs) are involved in cancer cell invasion and metastasis. Recently, a recombinant bifunctional inhibitor (chCysuPA(19-31)) directed against cysteine proteases and the urokinasetype ...
Sato, Sumito +6 more
core +1 more source