Results 81 to 90 of about 8,317,164 (175)

Soluble Urokinase-Type Plasminogen Activator Receptor Levels in Patients With Schizophrenia [PDF]

Schizophrenia Bulletin, 2014
The etiology of schizophrenia remains largely unknown but alterations in the immune system may be involved. In addition to the psychiatric symptoms, schizophrenia is also associated with up to 20 years reduction in life span. Soluble urokinase-type plasminogen activator receptor (suPAR) is a protein that can be measured in blood samples and reflects ...
Nielsen, Jimmi, Røge, Rasmus, Pristed, Sofie Gry, Viuff, Anne Grethe, Ullum, Henrik, Thørner, Lise Wegner, Werge, Thomas, Vang, Torkel   +7 more
openaire   +3 more sources

How I Investigate Bleeding Disorders of Unknown Cause: Current Diagnostic Pathways and Gaps in Laboratory Investigation

International Journal of Laboratory Hematology, Volume 48, Issue 6, Page 1289-1297, December 2026.
ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic, Faris Karaselimovic, Tim Dreier, Johanna Gebhart   +3 more
wiley   +1 more source

A Narrative Review on Abnormalities in the Hemostatic System in Diabetes Mellitus: Pathophysiology, Clinical Implications, and Therapeutics

Life
Diabetes mellitus (DM) is a complex metabolic disorder associated with a heightened risk of cardiovascular events, largely driven by a hypercoagulable and hypofibrinolytic state.
Sana Rafaqat, Hafsa Hamid, Fakhra Bashir, Hijab Abaid, Aleksandra Klisic, Saira Rafaqat, Filiz Mercantepe   +6 more
doaj   +1 more source

Urokinase-Type Plasminogen Activator Receptor as a Potential PET Biomarker in Glioblastoma [PDF]

Journal of Nuclear Medicine, 2015
Glioblastoma is one of the most malignant types of human cancer, and the prognosis is poor. The development and validation of novel molecular imaging biomarkers has the potential to improve tumor detection, grading, risk stratification, and treatment monitoring of gliomas.
Persson, Morten, Nedergaard, Mette K, Brandt-Larsen, Malene, Skovgaard, Dorthe, Jørgensen, Jesper T, Michaelsen, Signe R, Madsen, Jacob, Lassen, Ulrik, Poulsen, Hans S, Kjaer, Andreas   +9 more
openaire   +3 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, Volume 20, Issue 11, Page 2955-2973, November 2026.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, Volume 20, Issue 11, Page 2569-2583, November 2026.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Soluble urokinase-type plasminogen activator receptor as a prognostic biomarker in critically ill patients.

, 2014
The aim of this study was to assess the role of blood soluble urokinase-type plasminogen activator receptor (suPAR) levels in the diagnosis and prognostication of sepsis in critically ill patients.Journal ArticleSCOPUS: ar.jinfo:eu-repo/semantics ...
Scolletta, Sabino, Taccone, Fabio Silvio, Santonocito, Cristina, Cortés, Diego Orbegozo, Vincent, Jean-Louis, Vincent, Jean Louis, Covajes, Cecilia, Taccone, Fabio, Gottin, Leonardo, Grazulyte, Daiva, Donadello, Katia, Scolletta S, Santonocito C, Cortes DO, Grazulyte D, Covajes C, Vincent JL, Taccone FS, Cortes D. O., Grazulyte D., Covajes C., Taccone F. S., Santonocito C., Donadello K., Vincent J. -L., Gottin L., Scolletta S.   +26 more
core   +1 more source

Soluble urokinase plasminogen activator receptor in one-year prediction of major adverse cardiac events in patients after first myocardial infarction treated with primary percutaneous coronary intervention

Archives of Medical Science, 2018
Introduction Soluble urokinase plasminogen activator receptor (suPAR) level reflects the general condition of the organism and was proved to give independent information in risk stratification of patients.
Rafał N. Wlazeł, Marta Migała, Marzenna Zielińska, Lucjan Pawlicki, Kinga Rośniak-Bąk, Iwona Szadkowska   +5 more
doaj   +1 more source

The Plasma Proteome Mediates the Association Between Workplace Noise Exposure and Psychiatric Disorder Risk

CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
Workplace noise exposure was associated with adverse psychiatric outcomes and plasma proteomic alterations in the UK Biobank. Circulating proteins partially mediated associations with anxiety disorder and major depressive disorder (MDD), while workplace noise‐related protein risk scores provided proteomics‐based measures of individual susceptibility to
Xuan Zhao, Yan Fu, Dan‐Dan Zhang, Wei Xu, Hui‐Fu Wang, Wei Zhang, Jin‐Tai Yu, Lan Tan   +7 more
wiley   +1 more source

Abstract 17717: Association of Depression with Soluble Urokinase- Type Plasminogen Activator Receptor and Other Markers of Inflammation and Immunity

, 2012
Background: Depression, coronary artery disease (CAD), and inflammation may share pathophysiological links. Soluble urokinase-type plasminogen activator receptor (suPAR) is a biomarker of inflammat..
Al Kassem, Hatem, Ghasemzadeh, Nima, Vaccarino, Viola, Manocha, Pankaj, Kumar, Saket, Shah, Amit J., Thorball, Christian W., Sher, Salman, Hammadah, Muhammad, Garcia-Bengochea, Youssef O, Niaz, Adil, Patel, Riyaz S., Syed, Hamid, Veledar, Emir, Tahhan, Ayman Samman, Eapen, Danny J., Kelli, Heval M., Farook, Naureen, Le, Ngoc-Anh, Pimple, Pratik, Nanjundappa, Ravi, Obideen, Malik, Quyyumi, Arshed A., Kabani, Sarah S, Raison, Charles L, Zafari, Rostam, Sperling, Laurence S., Pielak, Tomasz   +27 more
core   +1 more source