Results 121 to 130 of about 99,653 (320)

The Ly49E receptor inhibits the immune control of acute Trypanosoma cruzi infection [PDF]

, 2016
The protozoan parasite Trypanosoma cruzi circulates in the blood upon infection and invades various cells. Parasites intensively multiply during the acute phase of infection and persist lifelong at low levels in tissues and blood during the chronic phase.
Almeida, Andrade, Antunez, Aune, Avilan, Bern, Cardillo, Carlier, Carnaud, Cesari, Collins, Culbertson, Dowling, Duthie, Duthie, Duthie, Filtjens, Fraser, Frosch, Gritz, Hanke, Keating, Lieke, Lieke, Mekkawy, Meyer Zum Buschenfelde, Mondino, Nagata, Nogueira, Pettengill, Pinazo, Rassi, Robertson, Rottenberg, Santana, Sardinha, Stevenaert, Taveirne, Torrico, Truyens, Truyens, Truyens, Une, Van Beneden, Van Beneden, Van Den Broeck, Van Den Broeck, Vassalli, Wen   +48 more
core   +2 more sources

Low‐Intensity Focused Ultrasound‐Responsive Nanobubbles Enhance Thrombus Targeting and Penetration for Highly Effective Thrombolytic Therapy

Small Structures, EarlyView.
Low‐intensity focused ultrasound (LIFU)‐responsive nanobubbles (PAF@M) specifically target thrombus sites and penetrate thrombi under LIFU stimulation. Meanwhile, the liquid–gas phase transition of perfluoropentane and the release of nitric oxide synergistically enhance ultrasonic cavitation to destroy thrombus structure, providing a safe and effective
Wenli Zhang, Maoyuan Sun, Lian Xu, Sijin Chen, Xiyue Rong, Junrui Wang, Jia Liu, Bo Liu, Jie Xu, Ying Luo, Qianying Du, Yi Wang, Yun Liu, Zhigang Wang, Haitao Ran, Dajing Guo   +15 more
wiley   +1 more source

Cardiovascular Disease Biomarkers and suPAR in Predicting Decline in Renal Function: A Prospective Cohort Study

Kidney International Reports, 2017
Soluble urokinase-type plasminogen activator receptor (suPAR) strongly predicts outcomes and incident chronic kidney disease (CKD) in patients with cardiovascular disease (CVD). Whether the association between suPAR and CKD is a reflection of its overall
Salim S. Hayek, Yi-An Ko, Mosaab Awad, Hina Ahmed, Brandon Gray, Kareem Mohammed Hosny, Hiroshi Aida, Melissa J. Tracy, Changli Wei, Sanja Sever, Jochen Reiser, Arshed A. Quyyumi   +11 more
doaj   +1 more source

Development of immunoassays for human urokinase [PDF]

Radioimmune assays (RIA) and enzyme linked immune assays for measurement of pro-urokinase and the two active forms of the enzyme were developed. Polyclonal and monoclonal antibodies, with desired specificities against preselected synthetic regions of ...
Atassi, M. Zouhair
core   +1 more source

Tumor Dormancy Induced by Downregulation of Urokinase Receptor in Human Carcinoma Involves Integrin and MAPK Signaling

Journal of Cell Biology, 1999
Mechanisms that regulate the transition of metastases from clinically undetectable and dormant to progressively growing are the least understood aspects of cancer biology. Here, we show that a large (∼70%) reduction in the urokinase plasminogen activator
J. Ghiso, K. Kovalski, L. Ossowski
semanticscholar   +1 more source

Temporary inferior vena cava filter combined with catheter contact thrombolysis in the treatment of acute pulmonary embolism secondary to pelvic vein thrombosis

Zhongguo linchuang yanjiu
Objective To investigate the treatment methods and efficacy of acute pulmonary embolism. Methods The diagnosis and treatment information of 8 patients with APE secondary to pelvic vein thrombosis admitted by the Changsha First Hospital from 2020 to 2021 ...
LIU Yangzhen, YAN Peng
doaj   +1 more source

Selection Of A Novel Aptamer Against Vitronectin Using Capillary Electrophoresis And Next Generation Sequencing [PDF]

, 2016
Breast cancer (BC) results in ≃40,000 deaths each year in the United States and even among survivors treatment of the disease may have devastating consequences, including increased risk for heart disease and cognitive impairment resulting from the toxic ...
Boyacioglu, O., Colyer, C. L., Debinski, W., Gmeiner, W. H., Herpai, D. M., Marini, F. C., Qasem, S., Riley, Kathryn R., Stuart, C. H.   +8 more
core   +3 more sources

Permeable Lung Vasculature Creates Chemoresistant Endothelial Niche by Producing SERPINE1 at Breast Cancer Metastatic Sites

Cancer Science, EarlyView.
Vascular permeability is increased by lung metastasis, which correlates with YAP activation in ECs. Activated ECs provide SERPINE1 to neighboring cancer cells to promote chemoresistance and stemness. ABSTRACT Chemotherapy resistance remains a major obstacle for eradicating metastatic cancer cells in distant organs. We identified that endothelial cells (
Tsunaki Hongu, Sarenqiqige, Shandan, Hirokazu Kusunoki, Akihiko Ishimura, Takeshi Suzuki, Thordur Oskarsson, Noriko Gotoh   +7 more
wiley   +1 more source

Urokinase-type Plasminogen Activator and Plasminogen Activator Inhibitor Induction by Etoposide in a Glioblastoma Cell Strain

Food Technology and Biotechnology, 2002
Urokinase plasminogen activator (uPA) and its inhibitors (PAI) are elements of plasminogen activation system, a proteolytic system involved in many physiological and patological processes.
Branko Brdar, Maja Matulić
doaj  

Obesity‐related glomerulopathy: How it happens and future perspectives

Diabetic Medicine, EarlyView.
Abstract Obesity‐related glomerulopathy (ORG) is an emerging complication of excess adiposity. Its incidence rises alongside the obesity pandemic. Up to 40% of individuals can be affected by ORG, irrespective of the status of glomerular filtration rate and albuminuria.
Jian‐Wen Samuel Lee‐Boey, Jia‐Kai Tan, Zhan‐Foong Lim, Francesco Zaccardi, Kamlesh Khunti, Majid Ezzati, Edward W. Gregg, Lee‐Ling Lim   +7 more
wiley   +1 more source